Listed below are the research projects I have conducted in collaboration with others during my PhD. If you would like more information about any of these works, please feel free to contact me at ngum3402@usherbrooke.ca
First Author
M-D. Nguyen, S. Tavakoli, S. Mittelstedt, P. E. Johnson, P. Dauphin-Ducharme, Solution-Based Biophysical Methods for Guiding Design of Aptamers into Electrochemical Biosensors, Analysis & Sensing, 2025, 0, e202500077, DOI.
M.-D. Nguyen, G. T.Prevot, N. Fontaine, P. Dauphin-Ducharme, Whole Blood Theophylline Measurements Using an Electrochemical DNA Aptamer-based Biosensor, ECS Sensors Plus, 2024, 3 030601, DOI.
M.-D. Nguyen, M. T. Osborne, G. T. Prevot; Z. R. Churcher, P. E. Johnson, L. Simine, P. Dauphin-Ducharme, Truncations and in silico Docking to Enhance the Analytical Response of Aptamer-Based Biosensors, Biosensors and Bioelectronics, 2024, 265, 116680, DOI.
*M.-D. Nguyen, K.-N.Nguyen, S. Malo, I. Banerjee, D. Wu, L. Du-Thumm, P. Dauphin-Ducharme, Electrochemical Aptamer-Based Biosensors for Measurements in Undiluted Human Saliva, ACS Sensors, 2023, 8, 12, 4625–4635, DOI.
*Highlighted in https://www.acs.org/pressroom/presspacs/2023/november/swapping-blood-for-spit-for-convenient-at-home-health-monitoring.html
Other Author
Y. A. Kaiyum, E. Hoi Pui Chao, L. Dhar, A. A. Shoara, M.-D. Nguyen, C. D. Mackereth, P. Dauphin-Ducharme, P. E. Johnson, Ligand Induced Folding in a Dopamine-Binding DNA Aptamer, ChemBioChem, 2024, 25, e202400493, DOI.
Preprint
M.-D. Nguyen, K.-A. Yang, L. Coote, C. Vu, A. Shoara, P. E. Johnson, M. N. Stojanovic, P. Dauphin-Ducharme, Exploiting Cross-Reactivity for Selective Chemotherapy Monitoring: A Differential Electrochemical Aptamer Approach, 2026, DOI.
E. Hoi Pui Chao, E. Largy, Y. A. Kaiyum, M.-D. Nguyen, B. Vialet, P. E. Johnson, C. D. Mackereth, Unconventional DNA architecture in a dopamine–bound aptamer complex, Under Review, Nature Communications, 2025, DOI.
Patent
CA3267376A1, EP4587818A1, CN120092177A, Sensor, kit, and method for biomarker detection in saliva, 2023.