Publication
2016-
Sung WJ, Kim D, Zhu A, Cho N, Yoo HM, Noh JH, Kim KM, Lee HS, Hong J. The lysosome as a novel therapeutic target of EGFR-mediated tumor inflammation. Front Pharmacol. 2022 Nov 11;13:1050758.
Yao Y, Ren Z, Yang R, Mei Y, Dai Y, Cheng Q, Xu C, Xu X, Wang S, Kim KM, Noh JH, Zhu J, Zhao N, Liu YU, Mao G, Sima J. Salidroside reduces neuropathology in Alzheimer's disease models by targeting NRF2/SIRT3 pathway. Cell Biosci. 2022 Nov 4;12(1):180.
Lodde V, Floris M, Munk R, Martindale JL, Piredda D, Napodano CMP, Cucca F, Uzzau S, Abdelmohsen K, Gorospe M, Noh JH, Idda ML. Systematic identification of NF90 target RNAs by iCLIP analysis. Sci Rep. 2022 Jan 10;12(1):364.
Driscoll RK, Krasniewski LK, Cockey SG, Yang JH, Piao Y, Lehrmann E, Zhang Y, Michel M, Noh JH, Cui CY, Gorospe M. GRSF1 deficiency in skeletal muscle reduces endurance in aged mice, AGING. 2021 Jun; 13(11): 14557-14570.
Kim KM, Meng Q, Perez de Acha O, Mustapic M, Cheng A, Eren E, Kundu G, Piao Y, Munk R, Wood WH 3rd, De S, Noh JH, Delannoy M, Cheng L, Abdelmohsen K, Kapogiannis D, Gorospe M. Mitochondrial RNA in Alzheimer's Disease Circulating Extracellular Vesicles, Front Cell Dev Biol. 2020 Nov; 8: 581882.
Pandey PR, Yang JH, Tsitsipatis D, Panda AC, Noh JH, Kim KM, Munk R, Nicholson T, Hanniford D, Argibay D, Yang X, Martindale JL, Chang MW, Jones SW, Hernando E, Sen P, De S, Abdelmohsen K, Gorospe M. circSamd4 represses myogenic transcriptional activity of PUR proteins, Nucleic Acids Res. 2020 Apr; 48(7): 3789-3805.
Noh JH, Kim KM, Pandey PR, Hooten NN, Munk R, Kundu G, De S, Martindale JL, Yang X, Evans MK, Abdelmohsen K, Gorospe M*. Loss of RNA-binding proteins GRSF1 activates mTOR to elicit a proinflammatory transcriptional program, Nucleic Acids Res. 2019 Mar; 47(5): 2472-2486.
Noh JH, Gorospe M. AKTions by Cytoplasmic lncRNA CASC9 Promote Hepatocellular Carcinoma Survival, Hepatology. 2018 Nov; 68(5): 1675-1677.
Noh JH, Kim KM, Idda ML, Martindale JL, Yang X, Abdelmohsen K, and Gorospe M*. GRSF1 suppresses cell senescence, AGING. 2018 Aug; 10(8): 1856-1866.
Kim KM, Noh JH, Bodogai M, Martindale JL, Pandey PR, Yang X, Biragyn A, Abdelmohsen K, and Gorospe M. SCAMP4 enhances the senescent cell secretome, Genes Dev. 2018 Jul; 32(13-14): 909-914.
Noh JH, Kim KM, McClusky WG, Abdelmohsen K, Gorospe M. Cytoplasmic functions of long noncoding RNAs, Wiley Interdiscip Rev RNA. 2018 May; 9(3): e1471.
Cui CY, Noh JH, Michel M, Gorospe M, Schlessinger D. STIM1, but not STIM2, Is the Calcium Sensor Critical for Sweat Secretion, J Invest Dermatol. 2018 Mar; 138(3): 704-707.
Kim KM, Noh JH, Bodogai M, Martindale JL, Yang X, Indig FE, Basu SK, Ohnuma K, Morimoto C, Johnson PF, Biragyn A, Abdelmohsen K, and Gorospe M. Identification of senescent-cell surface targetable protein DPP4, Genes Dev. 2017 Aug; 31(15): 1529-1534.
