Maddux Lab
Human Evolutionary Anatomy
Human Evolutionary Anatomy
The Maddux Lab is housed in the Center for Anatomical Sciences, a division of the Department of Physiology and Anatomy at the University of North Texas Health Science Center in Fort Worth, Texas.
Research in the Maddux Lab focuses on later phases of human evolution with an emphasis on the distinctive craniofacial morphologies of Neandertals and modern humans.
Current projects focus extensively on linking evolutionary changes in upper respiratory tract anatomy to physiological demands for respiratory air-conditioning (heat and moisture transfer) in different climates. In particular, the laboratory specializes in 3D modeling and geometric morphometric analysis of upper respiratory tract anatomy using high-resolution medical imaging modalities (e.g., CT, μCT, MRI).
Research in the Maddux lab is supported by the National Science Foundation, Leakey Foundation, Wenner-Gren Foundation, Texas Center for Health Disparities, and the American Association for Anatomy.
Associate Professor
Center for Anatomical Sciences
University of North Texas Health Science Center
Ft. Worth, TX 76107
News
Congratulations to PhD candidate Baonhu Tran for receiving a Research Grant from the Leakey Foundation in support of her Dissertation project:
"Experimentally re-evaluating the role of the respiratory system in human thermoregulatory adaptation"
Congratulations to PhD candidate Baonhu Tran for receiving a Dissertation Fieldwork Grant from the Wenner-Gren Foundation in support of her Dissertation project:
"Reevaluating the role of the respiratory system in human thermoregulation and climatic adaptation"
Congratulations to MS student Caroline Counts for successfully defending her MS Thesis:
"Investigating variation in human body composition: A comparison of CT and DEXA imaging modalities"
Maddux Lab presentations at the 94th Annual Meeting of the American Association of Biological Anthropologists (AABA) in Baltimore, MD.
Butaric, L.N., C.N. Nicholas, S.D. Maddux. Upper respiratory ontogeny and integration among human subadults. American Journal of Biological Anthropology 186(S79): 23
Hoskins, M., M.A. Goodstein, C. Counts, L.A. Ward, E.O. Cho, L. Cowgill, S.D. Maddux. 3D scanning and precision anthropometry of human body surface area: Implications for thermoregulatory research. American Journal of Biological Anthropology 186(S79): 75-76
Kelly, A.P., I. Nebeker, F. Savoldi, J. Tsoi, M. Rivera, A. Yeung, S.D. Maddux. Effect of climate and energetics with Southeast Asian nasal morphology. American Journal of Biological Anthropology 186(S79):84
Tran, B., L.A. Ward, A. Reif, C. Boettger, L.W. Cowgill, C. Ocobock, E.O. Cho, S.D. Maddux. Experimentally re-evaluating respiratory contributions to total body heat loss. American Journal of Biological Anthropology 186(S79): 167
Ward, L.A., S.D. Maddux. L.W. Cowgill, C. Ocobock, E.O. Cho. Experimentally assessing association between nasal morphology, climate, and minute ventilation. American Journal of Biological Anthropology 186(S79): 175
Congratulations to PhD candidate Lyndee Ward for receiving a Research Grant from the National Science Foundation (BCS Biological Anthropology #2419511) in support of her Dissertation project:
"Doctoral Dissertation Research: Nasal morphological responses to thermal and exertional conditions"
Maddux Lab SOAR intern, Michelle Hoskins (UT - Arlington), presented her research at the 2024 UNTHSC Summer Research Internship Program conference.
3D Scanning and Precision Anthropometry of Human Body Surface Area:
Implications for Thermoregulatory Research.
Hoskins, M., Goodstein, M., Ward, L.A., Cho, E.O., Ocobock, C., Cowgill, L., Maddux, S.D.
