2024
1. Nien-Tzu Yeh, Tzu-Chen Lin, I-Ju Liu, Shang-Hsiu Hu, Tsai-Ching Hsu, Hao-Yang Chin, Bor-Show Tzang* and Wen-Hsuan Chiang*, Hyaluronic acid-covered ferric Ion-rich nanobullets with high zoledronic acid payload for breast tumor-targeted chemo/chemodynamic therapy, Int. J. Biol. Macromol. 2024, 279, 135271. (Corresponding author, SCI, IF: 7.7, Polymer Science: 6/95)
2. Kai-An Liang, Hsiang-Yun Chih, I-Ju Liu, Nien-Tzu Yeh, Tsai-Ching Hsu, Hao-Yang Chin, Bor-Show Tzang* and Wen-Hsuan Chiang*, Tumor-targeted delivery of hyaluronic acid/polydopamine-coated Fe2+-doped nano-scaled metal-organic frameworks with doxorubicin payload for glutathione depletion-amplified chemodynamic-chemo cancer therapy, J. Colloid Interface Sci. 2025, 677, 400-415. (Corresponding author, SCI, IF: 9.4, CHEMISTRY, PHYSICAL: 32/178)
3. Yu-Hsin Chen, I-Ju Liu, Tzu-Chen Lin, Min-Chen Tsai, Shang-Hsiu Hu, Tsai-Ching Hsu, Yi-Ting Wu, Bor-Show Tzang* and Wen-Hsuan Chiang*, PEGylated chitosan-coated nanophotosensitizers for effective cancer treatment by photothermal-photodynamic therapy combined with glutathione depletion, Int. J. Biol. Macromol. 2024, 266, 131359. (Corresponding author, SCI, IF: 7.7, Polymer Science: 6/95)
4. Yu-Ling Liu, Tzu-Hao Wang, Nien-Tzu Yeh, Bor-Show Tzang, I-Ting Wu, Hao-Yang Chin, Shang-Hsiu Hu, Tsai-Ching Hsu* and Wen-Hsuan Chiang*, Tumor-activated targetable photothermal-chemotherapy of
IR780/zoledronic acid-containing hybrid polymeric nanoassemblies with folate modification to treat aggressive breast cancer, Nanoscale 2024, 16, 1415–1427. (Corresponding author, SCI, IF: 5.8, PHYSICS, APPLIED: 33/179)
5. Bhanu Nirosha Yalamandala, Yu-Jen Chen, Ya-Hui Lin, Thi My Hue Huynh, Wen-Hsuan Chiang, Tsu-Chin Chou, Heng-Wei Liu, Chieh-Cheng Huang, Yu-Jen Lu, Chi-Shiun Chiang, Li-An Chu, and Shang-Hsiu Hu*, A Self-Cascade Penetrating Brain Tumor Immunotherapy Mediated by Near-Infrared II Cell Membrane-Disrupting Nanoflakes via Detained Dendritic Cells, ACS Nano 2024, 18, 18712–18728 (SCI, IF: 15.8, CHEMISTRY, MULTIDISCIPLINARY: 14/230)
6. Thi My Hue Huynh, Van-Sieu Luc, Min-Ren Chiang, Wei-Han Weng, Chien-Wen Chang, Wen-Hsuan Chiang, Yu-Chen Liu, Chun-Yu Chuang, Chia-Chih Chang,*and Shang-Hsiu Hu*, Programmed Lung Metastasis Immunotherapy via Cascade-Responsive Cell Membrane-Mimetic Copolymer-Wrapped Nanoraspberry-Mediated Elesclomol-Copper Delivery, Adv. Funct. Mater. 2024, 2401806. (SCI, IF: 18.5, Materials Science, Multidisciplinary: 21/438)
7. Ting-Hsien Wu, Yu-Jen Lu, Min-Ren Chiang, Ping-Hua Chen, Yu-Sheng Lee, Ming-Yin Shen, Wen-Hsuan Chiang, Yu-Chen Liu, Chun-Yu Chuang, Hsiao-Chun Amy Lin, Shang-Hsiu Hu*, Lung metastasis-Harnessed in-Situ adherent porous organic nanosponge-mediated antigen capture for A self-cascaded detained dendritic cells and T cell infiltration, Biomaterials 2024, 305, 122443. (SCI, IF: 12.8, ENGINEERING, BIOMEDICAL: 4/122)
