2025/2 -
Assistant professor, Department of Computer Science, University of Taipei
臺北市立大學 資訊科學系
2021/4 - 2025/1
Assistant professor, Department of Bioinformatics and Medical Engineering, Asia University
亞洲大學 生物資訊與醫學工程學系
Research Scholar, Institute of Information Science, Academia Sinica
中央研究院 資訊所
Postdoctoral Researcher, Institute of Information Science, Academia Sinica
中央研究院 資訊所
Postdoctoral Researcher, Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo, Japan
日本 (東京) 產業技術総合研究所
Editorial Board member
Scientific Reports. 2026/4 - Present
Editorial Board member
BMC Bioinformatics. 2026/4 - Present
Bioinformatics
Artificial intelligence, large language models, and agentic AI
Natural language processing
Computational proteomics
Ph.D., Bioinformatics Program, Taiwan International Graduate Program (TIGP), Academia Sinica, Taiwan / 中央研究院國際研究生學程 - 生物資訊學程
In cooperation with Institute of Bioinformatics and Systems Biology, National Chiao Tung University / 國立交通大學 生物資訊及系統生物研究所
M.S., Computer and Information Science, National Chiao Tung University, Taiwan / 國立交通大學 資訊科學系 碩士
B.S., Computer and Information Science, National Chiao Tung University, Taiwan / 國立交通大學 資訊科學系 學士
指導專題生黃瑞麟榮獲「科技部大專學生研究計劃」經費補助,題目:基於異質模型Ensemble Learning與自動化超參數優化之高精度神經胜肽識別系統開發. 2026/7.
指導實驗室專題生朱苡綾、劉柏妘榮獲「2026智創未來- 生成式AI創意競賽」邏輯思維設計組金牌獎 (共計450+隊參賽),主題:運用智能型資料擴增與蛋白質語言模型的功能性胜肽預測平台. 2026/6.
Gold Medal Award in the Logical Thinking Design Category at the 2026 Generative AI Creative Design Competition (In total 450+ participating teams). Project title: A Functional Peptide Prediction Platform Utilizing Intelligent Data Augmentation and Protein Language Models.
指導專題生王睿孺、李亞欣、陳韜宇、尹懌碩榮獲亞大生醫系「114學年度畢業專題競賽」第一名,題目:MINAS: Mandarin Intelligent Narrative Assessment of Syntax for Children. 2026/3.
First Place Award in the 114th Academic Year Senior Project Competition of BIME, Asia University.
指導專題生陳立凱、陳芷嫻、傅宥翔榮獲亞大生醫系「114學年度畢業專題競賽」第二名,題目:Predicting anti-aging peptides through integrated protein language model embeddings and sequence features. 2026/3.
Second Place Award in the 114th Academic Year Senior Project Competition of BIME, Asia University.
指導專題生曾琪淇榮獲亞大生醫系「114學年度畢業專題競賽」第三名,題目:Sequence-based predictions of anti-inlammatory peptides using machine learning approaches. 2026/3.
Third Place Award in the 114th Academic Year Senior Project Competition of BIME, Asia University.
指導專題生鄭筠蓁、王婷萱榮獲亞大生醫系「114學年度畢業專題競賽」佳作,題目:Computational Method for IL-6-inducing Peptide Prediction. 2026/3.
Merit Award in the 114th Academic Year Senior Project Competition of BIME, Asia University.
指導外籍碩士生Tadeo Pontjoharyo參加「2025生成式人工智慧創新應用國際競賽」獲得佳作. Title: From Language to Biology: Protein Language Model-Generated Synthetic Data Enables Accurate Blood-Brain Barrier Penetrating Peptide Prediction. 2025/12.
Merit Award in the 2025 International Generative Artificial Intelligence Innovation Application Competition.
指導學生王睿孺、李亞欣、陳韜宇、尹懌碩參加「2025 全國 AI 專題創意競賽」榮獲跨領域組第三名 (共112隊參與競賽). 題目:CARA -- Children's Assisted Real-time Narrative Assessment. 2025/12.
Third Place in the Interdisciplinary Category at the 2025 National AI Project Creativity Competition (112 participating teams).
