MIRDCalc

A Community Tool for Deriving and Reporting Patient Organ Doses in Nuclear Medicine, Computed Tomography, and Hybrid Imaging

MIRDCalc V 1.0

The you for your interest in MIRDcalc internal dosimetry software. The software is not available yet for distribution but will be available shortly.

If you would like to be added to the MIRDcalc email list, and receive updates about the software, please send your name/email to MIRDcalc@gmail.com

Status UPDATE (9/20/2019)

  • We are happy to announce that we have been awarded a US NIH U01 grant, which will ensure the MIRDcalc project is funded through 2024.
  • In summer, 2019, the MIRDcalc project was officially endorsed by the SNMMI MIRD committee.
  • This dose calculation software will be distributed freely in the community to aid with research and dosimetry estimation. We are now working on preparing for distribution of 1st version MIRDcalc. Public release date has yet to be determined. When released, distribution will be free to the community.Please join our mailing list if you would like to receive updates.

About MIRDcalc

MIRDcalc is:

  • A freely distributable platform for organ level dosimetry calculations
  • A platform for innovation in nuclear medicine dosimetry

Internal radiation dosimetry is critical for the development of new diagnostic imaging radiotracers as well as therapeutic applications where dosimetry can be used to personalize treatments. To support our dynamic and expanding field, widely available, user-friendly tools that enable accurate dosimetry calculations are required. In response to this, we have developed MIRDCalc – an organ-level biodistribution-to-dosimetry calculation software tool, built in the universally available Microsoft EXCEL platform.

The MIRDcalc software is being developed in collaboration with the SNMMI MIRD committee.

MIRDcalc organ level dosimetry

    • 333 isotopes (ICRP Publication 107),
    • Family of 12 ICRP phantoms with 79 source organs and 43 target organs each

ICRP voxelized phantoms used in MIRDcalc software

Features of MIRDCalc dosimetry software

    • Intuitive interface
    • Ultrafast (/instant) processing
    • Error propagation/calculation
    • Patient-specific S value adjustment (based on body habitus)
    • Executable via user interface or command line (supports batch processing)
    • Visual quality control checks
    • Standardized input/output

Built in EXCEL platform

    • Robust/intuitive platform
    • Easy to install

Distribution

    • MIRDcalc will be distributed freely in the community
    • Distribution date TBD

Using MIRDcalc

MIRDCalc can be run on any computer with Excel 2013 or later installed. The database powering MIRDCalc stores all necessary information for implementing biodistribution-to-dosimetry calculations using the MIRD schema and incorporates calculation-specific details for 333 isotopes (ICRP Publication 107), a family of 12 ICRP phantoms with 58 source organs and 44 target organs each.

Additional features of mass scaling, error propagation, dynamic remainder-of-body source regions, quality-control checks, and summary graphics are also included. All input and software interactions are provided in a single-screen interface. Don't like MS Excel or user interfaces - MIRDcalc can be called via command line with full features, and thus supports batch processing and automated workflow integration.

The intention is to distribute MIRDCalc freely in the medical and dosimetry community, with open source coding, making this software dependable, and idea for education.

Screenshots