RESEARCH & PUBLICATION
Selected Publications
Note: Asterisk (*) sign means the corresponding authorship.
1. Rashid PT, Hossain MJ*, Zahan MS, et al. Chemico-pharmacological and computational studies of Ophiorrhiza fasciculata D. Don and Psychotria silhetensis Hook. F. focusing cytotoxic, thrombolytic, anti-inflammatory, antioxidant, and anti-bacterial properties. Heliyon. 2023; 9(9); e20100. https://doi.org/10.1016/j.heliyon.2023.e20100
2. Khatun MCS, Muhit MA, Hossain MJ, et al. Isolation of phytochemical constituents from Stevia rebaudiana (Bert.) and evaluation of their anticancer, antimicrobial and antioxidant properties via in vitro and in silico approaches. Heliyon 2021; 7(12): e08475. https://doi.org/10.1016/j.heliyon.2021.e08475
3. Jannat T, Hossain MJ*, El-Shehawi AM, et al. Chemical and pharmacological profiling of Wrightia coccinea (roxb. Ex hornem.) sims focusing antioxidant, cytotoxic, antidiarrheal, hypoglycemic, and analgesic properties. Molecules. 2022; 27(13): 4024. https://doi.org/10.3390/molecules27134024
4. Farzana M, Hossain MJ*, El-Shehawi AM, et al. Phenolic constituents from Wendlandia tinctoria var. grandis (Roxb.) DC. Stem deciphering pharmacological potentials against oxidation, hyperglycemia, and diarrhea: phyto-pharmacological and computational approaches. Molecules. 2022; 27(18): 5957. https://doi.org/10.3390/molecules27185957
5. Sarwar S, Hossain MJ*, Irfan NM, et al. Renoprotection of selected antioxidant-rich foods (water spinach and red grape) and probiotics in gentamicin-induced nephrotoxicity and oxidative stress in rats. Life. 2022; 12(1): 60. https://doi.org/10.3390/life12010060
6. Mukta M, Hossain MJ*, Akter M, et al. Cardioprotection of water spinach (Ipomoea aquatica), wood apple (Limonia acidissima) and linseed (Linum usitatissimum L.) on doxorubicin-induced cardiotoxicity and oxidative stress in rat model. Nutr Metab Insights 2023; 10.1177/11786388231212116
7. Ripa FA, Hossain MJ*, Munira MS, et al. Phytochemical and pharmacological profiling of Trewia nudiflora Linn. leaf extract deciphers therapeutic potentials against thrombosis, arthritis, helminths, and insects. Open Chem. 2022; 20(1): 1304-12. https://doi.org/10.1515/chem-2022-0244
8. Hossain MJ, Sultan MZ, Rashid MA, Kuddus MR. Does rabeprazole sodium alleviate the anti-diabetic activity of linagliptin? drug-drug interaction analysis by in vitro and in vivo methods. Drug Res. 2020; 70(11): 519-27. DOI: 10.1055/a-1233-3371
9. Hossain MJ, Rashid MA, Sultan MZ. Transition metal chelation augments the half-life of secnidazole: molecular docking and fluorescence spectroscopic approaches. Drug Res. 2020; 70(12): 583-92. DOI: 10.1055/a-1252-2322
10. Hossain MJ, Rahman SA. Repurposing therapeutic agents against SARS-CoV-2 infection: most promising and neoteric progress. Expert Rev. Anti-Infect. Ther. 2021; 19(8): 1009-27. https://doi.org/10.1080/14787210.2021.1864327
11. Anjum N, Hossain MJ, Aktar F, et al. Potential in vitro and in vivo bioactivities of Schleichera oleosa (lour.) oken: A traditionally important medicinal plant of Bangladesh. Res J. Pharm. Technol. 2022;15(1):113-21. DOI: 10.52711/0974-360X.2022.00019
12. Rahman MM, Soma MA, Sultana N, Hossain MJ*. Exploring therapeutic potential of Woodfordia fruticosa (L.) Kurz leaf and bark focusing on antioxidant, antithrombotic, antimicrobial, anti-inflammatory, analgesic, and antidiarrheal properties. Health Sci. Rep. 2023, 6 (10): e1654. https://doi.org/10.1002/hsr2.1654