指導學生朱苡綾、鄭筠蓁參加「2025 全國 AI 專題創意競賽」榮獲跨領域組佳作 (共112隊參與競賽). 題目:基於蛋白質語言模型的功能性胜肽預測方法. 2025/12.
Merit Award in the Interdisciplinary Category at the 2025 National AI Project Creativity Competition (112 participating teams). Project title: Functional Peptide Prediction Method Based on Protein Language Model.
榮獲臺北市立大學114年度教師研究成果獎勵. 2025/12.
Faculty Research Award from the University of Taipei.
指導學生鄭筠蓁、尹懌碩、林浚瑋參加中央研究院統計所舉辦「2025資料科學漫步」榮獲優選獎. 題目:以機器學習方法與多元特徵預測幼兒社會與情緒能力. 2025/11.
Excellence Award of the "2025 Data Science Odyssey" hosted by the Institute of Statistical Science, Academia Sinica. Title: Predicting Early Childhood Social and Emotional Competence Using Machine Learning Methods and Diverse Features.
指導學生王睿孺、李亞欣、陳韜宇參加「中技社AI創意競賽」榮獲佳作. (共54 隊伍/教師69人/學生189人參賽) 題目:MINA -- 兒童敘事能力評估與臨床建議系統. 2025/11.
Merit Award for the CTCI Foundation AI Innovation Competition (54 participating teams). Project title:"MINA -- Mandarin Intelligent Narrative Assessment for Children.
指導學生李亞欣、王睿孺、陳韜宇參與「智創未來 : 2025 生成式AI創意設計競賽」榮獲企業創新獎 (200+ 隊伍參賽),題目:(MAIN-AI) 以大語言模型進行兒童敘事能力檢測與分析 (與亞洲大學聽力暨語言治療學系張顯達講座教授合作). 2025/6.
Corporate Innovation Award at the "Smart Innovation Future: 2025 Generative AI Creative Design Competition" hosted by Asia University (200+ participating teams).
指導學生陳立凱、傅宥翔、陳芷嫻、劉維任、朱苡綾參與「智創未來 : 2025 生成式AI創意設計競賽」榮獲企業創新獎、與邏輯思維設計組第三名 (共200+支隊伍參賽),題目:使用蛋白質語言模型輔助開發抗發炎胜肽藥物 -- 序列生成、預測、以及分析. 2025/6.
Corporate Innovation Award and Third Place in the Logic Design Category at the "Smart Innovation Future: 2025 Generative AI Creative Design Competition" hosted by Asia University (200+ participating teams).
指導學生陳立凱、傅宥翔、陳芷嫻、劉維任參與經濟部舉辦「2025 Best AI Awards 智慧創新大賞」入圍決賽 (共1000+支隊伍參賽, <10%隊伍進入決賽),題目:使用蛋白質語言模型輔助開發抗發炎胜肽藥物 -- 序列生成、預測、以及分析. 2025/4.
Finalist in the 2025 Best AI Awards hosted by the Ministry of Economic Affairs. (1000+ participating teams, less than 10% become finalists)
指導學生周羿妘、李亞欣獲得亞大生醫系「113年畢業專題競賽」第一名. 題目:IQUP--使用機器學習識別定量高誤差圖譜以改善標記化蛋白質體實驗. 2025/02.
First Place in the 113th Academic Year Senior Project Competition of BIME, Asia University. Project title: IQUP-- Machine Learning Approach to Identify Quantitative High-Error Spectra for Improving Isobaric Labeling Proteomics.
指導學生林億祥、侯韻淇、鄧羽芹獲得亞大生醫系「113年畢業專題競賽」第二名. 題目:使用生成式AI合成蛋白質片段以提升IL-13誘導胜肽機器學習預測準確性. 2025/02.
Second Place in the 113th Academic Year Senior Project Competition of BIME, Asia University. Project title: Using Generative AI to Produce Peptides for Improving Machine Learning Prediction Accuracy of IL-13 Inducing Peptides.
指導學生林億祥、傅宥翔、陳芷嫻獲得國科會舉辦「2024 GenAI Stars生成式AI 百工百業應用選拔」創意創客組優選獎,題目:使用生成式AI以提升醫療用胜肽機器學習預測準確性. 2024/10. (500+ 隊伍參賽).