Congratulations to PhD candidate Lyndee Ward for receiving a Research Grant from the Leakey Foundation in support of her Dissertation project:
"Climate and human nasal evolution: Experimentally investigating skeletal and soft-tissue influences on nasal airflow dynamics in living humans"
Congratulations to MS student Chloe Boettger for successfully defending her MS practicum "Assessment of digit skin temperatures via infrared thermography under different climatic conditions"
Congratulations to PhD students Lyndee Ward and Baonhu Tran for winning student presentation awards at the 93nd Annual Meeting of the American Association of Biological Anthropologists (AABA) in Los Angeles, CA.
Lyndee Ward - AABA Outstanding Student Presentation Award
Baonhu Tran - AABA-AAA "Anatomy in Anthropology" Student Presentation Award
Maddux Lab presentations at the 93rd Annual Meeting of the American Association of Biological Anthropologists (AABA) in Los Angeles, CA.
Tran, B., L.A. Ward, H.H.K. Patabendige, V.C. Nair, E.O. Cho, T.R. Yokley, B.H. Dennis, S.D. Maddux. Asymmetrical heat and moisture exchange during the nasal cycle: Investigating the influence of mucosal congestion on human nasal form and function. American Journal of Biological Anthropology 183(S77): 181
Ward, L.A., H.H.K. Patabendige, V.C. Nair, D.R. Mitchell, E.O. Cho, T.R. Yokley, B.H. Dennis, S.D. Maddux. Deconstructing human nasal adaptation: An iterative assessment of morphological influences on intranasal air conditioning in two and three dimensions. American Journal of Biological Anthropology 183(S77): 192
Goodstein, M., A. Reif, L.A. Ward, E.O. Cho, C. Ocobock, L. Cowgill, S.D. Maddux. Quantifying human body surface area: A comparison of photogrammetry and CT scanning to estimation techniques. American Journal of Biological Anthropology 183(S77): 61
Reif, A., M. Goodstein, L.A. Ward, E.O. Cho, C. Ocobock, L. Cowgill, S.D. Maddux. Variation in body composition in relation to evolutionary models of human thermoregulation. American Journal of Biological Anthropology 183(S77): 146
Thompson, I., B. Perchalski, S.D. Maddux, L.A. Gonzales. Identification of ecological, locomotor, and morphological indicators of semi-terrestrially in anthropoid primates. American Journal of Biological Anthropology 183(S77): 178-179
Congratulations to PhD candidate Lyndee Ward for receiving an NIH training fellowship through the Artificial Intelligence/Machine Learning Consortium (AIM-AHEAD) & All of Us Research Program.
Congratulations to PhD candidate Lyndee Ward and MS student Caroline Counts for winning student presentation awards at the 17th Annual Meeting of the Texas Association of Biological Anthropologists (TABA).
Lyndee Ward - 2nd Place PhD student podium presentation
Caroline Counts - 1st Place MS student poster presentation
Maddux Lab presentations at TABA 2023
Modeling airflow dynamics during the nasal cycle in silico: Implications for variation in human nasal form and function. Baonhu Tran, Lyndee A. Ward, Hasintha H.A.K. Patabendige, Vivek C. Nair, Elizabeth O. Cho, Todd R. Yokley, Brian H. Dennis, Scott D. Maddux
Thermoregulatory implications of sexual dimorphism in human torso morphology. Caroline Counts, Katherine McBroom, Chloe Boettger, Elizabeth O. Cho, Albert Yurvati, Cara Ocobock, Libby Cowgill, Scott D. Maddux
Climatic adaptation in the human nose: An investigation using 3D morphometrics and computational fluid dynamics. Lyndee A. Ward, Hasintha H.A.K Patabendige, Elizabeth O. Cho, Todd R. Yokley, Brian H. Dennis, Scott D. Maddux
New Grant
Bridging clinical and environmental research using environmental chambers. Louisiana Clinical & Translational Sciences Center (LA CaTS) – Visiting Scholars Program. A.M. Niclou, Principal Investigator; S.D. Maddux, L. Redman, Co-Sponsors.
