Developmental Genetics Lab

"Welcome to Developmental Genetics Lab"





















“Generation and Phentyping of Genetically modified mice”

Developmental Genetics Lab aims to understand the developmental process of mammals and to identify therapeutic targets for genetic diseases. We focus on genes associated with vascular development, and muscle regeneration, and intestinal homeostasis. To study the function of these genes we generate and analyze their knockout mice. In addition, we perform many research projects using knockout mice in collaboration with other researchers.




Gallery

Generation of Knockout mice

Chimera (black and brown) and knockout mice (brown)

Spr-knockout mice

Growth retardation of Spr-knockout mice (left) and his wild type littermate (right)

Tmem100-knockout mice (angiogenesis)

Abnormal development of retinal vasculature in Tmem100-knockout mice

Tmem100-knockout mice (lymphagiogenesis)

Abnormal connection between the cardinal veins and lymphatic vessels in Tmem100-knockout mice.