Kim J, Noh JH, Lee SK, Munk R, Sharov A, Lehrmann E, Zhang Y, Wang W, Abdelmohsen K, Gorospe M. LncRNA OIP5-AS1/cyrano suppresses GAK expression to control mitosis, Oncotarget. 2017 Jul; 8(30): 49409-49420.
Kim KM, Noh JH, Abdelmohsen K, Gorospe M. Mitochondrial noncoding RNA transport, BMB Rep. 2017 Apr; 50(4): 164-174.
Abdelmohsen K, Panda AC, Munk R, Grammatikakis I, Dudekula DB, De S, Kim J, Noh JH, Kim KM, Martindale JL, Gorospe M. Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1, RNA Biol. 2017 Mar; 14(3): 361-369.
Cascajo MV, Abdelmohsen K, Noh JH, Fernández-Ayala DJ, Willers IM, Brea G, López-Lluch G, Valenzuela-Villatoro M, Cuezva JM, Gorospe M, Siendones E, Navas P. RNA-binding proteins regulate cell respiration and coenzyme Q biosynthesis by post-transcriptional regulation of COQ7, RNA Biol. 2016 Jul; 13(7): 622-34.
Noh JH, Kim KM, Abdelmohsen K, Yoon JH, Panda AC, Munk R, Curtis J, Moad CA, Indig FE, de Paula W, Dudekula DB, De S, Yang X, Martindale JL, de Cabo R, and Gorospe M. HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRP, Genes Dev. 2016 May; 30(10): 1224-39.
Kim J, Abdelmohsen K, Yang X, De S, Grammatikakis I, Noh JH, Gorospe M. LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR, Nucleic Acids Res. 2016 Mar; 44(5): 2378-92.
Panda AC, Abdelmohsen K, Martindale JL, Di Germanio C, Yang X, Grammatikakis I, Noh JH, Zhang Y, Lehrmann E, Dudekula DB, De S, Becker KG, White EJ, Wilson GM, de Cabo R, Gorospe M. Novel RNA-binding activity of MYF5 enhances Ccnd1/Cyclin D1 mRNA translation during myogenesis, Nucleic Acids Res. 2016 Mar; 44(5): 2393-408.
Kim J, Kim KM, Noh JH, Yoon JH, Abdelmohsen K, Gorospe M. Long noncoding RNAs in diseases of aging, Biochim Biophys Acta. 2016 Jan; 1859(1): 209-21.
2004-2015 click ->
Park HJ, Noh JH, Eun JW, Koh YS, Seo SM, Park WS, Lee JY, Chang K, Seung KB, Kim PJ, Nam SW. Assessment and diagnostic relevance of novel serum biomarkers for early decision of ST-elevation myocardial infarction. Oncotarget. 2015;6(15):12970-83.
Cascajo MV, Abdelmohsen K, Noh JH, Fernández-Ayala DJ, Willers IM, Brea G, López-Lluch G, Valenzuela-Villatoro M, Cuezva JM, Gorospe M, Siendones E, Navas P. RNA-binding proteins regulate cell respiration and coenzyme Q biosynthesis by post-transcriptional regulation of COQ7. RNA Biol. 2015.
Abdelmohsen K, Panda AC, De S, Grammatikakis I, Kim J, Ding J, Noh JH, Kim KM, Mattison JA, de Cabo R, Gorospe M. Circular RNAs in monkey muscle: age-dependent changes. Aging(Albany NY). 2015;7(11):903-10.
Je-Hyun Yoon, Supriyo De, Subramanya Srikantan, Kotb Abdelmohsen, Ioannis Grammatikakis, Jiyoung Kim, Kyoung Mi Kim, Ji Heon Noh, Elizabeth J.F. White, Jennifer L. Martindale, Xiaoling Yang, Min-Ju Kang, William H. Wood 3rd, Nicole Noren Hooten, Michele K. Evans, Kevin G. Becker, Vidisha Tripathi, Kannanganattu V. Prasanth, Gerald M. Wilson, Thomas Tuschl, Nicholas T. Ingolia, Markus Hafner, Myriam Gorospe. PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity. Nat Commun. 2014;5:5248.