Elizabeth Cho, PhD hired as an Assistant Professor at UNTHSC
Congratulations to Maddux Lab postdoctoral fellow, Dr. Elizabeth Cho, who has accepted a tenure-track faculty position in the Center for Anatomical Sciences at UNTHSC.
Dr. Cho's new faculty webpage can be viewed here: https://www.unthsc.edu/center-for-anatomical-sciences/elizabeth-cho/
Maddux Lab SOAR interns, Ana Reif (Columbia Univ.) and Miranda Goodstein (Tufts Univ.), present their research at the 2023 UNTHSC Summer Research Internship Program conference.
The relevance of body composition to evolutionary models of human thermoregulation.
Reif, A., Goodstein, M., Ward, L.A., Cho, E.O., Ocobock, C., Cowgill, L., Maddux, S.D.,
Quantifying human body surface area: A comparison of photogrammetry and CT scanning to estimation techniques.Goodstein, M., Reif, A., Ward, L.A., Cho, E.O., Ocobock, C., Cowgill, L., Maddux, S.D.,
The Maddux Lab welcomes new MS student, Chloe Boettger, to the lab!
Chloe is a second-year research track Master's of Medical Sciences student at UNTHSC. Her research project focuses on the use of thermal imaging to assess differences between skin and core temperatures during climatic exposures in the environmental chamber.
Congratulations to Dr. Alexa Kelly on the conferral of her PhD at UNTHSC's 2023 commencement ceremony!
Congratulations to Alexa Kelly on being awarded the 2023 School of Biomedical Sciences Dean's Award for Scholarly Excellence!
Maddux Lab presentations at the 92nd Annual Meeting of the American Association of Biological Anthropologists (AABA) in Reno, NV.
Cho, E.O., L.N. Butaric, S.D. Maddux. One of these is not like the others: Re-evaluating the association of nasal projection with climate. American Journal of Biological Anthropology. 2023. 180(S75): 31
Kelly, A.P., S.D. Maddux. Testing the Respiratory-Energetics Hypothesis: An investigation of metabolic demands and nasal size across human populations. American Journal of Biological Anthropology. 2023.180(S75): 89
Tran, B., L.A. Ward, H.H.K. Patabendige, V.C. Nair, E.O. Cho, T.R. Yokley, B.H. Dennis, S.D. Maddux. Modeling airflow during the nasal cycle in 3D: Implications for variation in human nasal form and function. American Journal of Biological Anthropology. 2023. 180(S75): 177-178
Ward, L.A., H.H.K. Patabendige, V.C. Nair, D.R. Mitchell, E.O. Cho, T.R. Yokley, B.H. Dennis, S.D. Maddux. Anthroengineering and the human nose: Investigating climatic adaptation using 3D morphometrics and computational fluid dynamics. American Journal of Biological Anthropology. 2023. 180(S75): 190
Congratulations to former PhD student, Dr. Alexa Kelly, on her first day as a tenure-track Assistant Professor in the Department of Anatomy at Campbell University in North Carolina!
Faculty Profile: Alexa Kelly
Congratulations to Dr. Alexa Kelly on the successful defense of her PhD dissertation "The interactive influence of climate and energetics on human nasal morphology."
New Publication:
Kelly, A. P., Ocobock, C., Butaric, L. N., & Maddux, S. D. (2023). Metabolic demands and sexual dimorphism in human nasal morphology: A test of the respiratory‐energetics hypothesis. American Journal of Biological Anthropology, 180(3), 453-471.