Excellence Award in the "Creative Maker Category" of the 2024 GenAI Stars-- Generative AI Applications Competition (500+ participating teams) hosted by the National Science and Technology Council. Project title: Using Generative AI to Improve Machine Learning Prediction Accuracy for Therapeutic Peptides.
指導學生林億祥獲得「智創未來 : 2024 生成式AI創意設計競賽」邏輯思維設計組金牌獎 & 企業創意獎,題目:使用生成式AI合成蛋白質片段以提升醫療用胜肽機器學習預測準確性--以白介素(IL-13) inducing peptide為例. 2024/6. (200+ 隊伍參賽).
Gold Medal Award & Corporate Creativity Award in the "Logic Design Category" of the Smart Innovation Future: 2024 Generative AI Creative Design Competition (200+ participating teams). Project title: Using Generative AI to Produce Peptides for Improving Machine Learning Prediction Accuracy of Therapeutic Peptides--Taking Interleukin (IL-13) Inducing Peptides as an Example.
指導學生周羿妘、陳立凱、劉維任獲得「智創未來 : 2024 生成式AI創意設計競賽」問題解決組金牌獎 & 企業創意獎,題目:例用生成式AI建構生醫關係網路--以蛋白質交互作用為例. 2024/6. (200+ 隊伍參賽).
Gold Medal Award & Corporate Creativity Award in the "Problem Solving Category" of the Smart Innovation Future: 2024 Generative AI Creative Design Competition (200+ participating teams). Project title: Using Generative AI to Construct Biomedical Networks--Taking Protein-Protein Interaction as an Example.
指導學生游荏捷獲得亞大生醫系「112年畢業專題競賽」第二名 2024/03. 題目:Constructing a VHH paratope predictor using optimized machine learning models.
Second Place in the 112th Academic Year Senior Project Competition of Department of Bioinformatics and Medical Engineering, Asia University. Title: Constructing a VHH paratope predictor using optimized machine learning models.
指導學生蔡敦竹、楊景臣獲得亞大生醫系「112年畢業專題競賽」產業委員獎 (僅取一名) 2024/03. 題目:Constructing hybrid quantitation algorithms for isobaric labeling proteomics.
Industry Committee Award in the 112th Academic Year Senior Project Competition of Department of Bioinformatics and Medical Engineering, Asia University. Title: Constructing hybrid quantitation algorithms for isobaric labeling proteomics.
指導學生「陳思涵、郭邵淳」獲得亞大生醫系「111年畢業專題競賽」並列第一名, 題目:Sequence-based prediction of tumor T-cell antigen, 2023/02.
First place in the 112th Academic Year Senior Project Competition of Department of Bioinformatics and Medical Engineering, Asia University. Title: Sequence-based prediction of tumor T-cell antigen.
指導學生「倪寬、游荏捷」獲得亞大生醫系「111年畢業專題競賽」並列第一名,題目:Using machine learning methods to develop a sequence-based prediction model for hemolytic peptides, 2023/02.
First place in the 112th Academic Year Graduation Project Competition of Department of Bioinformatics and Medical Engineering, Asia University.
指導學生榮獲亞洲大學 110學年度APP程式設計競賽,醫學暨健康學院第一名,題目:認識自己一下吧,學生姓名:黃詠郁(心理系)
指導學生榮獲亞洲大學 110學年度APP程式設計競賽,管理學院第二名,題目:酒的小知識,學生姓名:張雅絜(休憩系)
指導學生榮獲亞洲大學 110學年度APP程式設計競賽,管理學院第三名,題目:小酒館,學生姓名:劉育廷(休憩系)
Integrating Protein Language Model Embeddings and Sequence Features for Blood-Brain Barrier Penetrating Peptide Prediction. 混合蛋白質語言模型詞嵌入及序列特徵以預測血腦屏障穿透胜肽. Principal investigator, NSTC 115-2221-E-845-002 (國科會/工程處).
Integration of protein large language models and machine learning for the prediction of anti-aging peptides. 結合蛋白質大型語言模型與機器學習以預測抗老化胜肽. Principal investigator, NSTC 114-2221-E-468-010 (國科會/工程處).