Noh JH, Bae HJ, Eun JW, Shen Q, Park SJ, Kim HS, Nam B, Shin WC, Lee EK, Lee K, Jang JJ, Park WS, Lee JY, Nam SW. HDAC2 Provides a Critical Support to Malignant Progression of Hepatocellular Carcinoma through Feedback Control of mTORC1 and AKT. Cancer Res. 2014;74(6):1728-38.
Abdelmohsen K, Panda AC, Kang MJ, Guo R, Kim J, Grammatikakis I, Yoon JH, Dudekula DB, Noh JH, Yang X, Martindale JL,Gorospe M. 7SL RNA represses p53 translation by competing with HuR. Nucleic Acids Res. 2014;42(15):10099-111.
Kang MJ, Abdelmohsen K, Hutchison ER, Mitchell SJ, Grammatikakis I, Guo R, Noh JH, Martindale JL, Yang X, Lee EK, Faghihi MA, Wahlestedt C, Troncoso JC, Pletnikova O, Perrone-Bizzozero N, Resnick SM, de Cabo R, Mattson MP, Gorospe M. HuD regulates coding and noncoding RNA to induce APP→Aβprocessing. Cell Rep. 2014;7(5):1401-9.
Bae HJ, Noh JH, Kim JK, Eun JW, Jung KH, Kim MG, Chang YG, Shen Q, Kim SJ, Park WS, Lee JY, Nam SW. MicroRNA-29c functions as a tumor suppressor by direct targeting oncogenic SIRT1 in hepatocellular carcinoma. Oncogene. 2014;33(20):2557-67.
Noh JH, Chang YG, Kim MG, Jung KH, Kim JK, Bae HJ, Eun JW, Shen Q, Kim SJ, Kwon SH, Park WS, Lee JY, Nam SW. MiR-145 functions as a tumor suppressor by directly targeting histone deacetylase 2 in liver cancer. Cancer Lett. 2013;335(2):455-62.
Kim JK, Noh JH, Eun JW, Jung KH, Bae HJ, Shen Q, Kim MG, Chang YG, Kim SJ, Park WS, Lee JY, Borlak J, Nam SW. Targeted inactivation of HDAC2 restores p16INK4a activity and exerts antitumor effects onhuman gastric cancer. Mol Cancer Res2013;11(1):62-73.
Kim JK, Noh JH, Jung KH, Eun JW, Bae HJ, Kim MG, Chang YG, Shen Q, Park WS, Lee JY, Borlak J, Nam SW. Sirtuin7 oncogenic potential in human hepatocellular carcinoma and its regulation by the tumor suppressors MiR-125a-5p and MiR-125b. Hepatology2013;57(3):1055-67.
Jung KH, Kim JK, Noh JH, Eun JW, Bae HJ, Kim MG, Chang YG, Shen Q, Kim SJ, Kwon SH, Park WS, Lee JY, Nam SW. Characteristic molecular signature for the early detection and prediction of polycyclic aromatic hydrocarbons in rat liver. Toxicol Lett2013;216(1):1-8.
Bae HJ, Chang YG, Noh JH, Kim JK, Eun JW, Jung KH,Kim MG, Shen Q, Ahn YM, Kwon SH, ParkWS, Lee JY, Nam SW. DBC1 does not function as a negative regulator of SIRT1 in liver cancer. Oncol Lett2012;4(5):873-877.
Jung KH, Kim JK, Kim MG, Noh JH, Eun JW, Bae HJ, Chang YG, Shen Q, Park WS, Lee JY, Nam SW. Characteristic molecular signature for early detection and prediction of persistent organicpollutants in rat liver. Environ Sci Technol2012;46(23):12882-9.
Xie HJ#, Noh JH#, Kim JK, Jung KH, Eun JW, Bae HJ, Kim MG, Chang YG, Lee JY, Park H , Nam SW. HDAC1 Inactivation Induces Mitotic Defect and Caspase-independent Autophagic Cell Death in Liver Cancer. PLoS One2012;7(4):e34265. #equalcontributions.
