The Meek Lab
November 2020: Emilie and Joe's paper on "Diastereo-, Enantio-, and anti-Selective Formation of Secondary Alcohol and Quaternary Carbon Stereocenters by Cu-Catalyzed Additions of B-Substituted Allyl Nucleophiles to Carbonyls" is accepted to Organic Letters.
May 2020: Michael's paper on "Synthesis of Quaternary Carbon Stereogenic Centers by Diastereoselective Conjugate Addition of Boron-Stabilized Allylic Nucleophiles to Enones" is accepted to the Journal of the American Chemical Society.
May 2020: Justin and Tiffany's paper on "Enantioselective Synthesis of Functionalized Arenes by Nickel-Catalyzed Siteselective Hydroarylation of 1,3-Dienes with Aryl-Boronates" is accepted to Angewandte Chemie.
Synthetic Methods and Organometallic Catalysis at the University of North Carolina at Chapel Hill
Research in my group is involved with the discovery, design, and development of new chiral catalysts and catalytic methods for chemical synthesis. We focus on developing practical and effective catalysts that enable the use of simple and abundant starting materials for useful carbon-carbon and carbon-heteroatom bond forming reactions.
We are interested in understanding reaction mechanisms (efficiency and selectivity) as well as demonstrating and challenging our catalytic transformations (reliability) in efficient enantioselective total synthesis of complex biologically important molecules. Areas of interest include catalysis, stereoselective organic synthesis, and organometallic chemistry.