13. Ripa FA, Hossain MJ*, Nesa M, et al. Phytochemical and pharmacological profiling of Heritiera fomes Buch. Ham. deciphered thrombolytic, antiarthritic, anthelmintic, and insecticidal potentialities via in vitro approach. Evidence-Based Complement. Alternat. Med. 2022; 2022: 2594127. https://doi.org/10.1155/2022/2594127
14. Hoque N, Khan ZR, Rashid PT, Begum MN, Sharmin S, Hossain MJ et al. Antimicrobial, antioxidant, and cytotoxic properties of endophytic fungi isolated from Thysanolaena maxima Roxb., Dracaena spicata Roxb. and Aglaonema hookerianum Schott. BMC Complement Med Ther. 2023; 23(1): 347. https://doi.org/10.1186/s12906-023-04185-4
15. Das R, Rauf A, Mitra S, Emran TB, Hossain MJ, et al. Therapeutic potential of marine macrolides: An overview from 1990 to 2022. Chemico-Biological Interactions. 2022; 365:110072. https://doi.org/10.1016/j.cbi.2022.110072
16. Mitra S, Rauf A, Sutradhar H, Sadaf S, Hossain MJ, et al. Potential candidates from marine and terrestrial resources targeting mitochondrial inhibition: Insights from the molecular approach. Comp Biochem Physiol C. 2023; 264: 109509. https://doi.org/10.1016/j.cbpc.2022.109509
17. Hossain MJ*, Ahmmed F, Rahman SMA, et al. Impact of online education on fear of academic delay and psychological distress among university students following one year of COVID-19 outbreak in Bangladesh. Heliyon 2021; 7(6). e07388. https://doi.org/10.1016/j.heliyon.2021.e07388
18. Hossain MJ*, Jabin N, Ahmmed F, et al. Irrational use of antibiotics and factors associated with antibiotic resistance: Findings from a cross‐sectional study in Bangladesh. Health Sci. Rep. 2023; 6(8): e1465. https://doi.org/10.1002/hsr2.1465
19. Hossain MJ*, Ahmmed F, Khan MR, et al. Impact of prolonged covid-19 lockdown on body mass index, eating habits, and physical activity of university students in Bangladesh: a web-based cross-sectional study. Front. Nutr. 2022; 9. https://doi.org/10.3389/fnut.2022.873105
20. Hossain MJ*, Ahmmed F, Sarker MMR, et al. Factors associated with underprivileged e-Learning, session jam phobia, and the subsequent mental distress among students following the extended university closure in Bangladesh. Front. Public Health. 2022; 9: 2303. https://doi.org/10.3389/fpubh.2021.807474
21. Brishty SR, Hossain MJ, Khandaker MU, et al. A Comprehensive Account on Recent Progress in Pharmacological Activities of Benzimidazole Derivatives. Front Pharmacol. 2021; 12: 762807. doi: 10.3389/fphar.2021.762807
22. Das R, Mitra S, Tareq AM, Emran TB, Hossain MJ, et al. Medicinal plants used against hepatic disorders in Bangladesh: A comprehensive review. J Ethnopharmacol. 2022; 282: 114588. doi: 10.1016/j.jep.2021.114588.
23. Ghosh B, Rahman MM, Saha T, Hossain MJ*, Alam S, Al-Aman DAA, Kayser MS, Islam MS, Islam MK, Singh A, Ahmed T. Drinking Water Sources along the Banks of Buriganga River of Bangladesh are Polluted and Possess Serious Health Risks: A Comprehensive In Vivo Analysis. J Environ Public Health. 2023; 2023: 3369163. doi: 10.1155/2023/3369163.
24. Anjum J, …, Hossain MJ, Aljohani ASM, Abdulmonem WA, Alsharif KF, Alzahrani KJ, Khan H. A renewed concept on the MAPK signaling pathway in cancers: Polyphenols as a choice of therapeutics. Pharmacol Res. 2022; 184: 106398. doi: 10.1016/j.phrs.2022.106398.