2023
8. Tzu-Hao Wang, Ming-Yen Shen, Nien-Tzu Yeh, Yu-Hsin Chen, Tsai-Ching Hsu, Hao-Yang Chin, Yi-Ting Wu, Bor-Show Tzang* and Wen-Hsuan Chiang*, Photothermal nanozymes to self-augment combination cancer therapy by dual-glutathione depletion and hyperthermia/acidity-activated hydroxyl radical generation, J. Colloid Interface Sci. 2023, 650, 1698-1714. (Corresponding author, SCI, IF: 9.4, CHEMISTRY, PHYSICAL: 32/178)
9. Shih-Yu Huang, Nien-Tzu Yeh, Tzu-Hao Wang, Tsai-Ching Hsu, Hao-Yang Chin, Bor-Show Tzang* and Wen-Hsuan Chiang*, Onion-like doxorubicin-carrying polymeric nanomicelles with tumor acidity-sensitive dePEGylation to expose positively-charged chitosan shell for enhanced cancer chemotherapy, Int. J. Biol. Macromol. 2023, 227, 925-937. (Corresponding author, SCI, IF: 7.7, Polymer Science: 6/94)
10. Hsuan-Jung Huang, Shih-Yu Huang, Tzu-Hao Wang, Tzu-Yun Lin, Nan-Ching Huang, Orion Shih, U-Ser Jeng, Che-Yi Chu* and Wen-Hsuan Chiang*, Clay nanosheets simultaneously intercalated and stabilized by PEGylated chitosan as drug delivery vehicles for cancer chemotherapy, Carbohydr. Polym. 2023, 302, 120390. (Corresponding author, SCI, IF: 10.7, CHEMISTRY, ORGANIC: 1/58)
11. Ming-Yen Shen, Yu-Hsin Chen, Nien-Tzu Yeh, Tzu-Hao Wang and Wen-Hsuan Chiang*, Acidity/hydrogen peroxide-responsive PEGylated chitosan-modified polydopamine nanoparticles to realize effective photothermal conversion and intracellular drug delivery, Eur. Polym. J. 2023, 197, 112365. (Corresponding author, SCI, IF: 5.8, Polymer Science: 9/94)
12. Thi My Hue Huynh, Bhanu Nirosha Yalamandala, Min-Ren Chiang, Wei-Han Weng, Chien-Wen Chang, Wen-Hsuan Chiang, Lun-De Liao, Yu-Chen Liu, Shang-Hsiu Hu*, Programmed antigen capture-harnessed dendritic cells by margination-hitchhiking lung delivery, Journal of Controlled Release 2023, 358, 718-728. (SCI, IF: 10.5, Pharmacology and Pharmacy: 12/354)
13. Min-Ren Chiang, Wei-Ting Shen, Pin-Xuan Huang, Kang-Li Wang, Wei-Han Weng, Chien-Wen Chang, Wen-Hsuan Chiang, Yu-Chen Liu, Shing-Jyh Chang, Shang-Hsiu Hu*, Programmed T cells infiltration into lung metastases with harnessing dendritic cells in cancer immunotherapies by catalytic antigen-capture sponges, Journal of Controlled Release 2023, 360, 260–273. (SCI, IF: 10.5, Pharmacology and Pharmacy: 12/354)
14. Bhanu Nirosha Yalamandala, Thi My Hue Huynh, Min‐Ren Chiang, Wei‐Han Weng, Chien‐Wen Chang, Wen‐Hsuan Chiang and Shang‐Hsiu Hu*, Programmed Catalytic Therapy and Antigen Capture‐Mediated Dendritic Cells Harnessing Cancer Immunotherapies by In Situ‐Forming Adhesive Nanoreservoirs, Adv. Funct. Mater. 2023, 33, 2210644. (SCI, IF: 18.5, Materials Science, Multidisciplinary: 21/438)
2022
