Publications

24. Lee YJ#, Lee SY#, Kim S#, Kim SH, Lee SH, Park S, Kim JJ*, Kim DW*, Kim H*. (# Co-first author, * Co-correspondence) REXO5 Promotes Genomic Integrity Through Regulating R-loop Using Its Exonuclease Activity. Leukemia (2024)

23. Lee SY*, Lee SH, Choi NH, Kim JY, Kweon JH, Miller KM, Kim JJ*. (* Co-correspondence) PCAF promotes R-loop resolution via histone acetylation. Nucleic Acids Research (2024) Jun 28:gkae558.  This paper has been selected to NAR Breakthrough Article

22. Lee SY, Miller KM, Kim JJ*. (* Correspondence) Clinical and Mechanistic Implications of R-Loops in Human Leukemias. Int J Mol Sci. (2023) Mar 22;24(6):5966.

21.  Lee SY, Kim JJ*, Miller KM*. (* Co-correspondence) Single-Cell Analysis of Histone Acetylation Dynamics at Replication Forks Using PLA and SIRF. Methods Mol. Biol. (2023) 2589:345-360.

20. McCann JL#, Cristini A#, Law EK, Lee SY, Tellier M, Carpenter MA, Beghè C, Kim JJ, Sanchez A, Jarvis MC, Stefanovska B, Temiz NA, Bergstrom EN, Salamango DJ, Brown MR, Murphy S, Alexandrov LB, Miller KM*, Gromak N*, Harris RS*. (# Co-first author, ## Co-2nd author, * Co-correspondence) APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer. Nature Genetics. (2023) Oct;55(10):1721-1734.

19. Kim JJ*, Lee SY*, Hwang Y*, Kim S*, Chung JM, Park S, Yoon J, Yun H, Ji JH, Chae S, Cho H, Kim CG, Dawson TM, Kim H#, Dawson VL#, Kang HC#. USP39 promotes non-homologous end-joining repair by poly(ADP-ribose)-induced liquid demixing. Nucleic Acids Research (2021) Oct 6:gkab892. . (* Co-first author, #Co-corespondence)

18. Lee SY, Kim JJ*, Miller KM*.Bromodomain proteins: protectors against endogenous DNA damage and facilitators of genome integrity. Experimental and Molecular Medicine (2021) Sep;53(9):1268-1277. (* Co-correspondence)

17. Ren W#, Fan H#, Grimm SA, Kim JJ, Li L, Guo Y, Petell CJ, Tan XF, Zhang ZM, Coan JP, Yin J, Kim DI, Gao L, Cai L, Khudaverdyan N, Çetin B, Patel DJ, Wang Y, Cui Q, Strahl BD, Gozani O, Miller KM, O'Leary SE, Wade PA, Wang GG*, Song J*. DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation. Nature communications (2021) May 3;12(1):2490. (# Co-first author, * Co-correspondence)

16. Lee SY*, Kim JJ*, Miller KM. Emerging Roles of RNA Modifications in Genome Integrity. Briefings in Functional Genomics (2021) Mar 27;20(2):106-112 (* Co-first author)

15. Kim JJ*, Lee SY*,Choi JH, Woo HG, Xhemalce B, Miller KM. PCAF-mediated histone acetylation promotes replication fork degradation by MRE11 and EXO1 in BRCA-deficient cells. Molecular Cell (2020) Oct 15;80(2):327-344.e8. (* Co-first author)

14. Ren W*, Fan H*, Grimm SA, Guo Y, Kim JJ, Li L, Petell CJ, Tan XF, Zhang ZM, Coan JP, Yin J, Gao L, Cai L, Detrick B, Cetin B, Wang Y, Cui Q, Strahl BD, Gozani O, Miller KM, O’Leary SE, Wade PA, Patel DJ, Wang GG, Song J. Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation. Proc. Natl. Acad. Sci. USA (2020) Aug 4;117(31):18439-18447. (* Co-first author)

13. Kim JJ*, Lee SY*, Gong F, Battenhouse AM, Boutz DR, Bashyal A, Refvik ST, Chiang CM, Xhemalce B, Paull TT, Brodbelt JS, Marcotte EM, Miller KM. Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity. Genes & Development (2019) Dec 1;33(23-24):1751-1774. (* Co-first author)

12. Kim JJ*, Lee SY*, Miller KM. Preserving Genome Integrity and Function: The DNA Damage Response and Histone Modifications. Crit. Rev. Biochem. Mol. Biol. (2019) Jun 4; 54(3):208-241. (* Co-first author)

11. Kim JJ, Kumbhar R, Gong F, Miller KM. In Time and Space: Laser Microirradiation and the DNA Damage Response. Methods Mol. Biol. (2019);1999:61-74.