25. Sultana A, Hossain MJ*, Kuddus MR, Rashid MA, Zahan MS, Mitra S, Roy A, Alam S, Sarker MMR, Naina Mohamed I. Ethnobotanical Uses, Phytochemistry, Toxicology, and Pharmacological Properties of Euphorbia neriifolia Linn. against Infectious Diseases: A Comprehensive Review. Molecules. 2022 ; 27(14): 4374. doi: 10.3390/molecules27144374.
26. Mitra S, …, Hossain MJ, Emran TB. Prospective multifunctional roles and pharmacological potential of dietary flavonoid narirutin. Biomed Pharmacother. 2022; 150: 112932. doi: 10.1016/j.biopha.2022.112932.
27. Hossain MJ, Rabaan AA, Mutair AA, Alhumaid S, Emran TB, Saikumar G, Mitra S, Dhama K. Strategies to tackle SARS-CoV-2 Mu, a newly classified variant of interest likely to resist currently available COVID-19 vaccines. Hum Vaccin Immunother. 2022; 18(1): 2027197. doi: 10.1080/21645515.2022.2027197.
28. Bari MS, Hossain MJ*, Ahmmed F, Sarker MMR, Khandokar L, Chaithy AP, Aziz F, Mitra S, Emran TB, Islam MS, Islam MR, Mohamed IN. Knowledge, Perception, and Willingness towards Immunization among Bangladeshi Population during COVID-19 Vaccine Rolling Period. Vaccines (Basel). 2021 Dec 7;9(12):1449. doi: 10.3390/vaccines9121449.
29. Tallei TE,…,Hossain MJ, Emran TB. Fruit Bromelain-Derived Peptide Potentially Restrains the Attachment of SARS-CoV-2 Variants to hACE2: A Pharmacoinformatics Approach. Molecules. 2022 Jan 1;27(1):260. doi: 10.3390/molecules27010260.
30. Alam S, …, Hossain MJ, Kim JK, Kim B, Hasib MS, Zihad SMNK, Haque MR, Mohamed IN, Rashid MA. Antidiabetic Potential of Commonly Available Fruit Plants in Bangladesh: Updates on Prospective Phytochemicals and Their Reported MoAs. Molecules. 2022 Dec 8;27(24):8709. doi: 10.3390/molecules27248709.
31. Akash S, …, Hossain MJ, Rashid MA, Kumer A, Ghosh A, León-Figueroa DA, Barboza JJ, Padhi BK, Sah R. Modified coptisine derivatives as an inhibitor against pathogenic Rhizomucor miehei, Mycolicibacterium smegmatis (Black Fungus), Monkeypox, and Marburg virus by molecular docking and molecular dynamics simulation-based drug design approach. Front Pharmacol. 2023 Apr 19;14:1140494. doi: 10.3389/fphar.2023.1140494.
32. Amee KN,…., Hossain MJ, Hasan R, Sarker MM. Phytochemical Profiling and Evaluation for Anti-oxidant, Thrombolytic, and Antimicrobial Activities of Moringa oleifera Lam Leaves Extracts. Biomedical & Pharmacology Journal. 2023 Jun;16(2):1027-36. https://dx.doi.org/10.13005/bpj/2684
33. Hossain MJ*, Ahmmed F, Khandokar L, Rahman SMA, Hridoy A, Ripa FA, Emran TB, Islam MR, Mitra S, Alam M. Status of psychological health of students following the extended university closure in Bangladesh: Results from a web-based cross-sectional study. PLOS Glob Public Health. 2022 Mar 31;2(3):e0000315. doi: 10.1371/journal.pgph.0000315.
34. El-Mageed HA, …, Hossain MJ, Capasso R, Emran TB. In silico evaluation of different flavonoids from medicinal plants for their potency against SARS-CoV-2. Biologics. 2021; 1(3): 416-34. DOI: https://doi.org/10.3390/biologics1030024
35. Uddin TM,…, Hossain MJ, Koirala N. Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects. J Infect Public Health. 2021; 14(12): 1750-1766. doi: 10.1016/j.jiph.2021.10.020.