15. Ming-Hung Hsieh, Tzu-Hao Wang, Shang-Hsiu Hu, Tsai-Ching Hsu, Jia-Le Yow, Bor-Show Tzang* and Wen-Hsuan Chiang*, Tumor site-specific PEG detachment and active tumor homing of therapeutic PEGylated chitosan/folate-decorated polydopamine nanoparticles to augment antitumor efficacy of photothermal/chemo combination therapy, Chem. Eng. J. 2022, 446, 137243. (Corresponding author, SCI, IF: 13.3, ENGINEERING, CHEMICAL: 7/170)
16. Ya-Hsuan Chou, Yu-Ling Liu, Tsai-Ching Hsu, Jia Le Yow, Bor-Show Tzang* and Wen-Hsuan Chiang*, Tumor acidity-responsive polymeric nanoparticles to promote intracellular delivery of zoledronic acid by PEG detachment and positive charge exposure for enhanced antitumor potency, J. Mater. Chem. B 2022, 10, 4363-4374. (Corresponding author, SCI, IF: 6.1, Materials science, Biomaterials: 11/53) (Journal Cover)
17. Sheng-Jyun Huang, Tzu-Hao Wang, Ya-Hsuan Chou, Hui-Min David Wang, Tsai-Ching Hsu, Jia-Le Yow, Bor-Show Tzang* and Wen-Hsuan Chiang*, Hybrid PEGylated chitosan/PLGA nanoparticles designed as pH-responsive vehicles to promote intracellular drug delivery and cancer chemotherapy, Int. J. Biol. Macromol. 2022, 210, 565-578. (Corresponding author, SCI, IF: 7.7, Polymer Science: 6/94)
18. Jin-Wun Jhang, Ya-Hsuan Chou, Tzu-Hao Wang, Ming-Hung Hsieh and Wen-Hsuan Chiang*, One-pot green reduction and surface decoration of graphene oxide nanosheets with PEGylated chitosan for application in cancer photothermal therapy, J. Taiwan Inst. Chem. Eng. 2022, 134, 104359. (Corresponding author, SCI, IF: 5.5, ENGINEERING, CHEMICAL: 31/170)
19. Yu-Ning Hung, Yu-Ling Liu, Ya-Hsuan Chou, Shang-Hsiu Hu, Bill Cheng, Wen-Hsuan Chiang*, Promoted cellular uptake and intracellular cargo release of ICG/DOX-carrying hybrid polymeric nanoassemblies upon acidity-activated PEG detachment to enhance cancer photothermal/chemo combination therapy, Eur. Polym. J. 2022, 163, 110944. (Corresponding author, SCI, IF: 5.8, Polymer Science: 9/94)
20. Bhanu Nirosha Yalamandala, Pin-Hua Chen, Thrinayan Moorthy, Thi My Hue Huynh, Wen-Hsuan Chiang, Shang-Hsiu Hu*, Programmed Catalytic Therapy-Mediated ROS Generation and T-cell Infiltration in Lung Metastasis by Dual Metal Organic Framework (MOF) Nanoagnets, pharmaceutics 2022, 14, 527. (SCI, IF: 4.9, PHARMACOLOGY & PHARMACY: 45/354)
2021
21. Chih-Wei Ting, Ya-Hsuan Chou, Shih-Yu Huang, Wen-Hsuan Chiang*, Indocyanine green-carrying polymeric nanoparticles with acid-triggered detachable PEG coating and drug release for boosting cancer photothermal therapy, Colloids and Surfaces B: Biointerfaces. 2021, 208, 112048. (Corresponding author, SCI, IF: 5.4, BIOPHYSICS: 8/77)
22. Bhanu Nirosha Yalamandala, Wei-Ting Shen, Sheng-Hao Min, Wen-Hsuan Chiang, Shing-Jyh Chang, Shang-Hsiu Hu*, Advances in Functional Metal-Organic Frameworks-Based On-Demand Drug Delivery Systems for Tumor Therapeutics. Advanced NanoBiomed Research 2021, 1, 2100014. (SCI, IF: 4.0, ENGINEERING, BIOMEDICAL: 41/122)