10. Kim JJ*, Lee SY*, Kim S, Chung JM, Kwon M, Yoon JH, Park S, Hwang Y, Park D, Lee JS, Kang HC. A Novel Reciprocal Crosstalk between RNF168 and PARP1 to Regulate DNA Repair Processes. Mol. Cells (2018) Aug 31;41(8):799-807. (* Co-first author)

9. Kim JH, Moon SH, No M, Kim JJ, Choi EJ, Cho BJ, Kim JS, Kim IH, Kim IA. Isotype-specific Inhibition of Histone Deacetylases: Identification of Optimal Targets for Radiosensitization. Cancer Res. Treat. (2016) Jul;48(3):1130-40.

8. Kim YP*, Park D*, Kim JJ*, Chi WJ, Lee SH, Lee SY, Kim S, Chung JM, Jeon J, Lee BD, Shin JH, Lee YI, Cho H, Lee JM, Kang HC. Effective therapeutic approach for head and neck cancer by an engineered minibody targeting the EGFR receptor. PLoS ONE (2014) 1;9(12):e113442. (* Co-first author)

7. Nguyen TT, Kim YM, Kim TD, Le OT, Kim JJ, Kang HC, Hasegawa H, Kanaho Y, Jou I, Lee SY. Phosphatidylinositol 4-phosphate 5-kinase α facilitates Toll-like receptor 4-mediated microglial inflammation through regulation of the Toll/interleukin-1 receptor domain-containing adaptor protein (TIRAP) location. J. Biol. Chem. (2013) Feb 22;288(8):5645-59.

6. Yang H, Ko HJ, Yang JY, Kim JJ, Seo SU, Park SG, Choi SS, Seong JK, Kweon MN. Interleukin-1 promotes coagulation, which is necessary for protective immunity in the lung against Streptococcus pneumoniae infection. J. Infect. Dis. (2013) Jan 1;207(1):50-60.

5. Jiang J, Kim JJ, Kim DY, Kim MK, Oh NH, Koppula S, Park PJ, Choi DK, Shin YK, Kim IH, Kang TB, Lee KH. Acorus gramineus inhibits microglia mediated neuroinflammation and prevents neurotoxicity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse model of Parkinson's disease. J. Ethnopharmacol. (2012) Dec18;144(3):506-13.

4. Seo SU, Kim JJ, Yang H, Kwon HJ, Yang JY, Curtiss Iii R, Kweon MN. Effective protection against secondary pneumococcal pneumonia by oral vaccination with attenuated Salmonella delivering PspA antigen in mice. Vaccine (2012) Nov 6;30(48):6816-23.

3. Kim JJ*, Jiang J*, Shim DW, Kwon SC, Kim TJ, Ye SK, Kim MK, Shin YK, Koppula S,Kang TB, Choi DK, Lee KH. Anti-inflammatory and anti-allergic effects of Agrimonia pilosa Ledeb extract on murine cell lines and OVA-induced airway inflammation. J.Ethnopharmacol. (2012) Mar 27; 140(2):213-21. (* Co-first author)

2. Ma JS, Kim WJ, Kim JJ, Kim TJ, Ye SK, Song MD, Kang H, Kim DW, Moon WK, Lee KH. Gold nanoparticles attenuate LPS-induced NO production through the inhibition of NF-kappaB and IFN-beta/STAT1 pathways in RAW264.7 cells. Nitric Oxide (2010) Nov 1;23(3):214-9.

1. Oh JS*, Kim JJ*, Byun JY*, Kim IA. Lin28-let7 modulates radiosensitivity of human cancer cells with activation of K-Ras. Int. J. Radiat. Oncol. Biol. Phys. (2010) Jan 1;76(1):5-8. (* Co-first author)