Nanobody paratope prediction based on large language models. 以大型語言模型預測奈米抗體互補位置. Principal investigator, ASIA-113-CMUH-14. (113學年度亞洲大學與中國醫藥大學附設醫院研究平台計畫). (核定/因職務異動未執行).
VHH paratope prediction using artificial intelligence approaches. 使用人工智慧方法預測單域抗體互補位. Principal investigator, NSTC 113-2221-E-468-006 (國科會/工程處).
建構智慧型溝通能力快速評估工具, Co-principal investigator, NSTC 113-2410-H-468-012 (國科會/人文處).
Predicting hemolytic peptides using machine learning methods with two-stage optimization. 以兩階段最佳化機器學習方法預測溶血毒性胜肽. Principal investigator, NSTC 112-2221-E-468-019 (國科會/工程處).
Clinical record deidentification and temporal normalization for AI Cup. 臨床病例去識別化與時間資訊正規化競賽暨標註資料蒐集計畫. Co-principal investigator, Artificial Intelligence Competition and labeled data acqUisition Project (AI Cup)/ Ministry of Education. 2023. (教育部).
Construction of optimized machine learning predictor for VHH paratope prediction. 建構適用於VHH的最佳化paratope機器學習預測方法. Principal investigator, Industry-Academia Cooperative Research Program with AnTaimmu BioMed Corp. 2023. (產學計劃-- 安肽生醫).
Improving isobaric labeling quantitation accuracy with artificial intelligence and data-driven approaches 使用人工智慧以及資料導向方法以提升標記化蛋白質體定量準確性. Principal investigator, MOST 110-2222-E-468-003 (科計部).
Guest Editor for Special Issue titled "Machine Learning for Peptide and Protein Function Prediction" in the International Journal of Molecular Sciences (IJMS, SCI Q1, IF: 5.6).
Program Committee member, The 24th Asia Pacific Bioinformatics Conference (APBC 2026).
Session chair, 2025 International workshop on Deidentification of Electronic Medical Record Notes (IW-DMRN, in collaboration with MedInfo), Taipei International Convention Center, Taipei, 2025.
Session chair, Intelligent Computing Symposium, Taipei, 2025.
Program Committee member, IEEE AIxMHC, Taichung, 2025.
Poster judge, 2023 Annual Symposium of Taiwanese Society of Biomedical Engineering (TSBME), Taoyuan, 2023.
Program Committee member and session chair, The 22nd IEEE International Conference on BioInformatics and BioEngineering (BIBE 2022)
Title: Teaching Machines to Speak Protein: AI for Therapeutic Peptide Discovery. TIGP Social Network and Human-Centric Computing program, Academia Sinica. Nov, 2025. (中央研究院資訊所/國際研究生學程)
Title: Identification of quantitatively unreliable spectra with machine learning for isobaric labeling-based proteomics. The 21th Taiwan Society for Mass Spectrometry Annual Conference (台灣質譜學會第21屆學術研討會). Chang Gung University. July, 2025.
講題:人工智慧科技發展與應用. 台灣石油工會113年度各委員會聯席會議. 台中永豐棧酒店. Sep, 2024.
Title: Improving accuracy of isobaric labeling-based protein quantitation with peptide-spectrum-match filter and spectral library searching. The 19th Taiwan Society for Mass Spectrometry Annual Conference (台灣質譜學會20週年年會暨第19屆學術研討會). 台中金典酒店. July, 2023.
Title: Computational proteomics and its application to cancer tissue data analysis, Taiwan Joint Commission of Precision Medicine (台灣精準醫療品質策進會), Aug. 26, 2022.
Title: Bioinformatics and data science for cancer proteomics research, Department of Computer Science and Information Engineering, Asia University, Apr. 8, 2021.
Title: Automatic proteomics data analysis and isobaric labeling quantitation using WinProphet and Multi-Q 2, Bioinformatics Training Courses of Life Science Library, Academia Sinica, Apr. 7, 2021. (including hands-on training)
Title: Computational proteomics and its application to cancer tissue data analysis, Bioinformatics Program, Taiwan International Graduate Program, Academia Sinica, Feb. 27, 2020.
