For Linux Computer Only ---

Part 1: Set up Gurobi, the optimization solver

1. Register or login Gurobi
2. Download Gurobi Optimizer
   1. You can put the Gurobi optimizer anywhere in your computer. Suppose you put the optimizer directory, e.g., gurobi702, under the path: "(your defined path for gurobi main program)/gurobi702.
   2. Paste the following commands in the "~/.bashrc" and the "~/.bash_profile" file (you need to do so before setting up the license, or the command "grbgetkey" used to fetch the license cannot be recognized)
      • export GUROBI_HOME="(your defined path for gurobi main program)/linux64"
      • export PATH="${PATH}:${GUROBI_HOME}/bin"
      • export LD_LIBRARY_PATH="${LD_LIBRARY_PATH}:${GUROBI_HOME}/lib"
      • export LD_LIBRARY_PATH="${GUROBI_HOME}/lib"
      • export GRB_LICENSE_FILE=(your defined path for gurobi licence)/gurobi.lic
   3. Execute the following command in a terminal window:
      • source ~/.bashrc
3. Fetch Gurobi license
   • Move the license, e.g., "gurobi.lic", to the designated location according to the ".bashrc" file. For example: "(your defined path for gurobi licence)/gurobi.lic"

Part 2: Download Mengchu&Ming Design Automation for Microfluidics (MMDA-M) for Linux

Part 3: Draw in AutoCAD

1. Enter command "osnap". Turn off "Object Snap".
2. Enter command "script". Select the .scr file generated by Columba. The automatically-synthesized design should be available now!!