Methods: We reviewed clinical charts to identify inpatients with an ADR as one of the admitting diagnoses and, if so, whether or not the hospital admission was primarily attributed to the ADR. Logistic regression was used to determine factors associated with hospital admissions primarily attributed to ADRs.
Results: Among 762 inpatients, 14% had ADRs at hospital admission and 7% were primarily hospitalized due to ADRs. A total of 235 ADRs occurred among all inpatients and 57% of the ADRs were the primary diagnosis linked to hospital admission. The majority of ADRs occurred in people living with HIV and were attributed to antiretroviral drugs. HIV infection [aOR (adjusted odds ratio) = 2.97, 95% confidence interval (CI): 1.30-6.77], use of antiretroviral therapy (aOR = 5.46, 95% CI: 2.56-11.68), self-medication (aOR = 2.27, 95% CI: 1.14-4.55) and higher number of drugs used (aOR = 1.13, 95% CI: 1.01-1.26) were independently associated with hospital admissions attributed to ADRs.
Conclusion: Antiretroviral drugs were often implicated in ADR-related hospital admissions. HIV infection (whether managed by antiretroviral therapy or not), self-medication and high pill burden were associated with hospital admissions attributable to ADRs. The high HIV burden in Sub-Saharan Africa increases the risk of ADR-related hospitalization implying the need for emphasis on early detection, monitoring and appropriate management of ADRs associated with hospital admission in people living with HIV.
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While meeting a team from the Education Review Commission led by the chairperson, Col (Rtd) Amanya Mushega at the university yesterday, Prof Nawangwe said undergraduate admissions will be slashed with effect from next year.
Other recommendations included redesigning the university curriculum to suit local needs, digitalising teaching and learning, doing the training in soft skills compulsory, and appreciating the role of humanities in dealing with societal problems.
A document from the office of the academic registrar shows among other things that the university is recalling adverts for the said programme and advising applicants for private sponsorship to amend their application with other choices available.
Makerere University has received warnings from East African Community (EAC) Medical and Dental Practitioners Boards and Councils since 2016 directing the institution to halt admissions for the Dental surgery programme over inadequate teaching equipment, space, and low staff to student ratio.
However, Professor Umar Kakumba, the Deputy Vice-Chancellor in-Charge of Academic Affairs, notes that the university is trying to meet the set standards by putting up a full-fledged dental clinic and recruited more staff to ensure that they meet the recommended lecturer to student ratio of 1:4.
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