Title: iTop-Q-- an intelligent top-down proteomics quantitation tool using DYAMOND algorithm for charge state deconvolution, Bioinformatics Program, Taiwan Internation Graduate Program, Academia Sinica. Mar. 22, 2018.
Title: User-friendly tools for proteomics: WinProphet for identification and Multi-Q for isobaric labeling quantitation, Fall Seminar, Taiwan Society of Mass Spectrometry, Academia Sinica. Oct. 20, 2017. (including hands-on training)
Title: Structure-based protein-protein interaction site predictions, Department of Mathematics, Fu-Jen Catholic University, Jun. 1, 2016.
Title: Protein-protein interaction site predictions with three-dimensional probability distributions of interacting atoms on protein surfaces, Computational Bioinformatics Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan, Feb. 28, 2014.
Title: Protein-protein interaction site predictions with three-dimensional probability distributions of interacting atoms on protein surfaces, Graduate Institute of Biomedical Informatics, Taipei Medical University, Nov. 28, 2013.
2026: Genome Biology, BMJ Health and Care Inormatics, npj Drug Discovery.
2025: Computers in Biology and Medicine, Heliyon.
2024: Database, Heliyon, npj Digital Medicine, International Journal of Molecular Sciences.
IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2024).
Molecules (2022)
Asia Pacific Bioinformatics Conference (APBC 2017)
IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2016)
Asia Pacific Bioinformatics Conference (APBC 2015)
IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2015)
PLoS ONE (2014)
Research in Computational Molecular Biology (RECOMB 2014)
Asia Pacific Bioinformatics Conference (APBC 2014)
Research in Computational Molecular Biology (RECOMB 2013)
Asia Pacific Bioinformatics Conference (APBC 2013)
IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2013)
Machine learning / 機器學習: 115-1
Java Programming / Java程式設計: 115-1
Academic writing / 學術論文寫作: 114-2
Deep learning / 深度學習: 114-1, 115-1
Become a Data Explorer: Easy Introduction to Weka Machine Learning / 成為資料探索家 : 輕鬆玩轉Weka機器學習 (第三人生大學/智慧時代:AI與數據啟航計畫學分學程專班): 114-1
Introduction to Python programming / 透過實作app入門Python (通識): 114-1, 115-1
Computer organization / 計算機結構: 113-2, 114-2
Data structure / 資料結構: 113-2
Probability / 機率: 113-2, 114-2
Discrete mathematics / 離散數學: 110-1, 111-1, 112-1, 113-1
Basic programming / 基礎程式設計: 110-1, 111-1, 112-1, 113-1
Programming project / 程式設計專案: 112-2
Introduction to biomedical informatics and medical engineering / 生醫資訊與醫工概論: 110-1, 111-1, 112-1, 113-1
Biological data mining / 生醫資料擷取與探勘: 110-2, 111-2, 112-2
Advanced programming / 進階程式設計: 110-2, 111-2
Program design and artificial intelligence application / 程式設計與智慧應用: 110-2, 111-2
Information and technology / 資訊與科技: 110-1, 111-1
Lecturer, Computational Biology II, Bioinformatics program, Taiwan International Graduate Program, Academia Sinica (2022, 2023, 2024, 2025, 2026). 中央研究院國際研究生-生物資訊學程 (博士班課程). Topic: advanced proteomics algorithms
Lecturer, Computational Biology I, Bioinformatics program, Taiwan International Graduate Program, Academia Sinica (2020, 2021, 2022, 2023, 2024, 2025, 2026). 中央研究院國際研究生-生物資訊學程 (博士班課程). Topic: computational proteomics
Lecturer for Bioinformatics Course of Life Science Library of Academia Sinica (2021, 2022). Topic: Proteomics data analysis using WinProphet and isobaric-labeling quantitation using Multi-Q 2.
Lecturer, Computational Biology II, Bioinformatics program, Taiwan International Graduate Program, Academia Sinica (2021). 中央研究院國際研究生-生物資訊學程. Topic: clustering for cancer subtyping
Lecturer, Computational Biology I, Bioinformatics program, Taiwan International Graduate Program, Academia Sinica (2015, 2016, 2017, 2018, 2019). 中央研究院國際研究生-生物資訊學程. Topic: combinatorial pattern matching, suffix tree and suffix array
2025/11/9 - 12. Kulai, Johor, Kuala Lumpur @ Malaysia.
