Ultrasound-Induced Heating
Ultrasound-induced heating
Ultrasound absorption in a viscoelastic material enables rapid, on-demand control of temperature and its spatial gradient on the microscale.
Biomedical applications
Ultrasound-induce heating offers many advantages over the conventional micoheating methods, such as rapid, volumetric, energy-efficient heating with ability to form a dynamic, free-form temperature gradient. This novel microfluidic heating method enables continuous-flow microfluidic PCR within 3 min and high-resolution DNA melting curve analysis for detection of single nucleotide polymorphisms in DNA.