If you want a mixer for live sound, recording, and content creation for remote work, choose Mackie ProFX16v3; if you need open-back reference headphones for focused listening, choose Audio-Technica ATH-R50x. These products solve different problems: one handles multiple audio sources, while the other is a wired listening tool.
For a remote-work setup with a microphone and several audio sources to manage, the Mackie is the more capable hub. For evaluating audio through headphones, the ATH-R50x is the more focused choice.
• Mackie ProFX16v3 strength: 16 channels, built-in effects, and USB recording; trade-off: it is a mixer, not a direct substitute for dedicated reference headphones.
• Audio-Technica ATH-R50x strength: lightweight open-back headphones with a 5 Hz–40,000 Hz response; trade-off: they are wired and do not provide a mixer’s input routing or effects.
• Mackie is for: people who need to mix, record, or create with multiple audio sources.
• Audio-Technica is for: people who want detailed, natural-sounding headphone monitoring and already have a compatible audio source.
• For remote work: choose based on the task—managing audio inputs points to Mackie; listening critically points to Audio-Technica.
The Mackie ProFX16v3 is a 16-channel, 4-bus effects mixer built for live mixing, home recording, and content creation. Its Onyx mic preamps provide 60 dB of headroom, and its 24 built-in effects give you options for shaping sound within the mixer. That makes it a practical choice when a simple headphone connection is not enough and you need to manage multiple sources.
For recording, it supports 24-bit/192 kHz capture through 2x4 USB I/O and includes zero-latency hardware monitoring. In a remote-work setting, those features are relevant if your setup involves several audio sources, recording, or content creation alongside calls. It is not, however, a headset or a standalone pair of reference headphones. The bundle includes closed-back Tascam TH-02 headphones and a hard case, but the mixer is the core tool.
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We compare products from their published specs and features; the verdicts below are our independent editorial opinions.
Updated: 2026-10-23 · 6 min read · Independent comparison
The ATH-R50x is a wired, over-ear pair of open-back reference headphones. Its 45 mm drivers are designed for natural listening, and the stated frequency response runs from 5 Hz to 40,000 Hz. The 50-ohm impedance is intended to work with standard audio interfaces, laptops, and mobile devices without requiring a dedicated high-power amplifier.
Its open-back design allows airflow through the earcups and is intended to create a transparent, spacious listening presentation. The lightweight 207 g construction, padded headband, and breathable velour earpads suit longer listening sessions. Two detachable locking cables are included: one 3.0 m and one 1.2 m, both with 3.5 mm plugs and 1/4-inch adapters. Those details make it flexible for desk listening and audio work, though it remains a wired headphone with no noise-control feature.
For remote work, this can make sense when your priority is hearing audio clearly from a compatible computer or interface. But open-back headphones are not a closed, isolating headset: sound can pass between the earcups and the room, so they may be a poor fit if you need to keep your listening private or block surrounding noise. They also do not replace a mixer when you need to combine or route several inputs.
• Best for mixing multiple sources → Mackie ProFX16v3. It provides 16 channels and a 4-bus mixer design; the ATH-R50x is for listening, not input mixing.
• Best for USB recording → Mackie ProFX16v3. Its 2x4 USB I/O supports recording at 24-bit/192 kHz, with zero-latency hardware monitoring.
• Best for built-in effects → Mackie ProFX16v3. It includes 24 effects; the ATH-R50x is a passive wired listening device.
• Best for open-back reference listening → Audio-Technica ATH-R50x. Its open architecture and stated 5 Hz–40,000 Hz response are designed for natural, detailed listening.
• Best for a lighter headphone fit → Audio-Technica ATH-R50x. Its stated weight is 207 g, with a padded headband and breathable velour earpads.
• Best for flexible headphone cable lengths → Audio-Technica ATH-R50x. The included detachable cables are 3.0 m and 1.2 m, with 3.5 mm plugs and 1/4-inch adapters.
• Best when you need a bundled mixer-and-headphone setup → Mackie ProFX16v3. Its bundle includes closed-back Tascam headphones and a hard case, while the ATH-R50x listing describes the headphones themselves.
• Best for a quiet, noise-isolating work environment → Neither is a guaranteed fit from these specs. The Audio-Technica is open-back with no noise control, and the Mackie is a mixer rather than a noise-isolating headset.
The long-tail searches around foldable wireless earbuds for remote work, a volume limiting kids headset for remote work, or fast charging on-ear headphones for remote work describe categories these two products do not match. Neither product is described as wireless or foldable, and the provided specifications do not identify volume limiting or fast charging. If those are your must-haves, neither is the right match based on the available product details.
In my opinion, I’d choose the Mackie ProFX16v3 for a remote-work setup that also needs multichannel audio management, effects, and USB recording. It does far more than headphone monitoring, which is exactly the point if your work involves recording or combining sources.
I’d choose the Audio-Technica ATH-R50x instead if I already had an audio source and wanted wired open-back headphones for extended, detailed listening. The right pick comes down to whether you need to manage audio or hear it.
No. It is a 16-channel, 4-bus effects mixer with USB connectivity. This bundle also includes closed-back Tascam TH-02 headphones, but those do not turn the mixer into a headset.
No. They are wired headphones with a 3.5 mm connection. The package includes two detachable cables, one 3.0 m and one 1.2 m, along with 1/4-inch adapters.
They can suit desk work where natural, detailed listening is the priority and room noise is manageable. Their open-back design and lack of noise control make them less suited to blocking surrounding sound or keeping headphone audio contained.
Choose the Mackie if you need to mix sources and record through USB; it supports 2x4 USB I/O and 24-bit/192 kHz recording. Choose the ATH-R50x if you need headphones to listen through a compatible device, rather than a mixer.
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