Maddux Lab presentations at the 16th Annual meeting of the Texas Association of Biological Anthropologists (TABA) in Austin, TX
An in silico method for modeling nasal congestion: Implications for assessing ecogeographic variation in human nasal form and function. Baonhu Tran, Lyndee A. Ward, Elizabeth Thai, Scott D. Maddux
Three-dimensional morphometric assessment of ecogeographic variation in the soft-tissue nasal airway. Lyndee A. Ward, Elizabeth Thai, Todd R. Yokley, Scott D. Maddux
Assessing covariation of neurocranial and nasal morphology in relation to climate. Alyssa Loredo, Hannah Oliver, Lyndee A. Ward, Elizabeth O. Cho, Scott D. Maddux
Skeletal variation in East Asian populations: Evaluating the influence of precipitation and humidity. Elizabeth O. Cho, Libby W. Cowgill, Gregory E. Blomquist
New Publication:
Kim, S., Ward, L. A., Butaric, L. N., & Maddux, S. D. (2022). Human maxillary sinus size, shape, and surface area: Implications for structural and functional hypotheses. American Journal of Biological Anthropology, 179(4), 640-654.
The Maddux Lab welcomes new PhD student, Baohu Tran, to the lab!
Baonhu received her BA in Anthropology from the University of Texas at Arlington in May 2022. A former SOAR intern at UNTHSC, Baonhu's research interests center around climatic adaptation in respiratory anatomy during human evolution.
Baonhu is a 2022 Fellow of the NSF Graduate Research Fellowship Program (GRFP).
Tenure!
Scott was promoted to Associate Professor with tenure. Thanks to everyone who came out to celebrate at the UNTHSC promotion and tenure event!
Congratulations to Alexa Kelly on being awarded the Sandy C. Marks Jr. Student Poster Presentation Award at the 2022 Annual Meeting of the AACA!
Maddux Lab presentations at the 2022 Annual Meeting of the American Association of Clinical Anatomists (AACA) in Fort Worth, TX
Cho, E.O., L.A. Ward, H.H.K. Patabendige, B.H. Dennis, S.D. Maddux. Nasal Morphology and Respiratory Airflow Physiology: Implications for Health Disparities in Asthma. Clinical Anatomy 35(6): 61
Kelly, A.P., S.D. Maddux. Nasal morphology and energetic demands: A test of the respiratory energetics hypothesis. Clinical Anatomy 35(6): 46
Warner, A.A., A.P. Kelly, S.D. Maddux. Virtual Reconstruction of 3D Skeletal Anatomy: A Comparison of Two Methodologies. Clinical Anatomy 35(6): 71
Congratulations to Dr. Suhhyun 'Sarah' Kim on the conferral of both her DO and PhD degrees at UNTHSC's 2022 commencement ceremony!
New Grant:
Climatic adaptation and the human nose: An experimental investigation in living humans. National Science Foundation. SBE – Postdoctoral Research Fellowship Program, #2203808. E.O. Cho, Principal Investigator; S.D. Maddux, Lead Sponsor; C. Ocobock, B. Dennis, Co-Sponsors. $138,000.
NSF News Release: SBE supports early-career scientists with 25 new postdoctoral fellowship awards
Congratulations to Dr. Suhhyun 'Sarah' Kim on the successful defense of her PhD dissertation: "Three-dimensional variation in maxillary sinus anatomy: Implications for health disparities in Sinonasal disease."
Maddux Lab presentations at the 91st Annual Meeting of the American Association of Biological Anthropologists (AABA) in Denver, CO.
Cowgill, L.W., S.D. Maddux, C. Ocobock. Revisiting the thermoregulatory imperative in living humans. American Journal of Biological Anthropology 177(S73):30
Kim, S., L.N. Butaric, S.D. Maddux. Allometric scaling of maxillary sinus volume in modern humans. American Journal of Biological Anthropology 177(S73):97
Tran, B., L.A. Ward, E.Thai, S.D. Maddux. An in silico method for modeling the nasal cycle in 3D: Implications for assessing human nasal form and function. American Journal of Biological Anthropology 177(S73):184
Congratulations to DO/PhD student, Sarah Kim, for matching into the Anatomical and Clinical Pathology Residency program at the University of Washington in Seattle (her first choice).