Reversible Chemistry

Dynamic covalent chemistry (reversible chemistry) is essential in constructing thermodynamically favored molecular architectures in high yields. We have applied this concept in the sysnthesis of:

Macrocycles: We use reversible alkyne metathesis to avoid the creation of long oligomers.

3D-Covalent Organic Frameworks: We use reversible boronic acid/ester formation to create periodic framworks.

Related Publications:

W. Zhang, S. M. Brombosz, J. L. Mendoza, J. S. Moore, J. Org. Chem. 2005, 70, 10198.

H. M. El-Kaderi, J. R. Hunt, J. L. Mendoza-Cortes, A. P. Cote, R. E. Taylor, M. O'Keeffe, O. M. Yaghi Science 2007, 316, 268.

D. J. Tranchemontagne, J. L. Mendoza-Cortes, M. O'Keeffe, O. M. Yaghi, Chem. Soc. Rev. 2009, 38, 1257.