2025/4/20 - 24. Surabaya & Batam @ Indonesia.
講師, 基礎攝影--理論與實務, 台北市原住民部落大學(2012)
Lecturer, "Photography: Theory and Practice", Taipei Indigenous Community College (2012)
專案攝影講師, 屏東縣春日鄉歸祟村「回歸祟前,請記得我」社區營造專案 (本專案獲得信義房屋 2011年社區一家幸福行動計畫個人獎首獎)
Lecturer, "Basic Photography" (Workshop) — Guey-Chung Community Development Association, Pingtung (2012)
婚禮攝影師 (場次:10+)
Wedding photographer for 10+ wedding events
副社長, 中央研究院攝影社 (2011)
Vice president, Photo Club, Academia Sinica (2011)
資訊長, 中央研究院攝影社 (2010)
Information officer, Photo Club, Academia Sinica (2010)
2013 天下雜誌主辦「觸動.感動 國際攝影大賽」,作品入圍決選 (參賽作品共10,376張)
2013 法鼓山世界青年會「無悔的步履」攝影比賽,作品榮獲優選
2012 台北旅遊網「旅行台北.發現最美」圖文競賽,「都市人物浮世繪」類別榮獲優勝及入選獎,「城市設計狂想曲」類別榮獲佳作及入選獎。
2012 台北市政府觀光傳播局「我心目中的台北」照片入選(入選照片將製作為「台北探索館」十周年館慶特別活動影片)
2012 待磨工作室「徵相.寶藏巖」影像徵選活動榮獲第一名
2011 聯合報「兩岸大交流,你我共參與」競賽「城市印象.隨手拍」類別榮獲佳作獎
2011 原住民文化事業基金會「按.照你」圖文競賽「部落寫真」類別榮獲特優獎,作品於西門町紅樓展出
2011 教育部「閱遊台灣.百聞一見」圖文競賽榮獲第二名,作品出版為筆計書
2011 台北市政府觀光傳播局「台北.一遊未盡」網路圖文競賽,作品入選
2011.5 慢活.輕旅遊 @ 台北市原住民部落大學
2011.10 鏡頭下的原住民 @ 台北市原住民部落大學
Taroko Gorge Marathon (2006), 5 KM
Shihmen Reservoir Swimming Carnival (2004), freestyle swimming for 3 KM
Inline skating instructor, Hsin-Chu (2002)
銀牌, 男子400公尺自由式接力, 國立交通大學 游泳錦標賽 (2001).
Silver Medal, Men's 4 x 100m freestyle relay, NCTU Swimming Tournament (2001)
金牌, 男子400公尺自由式接力, 國立交通大學 游泳錦標賽 (2000).
Gold Medal, Men's 4 x 100m freestyle relay, NCTU Swimming Tournament (2000)
金牌, 男子400公尺混合接力, 國立交通大學 游泳錦標賽 (2000).
Gold Medal, Men's 4 x 100m Medley relay, NCTU Swimming Tournament (2000)
金牌, 男子400公尺自由式接力, 國立交通大學 游泳錦標賽 (1999).
Gold Medal, Men's 4 x 100m freestyle relay, NCTU Swimming Tournament (1999)
金牌, 男子400公尺混合接力, 國立交通大學 游泳錦標賽 (1999).
Gold Medal, Men's 4 x 100m Medley relay, NCTU Swimming Tournament (1999)
金牌, 男子100公尺蛙式, 國立交通大學 新生游泳競賽 (1997)
Gold Medal, Men's 100m Breaststroke, NCTU Freshman Swimming Tournament (1997)
救生員執照, 中華民國紅十字會 (1997)
Lifeguard Certification, The Red Cross Society of Republic of China, (1997)
銅牌, 國立交通大學 新生盃籃球競賽 (1998), 先發控球後衛
Bronze Medal, NCTU Freshman Basketball Tournament, 1998 (served as starting point guard)