2020
23. Min-Cong Xiao, Ya-Hsuan Chou, Yu-Ning Hung, Shang-Hsiu Hu, Wen-Hsuan Chiang*, Hybrid polymeric nanoparticles with high zoledronic acid payload and proton sponge-triggered rapid drug release for anticancer applications, Mater. Sci. Eng. C 2020, 116, 111277. (Corresponding author, SCI, IF: 8.1, Materials science, Biomaterials: 8/53)
24. Ching-Wei Hsu, Ming-Hung Hsieh, Min-Cong Xiao, Ya-Hsuan Chou, Tzu-Hao Wang and Wen-Hsuan Chiang*, pH-responsive polymeric micelles self-assembled from benzoic-imine-containing alkyl-modified PEGylated chitosan for delivery of amphiphilic drugs, Int. J. Biol. Macromol. 2020, 163, 1106-1116. (Corresponding author, SCI, IF: 7.7, Polymer Science: 6/94)
25. Shu-Chiao Liao, Chih-Wei Ting, Wen-Hsuan Chiang*, Functionalized polymeric nanogels with pH-sensitive benzoic-imine cross-linkages designed as vehicles for indocyanine green delivery, J. Colloid Interface Sci. 2020, 561, 11-22. (Corresponding author, SCI, IF: 9.4, CHEMISTRY, PHYSICAL: 32/178)
26. Reesha Kv, Te-I Liu, I.-Lin Lu, Chia-Chen Liu, Hsin-Hung Chen, Ting-Yu Lu, Wen-Hsuan Chiang*, Hsin-Cheng Chiu*, Tumor microenvironment-responsive and oxygen self-sufficient oil droplet nanoparticles for enhanced photothermal/photodynamic combination therapy against hypoxic tumors, Journal of Controlled Release 2020, 328, 87-99. (Corresponding author, SCI, IF: 10.5, Pharmacology and Pharmacy: 12/354)
27. Shih-Hong Chen, Te-I Liu, Cheng-Lin Chuang, Hsin-Hung Chen, Wen-Hsuan Chiang*, Hsin-Cheng Chiu*, Alendronate/folic acid-decorated polymeric nanoparticles for hierarchically targetable chemotherapy against bone metastatic breast cancer, J. Mater. Chem. B 2020, 8, 3789-3800. (Journal Cover) (Corresponding author, SCI, IF: 6.1, Materials science, Biomaterials: 11/53)
28. I.-Lin Lu, Te-I Liu, Hsiao-Chieh Lin, Siou-Han Chang, Chun-Liang Lo, Wen-Hsuan Chiang*, Hsin-Cheng Chiu*, IR780-loaded zwitterionic polymeric nanoparticles with acidity-induced agglomeration for enhanced tumor retention, Eur. Polym. J. 2020, 122, 109400. (Corresponding author, SCI, IF: 5.8, Polymer Science: 9/94)
29. Ru-Siou Hsu, Jen-Hung Fang, Wei-Ting Shen, Yu-Chen Sheu, Cheng-Kuan Su, Wen-Hsuan Chiang, Shang-Hsiu Hu*, Injectable DNA-Architected Nanoraspberry Depot-Mediated On-Demand Programmable Refilling and Release Drug Delivery, Nanoscale 2020, 12, 11153–11164. (SCI, IF: 5.8, PHYSICS, APPLIED: 33/179).
30. Jen-Hung Fang, Che-Hau Liu, Ru-Siou Hsu, Yin-Yu Chen, Wen-Hsuan Chiang, Hui-Min David Wang, Shang-Hsiu Hu*, Transdermal composite microneedle composed of mesoporous iron oxide nanoraspberry and PVA for androgenetic alopecia treatment, Polymers 2020, 12, 1392. (SCI, IF: 4.7, Polymer Science: 18/94)