Jung KH, Noh JH, Kim JK, Eun JW, Bae HJ, Xie HJ, Chang YG, Kim MG, Park H, Lee JY, Nam SW. HDAC2 overexpression confers oncogenic potential to human lung cancer cells by deregulating expression of apoptosis and cell cycle proteins. J Cell Biochem2012;113(6):2167-77.
Jung KH, Noh JH, Kim JK, Eun JW, Bae HJ, Chang YG, Kim MG, Park WS, Lee JY, Lee SY, Chu IS, Nam SW. HDAC6 functions as a tumor suppressor by activating JNK-mediated beclin 1-dependentautophagic cell death in liver cancer. Hepatology2012;56(2):644-57.
Noh JH, Jung KH, Kim JK, Eun JW, Bae HJ, Xie HJ, Chang YG, Kim MG, Park WS,Lee JY, Nam SW. Aberrant Regulation of HDAC2 Mediates Proliferation of Hepatocellular Carcinoma Cellsby Deregulating Expression of G1/S Cell Cycle Proteins. Plos One2011;6(11):e28103.
Jung KH, Noh JH, Eun JW, Kim JK, Bae HJ, Xie H, Jang JJ, Ryu JC, ParkWS, Lee JY, Nam SW. Molecular signature for early detection and prediction of polycyclic aromatic hydrocarbons in peripheral blood. Environ Sci Technol2011;45(1):300-6.
Kim JK, Jung KH, Noh JH, Eun JW, Bae HJ, Xie HJ, Jang JJ, Ryu JC, Park WS, Lee JY, Nam SW.Identification of characteristic molecular signature for volatile organic compounds inperipheral blood of rat. Toxicol Appl Pharmacol2011;250(2):162-9.
Kim JK, Kim PJ, Jung KH, Noh JH, Eun JW, Bae HJ, Xie HJ, Shan JM, Ping WY, Park WS, Lee JY, Nam SW. Decreased expression of annexin A10 in gastric cancer and its overexpression in tumor cellgrowth suppression. Oncol Rep2010;24(3):607-12.
Jung KH, Kim JK, Noh JH, Eun JW, Bae HJ, Xie HJ, Ahn YM, Park WS, Lee JY, Nam SW. Targeted disruption of Nemo-like kinase inhibits tumor cell growth by simultaneoussuppression of cyclin D1 and CDK2 in human hepatocellular carcinoma. J Cell Biochem2010;110(3):687-96.
Eun JW, Kwack SJ, Noh JH, Jung KH, Kim JK, Bae HJ, Xie H, Ryu JC, Ahn YM, Park WS, Lee JY, Rhee GS,Nam SW. Identification of post-generation effect of 3,4-methylenedioxymethamphetamine on themouse brain by large-scale gene expression analysis. Toxicology Letters2010;195:60–67.
Kim JK, Jung KH, Noh JH, Eun JW, Bae HJ, Xie HJ, Ahn YM, Ryu JC, Park WS, Lee JY, Nam SW. Targeted disruption of S100P suppresses tumor cell growth by down-regulation of cyclin D1and CDK2 in human hepatocellular carcinoma. Int J Oncol2009;35(6):1257-64.
Bae HJ, Noh JH, Eun JW, Kim JK, Jung KH, Xie HJ, Ahn YM, Ryu JC, Park WS, Lee JY, Nam SW. Decreased Expression of the Suppressor of Cytokine Signaling 6 in Human HepatocellularCarcinoma. Mol Cell Toxicology2009;5(3):193-197.
Bae HJ, Eun JW, Noh JH, Kim JK, Jung KH, Xie HJ, Park WS, Lee JY, Nam SW. Down-regulation of transforming growth factor beta receptor type III in hepatocellularcarcinoma is not directly associated with genetic alterations or loss of heterozygosity. Oncol Rep2009;22(3):475-80.
Noh JH, Song JH, Eun JW, Kim JK, Jung KH, Bae HJ, Xie HJ, Ryu JC, Ahn YM, Wee SJ, Park WS, Lee JY, Nam SW. Systemic cell-cycle suppression by Apicidin, a histone deacetylase inhibitor, in MDA-MB-435 cells. Int J Mol Med2009;24(2):205-26.
