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1. eDNA in Environmental Monitoring and Biodiversity Analysis
eDNA (environmental DNA) are the traces of DNA that organisms leave behind in the environment, and which we can detect by using technologies in molecular biology. From this idea, we analyze eDNA as a powerful alternative of traditional sampling methods (e.g., netting) in various applications including biodiversity analysis and species detection.
2. Molecular Ecotoxicology
Molecular ecotoxicology is an interdisciplinary field that draws from knowledge and techniques in the fields of molecular biology, ecology, and toxicology to study the biological effects of environmental stressors. Our research mainly focuses on toxicity assessment and mode (or mechanism)-of-action investigation, particularly in marine zooplanktons. See below papers for the details.
Jeong et al., 2016. Microplastic size-dependent toxicity, oxidative stress induction, and p-JNK and p-p38 activation in the monogonont rotifer (Brachionus koreanus). Environ. Sci. Technol. 50, 8849-8857.
Jeong et al., 2018. Nanoplastic ingestion enhances toxicity of persistent organic pollutants (POPs) in the monogonont rotifer Brachionus koreanus via multixenobiotic resistance (MXR) disruption. Environ. Sci. Technol. 52, 11411-11418.
3. Novel Genes of Unknown Function
Animals have evolved independently depending on the phylogenetic place where they belong. Although most of gene families are conserved across the animal taxa, independent gene diversification has been always accompanied during evolution, resulting a novel function. Our goal is to identify and characterize function of novel genes in marine organisms by using genome resources and gene editing technologies (e.g., CRISPR/Cas9). This may provide a key insight into evolutionary understandings of marine life. See below papers for the details.
Jeong et al., 2020. Generation of albino via SLC45a2 gene targeting by CRISPR/Cas9 in the marine medaka Oryzias melastigma. Mar. Pollut. Bull. 154, 111038.
Jeong et al., 2017. ATP-binding cassette (ABC) proteins in aquatic invertebrates: evolutionary significance and application in marine ecotoxicology. Aquat. Toxicol. 185, 29-39.
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