Matthew A. Cruz

Currently, I am a PhD candidate in Greg R. Bowman's lab at the University of Pennsylvania.  For my thesis I am exploring the links between protein-dynamics and protein function using a combination of experimental and computational biophysics. In my free time I like to read, ride my bike or go camping, journal about life, watch TV (scifi series or reality TV usually), and cook.

Publications of Interest:

• Cruz, M.A., Frederick, T.E., Mallimadugula, U.L. et al. A cryptic pocket in Ebola VP35 allosterically controls RNA binding. Nat Commun 13, 2269 (2022). https://doi.org/10.1038/s41467-022-29927-9 

• Joseph S. Xu, Madeline N. Hewitt, Jaskeerat S Gulati, Matthew A Cruz, Hongli Zhan, Shirley Liu, Kathleen S. Matthews, "Lactose Repressor Hinge Domain Independently Binds DNA." Protein Sci. 2018, 27, 839−847. doi: https://doi.org/10.1002/pro.3372