Bae HJ, Song JH, Noh JH, Kim JK, Jung KH, Eun JW, Xie HJ, Ryu JC, Ahn YM, Kim SY, Lee SH,Yoo NJ, Lee JY, Park WS, Nam SW. Low frequency mutation of the Ephrin receptor A3 gene in hepatocellular carcinoma. Neoplasma2009;56(4):331-4.
Eun JW, Kwack SJ,Noh JH, Jung KH, Kim JK, Bae HJ, Xie H, Ryu JC, Ahn YM, Min JH, Park WS, Lee JY, Rhee GS, Nam SW. Transcriptomic configuration of mouse brain induced by adolescent exposure to 3,4-methylenedioxymethamphetamine. Toxicology andApplied Pharmacology2009; 237: 91–101.
Xie HJ, Bae HJ, Noh JH, Eun JW, Kim JK, Jung KH, Ryu JC, Ahn YM, Kim SY, Lee SH, Yoo NJ, Lee JY, Park WS, Nam SW. Mutational analysis of JAK1 gene in human hepatocellular carcinoma. Neoplasma2009;56(2):136-40.
Eun JW, Ryu SY, Noh JH, Lee MJ, Jang JJ, Ryu JC, Jung KH, Kim JK, Bae HJ, Xie H, Kim SY, Lee SH, Park WS, Yoo NJ, Lee JY, Nam SW. Discriminating the molecular basis of hepatotoxicity using the large-scale characteristicmolecular signatures of toxicants by expression profiling analysis. Toxicology2008;249(2-3):176-83.
Xie HJ, Eun JW, Noh JH, Jeong KH, Kim JK, Kim SY, Lee SH, Park WS, Yoo NJ, Lee JY, Nam SW. Molecular Classification and Characterization of Human Gastric Adenocarcinoma throughDNA Microarray. Mol Cell Toxicology2007;3(3):190-194.
Noh JH, Eun JW, Ryu SY, Jeong KW, Kim JK, Lee SH, Park WS, Yoo NJ, Lee JY, Nam SW. Increased expression of histone deacetylase 2 is found in human hepatocellular carcinoma.Mol Cell Toxicology2006; 2(3): 166-169.
Noh JH, Ryu SY, Eun JW, Song J, Ahn YM, Kim SY, Lee SH, Park WS, Yoo NJ, Lee JY, Lee SN, Nam SW. Identification of large-scalemolecular changes 1 of Autotaxin(ENPP2) knock-down by smallinterfering RNA in breast cancer cells. Mol Cell Biochem2006;288(1-2):91-106.
Nam SW, Lee JH, Noh JH, Lee SN, Kim SY, Lee SH, Park CK, Ahn YM, Park WS, Yoo NJ, Lee JY. Comparative analysis of expression profiling of early-stage carcinogenesis using nodule-innodule-type hepatocellular carcinoma. Eur J Gastroenterol Hepatol2006;18(3):239-247.
Song J, Clair T, Noh JH, Eun JW, Ryu SY, Lee SN, Ahn YM, Kim SY, Lee SH, Park WS, Yoo NJ, Lee JY, Nam SW.Autotaxin (lysoPLD/NPP2) protects fibroblasts from apoptosis through its enzymatic product, lysophosphatidic acid, utilizing albumin-bound substrate. BiochemBiophys Res Commun. 2005;337(3):967-75.
Song J, Noh JH, Lee JH, Eun JW, Ahn YM, Kim SY, Lee SH, Park WS, Yoo NJ, Lee JY, Nam SW. Increased expression of histone deacetylase 2 is found in human gastric cancer. APMIS. 2005;113(4):264-8.
Park JY, Kim SY, Lee JH, Song J, Noh JH, Lee SH, Park WS, Yoo NJ, Lee JY, Nam SW. Application of amplified RNA and evaluation of cRNA targets for spotted-oligonucleotidemicroarray. BiochemBiophys Res Commun. 2004;325(4):1346-52.