The Meek Lab

Latest News

July 2019: Michael's paper on "Catalytic Enantioselective Synthesis of 1,4-Keto-Alkenylboronate Esters and 1,4-Dicarbonyls" is accepted to Angewandte Chemie. Congrats!

June 2019: Joesph and Shuang's paper on "Enantio- and Diastereoselective Synthesis of Functionalized Carbocycles by Cu-Catalyzed Borylative Cyclization of Alkynes with Ketones" is accepted to Organic Letters. Congrats!

May 2019: Justin, Tia, Rajith, and Courtney's paper on "(CDC)–Rhodium-Catalyzed Hydroallylation of Vinylarenes and 1,3-Dienes with AllylTrifluoroborates" is accepted to ACS Catalysis. Congrats!

August 2018: Stephanie and Michael's recent paper is featured in the 2018 issue of JACS Young Investigators. Congrats!

Synthetic Methods and Organometallic Catalysis at the University of North Carolina at Chapel Hill

Research in my group is involved with the discovery, design, and development of new chiral catalysts and catalytic methods for chemical synthesis. We focus on developing practical and effective catalysts that enable the use of simple and abundant starting materials for useful carbon-carbon and carbon-heteroatom bond forming reactions.

We are interested in understanding reaction mechanisms (efficiency and selectivity) as well as demonstrating and challenging our catalytic transformations (reliability) in efficient enantioselective total synthesis of complex biologically important molecules. Areas of interest include catalysis, stereoselective organic synthesis, and organometallic chemistry.