Notable conference presentation/talk
§ Hossain MJ. In-vitro, in-vivo and in-silico profiling of Foeniculum vulgare (fennel seed) provided pharmacological potentialities against oxidation, inflammation, pain and diarrhea. ICPS-2023 (May 11-12, 2023), Dhaka, Bangladesh.
§ Hossain MJ. Antimicrobial resistance: a global concern and its tackling strategy through antimicrobial natural products. Biannual Faculty Development Program (FDP). State University of Bangladesh (Dec 17, 2022).
- Poster presentations
Mamtaz Farzana, Md. Jamal Hossain, Md. Al Amin Sikder, Mohammad Sharifur Rahman, and Mohammad A. Rashid. Phenolic Constituents from Wendlandia tinctoria var. grandis (Roxb.) DC. Stem Deciphering Pharmacological Potentials against Oxidation, Hyperglycemia, and Diarrhea: Phyto-Pharmacological and Computational Approaches. Dhaka University Research-Publication Fair 2022. Link for download: https://drive.google.com/file/d/1GaV3MuxPw-NyXzVFCueudWCV0J4KP2YS/view?usp=sharing
Hossain et al. Molecular docking, drug-likeness, and in-silico pharmacokinetics and toxicity studies of phytoconstituents derived from Euphorbia neriifolia Linn. against bacterial infection. Link: https://www.researchgate.net/publication/373096849_Molecular_docking_drug-likeness_and_in-silico_pharmacokinetics_and_toxicity_studies_of_phytoconstituents_derived_from_Euphorbia_neriifolia_Linn_against_bacterial_infection
Hossain et al. Computational docking, drug-likeness, and in-silico ADMET analysis of bioactive compounds derived from Euphorbia neriifolia L. in quest of new therapeutic potentiality against influenza virus. Link: https://www.researchgate.net/publication/373096843_Computational_docking_drug-likeness_and_in-silico_ADMET_analysis_of_bioactive_compounds_derived_from_Euphorbia_neriifolia_L_in_quest_of_new_therapeutic_potentiality_against_influenza_virus
- RESEARCH EXPERIENCES
Research Interests
Phytochemistry: In vitro, In vivo & In silico investigations
Organic synthetic medicinal chemistry & analytical chemistry
Drug discovery and computational study
In vitro & in vivo drug-drug and drug-protein interactions study
Spectroscopy, chromatography, and thermodynamics
Public health & pharmacy practice
Current research and COVID-19's project
A survey study on "Antibiotic Misuse and Its Resistance Pattern: Dhaka University Experiences".
Treatment guidelines of cancer patients infected by SARS-CoV-2: A systematic study
KAB toward COVID-19 of BD populations: A systematic review
Transition metal complexation: Synthesis, characterizations, Forced degradation studies, and evaluation of various pharmacological activities to quest new therapeutic effects or enhance potency.
Drug-drug complexation studies to find out the synergistic effects or to be established as repurposed drugs.
Thermodynamic analysis, spectroscopic and computational-based molecular docking studies of some pure compounds and synthetic molecules.
Drug-drug Interaction analysis by fluorescence spectroscopic, and molecular docking strategies.
RP-HPLC and UV-Vis spectroscopic method development and validation.
M. Pharm Thesis
Topic: Drug-Drug and Drug-Metal Complexations: Synthesis, Characterization, Forced degradation studies, and Evaluation of Biological Activities in Quest of New Therapeutic Possibilities.
Drug-drug interaction analysis between linagliptin and rabeprazole sodium by in vitro and in vivo methods.
Transition metal complexation of secnidazole: Synthesis, characterizations and evaluation of various pharmacological activities to explore new therapeutic possibilities.
Forced degradation studies under USP guidelines and analytical method validations to establish the stability-indicating parameters/conditions.
B. Pharm project research
Review on Cephalosporin Resistance and its Concurrence.
Establishment of some plausible mechanisms to avert antibiotic resistance.
- Important links
ORCID iD: https://orcid.org/0000-0001-9706-207X