The Meek Lab
January 2018: Stephanie and Eugenia's paper on "Synthesis of Alkenyl Boronates from Epoxides with Di-[B(pin)]-methane via Pd-Catalyzed Dehydroboration" is accepted to Org. Lett. Congrats!
October 2017: Justin, Courtney, Raj, and Tia's paper on "Chiral Pincer Carbodicarbene Ligands for Enantioselective Rhodium-Catalyzed Hydroarylation of Terminal and Internal 1,3-Dienes with Indoles" is accepted to JACS. Congrats!
September 2017: Stephanie and Michael's paper on "Stereoselective Tandem Bis-Electrophile Couplings of Diborylmethane" is accepted to JACS. Congrats!
June 2017: Jake, Matt J, Stephanie and Joe’s paper on the enantioselective and diastereoselective synthesis of Hydroxy Bis(boronates) is accepted to ACS Catalysis. Congrats!
Synthetic Methods and Organometallic Catalysis at the University of North Carolina at Chapel Hill
Research in my group is involved with the discovery, design, and development of new chiral catalysts and catalytic methods for chemical synthesis. We focus on developing practical and effective catalysts that enable the use of simple and abundant starting materials for useful carbon-carbon and carbon-heteroatom bond forming reactions.
We are interested in understanding reaction mechanisms (efficiency and selectivity) as well as demonstrating and challenging our catalytic transformations (reliability) in efficient enantioselective total synthesis of complex biologically important molecules. Areas of interest include catalysis, stereoselective organic synthesis, and organometallic chemistry.