Published Research on Lipedema

Lipedema Research

Use to show Lipedema is a medical condition that inflicts pain, limits mobility, is progressive & can cause comorbidities that lead to disability and premature death

• An approach to lipedema: a literature review of current knowledge of an underestimated health problem

• Association between serum vitamin D and mood disorders in a cohort of lipedema patients

• Current Mechanistic Understandings of Lymphedema and Lipedema: Tales of Fluid, Fat, and Fibrosis

• Development of a questionnaire and screening model for lipedema

• Differential diagnoses and treatment of lipedema

• Dilated Blood and Lymphatic Microvessels, Angiogenesis, Increased Macrophages, and Adipocyte Hypertrophy in Lipedema Thigh Skin and Fat Tissue

• Distinct Cytokine Profile and Stromal Vascular Fraction Metabolic Status without Significant Changes in the Lipid Composition Characterizes Lipedema

• Evaluation and Management of the Fat Leg Syndrome

• Exploration of Patient Characteristics and Quality of Life in Patients with Lipoedema Using a Survey

• Functional and Therapeutic Indications of Liposuction Personal Experience and Review of the Literature

• Indications of Peripheral Pain, Dermal Hypersensitivity, and Neurogenic Inflammation in Patients with Lipedema

• Insights on the Pathophysiology, Diagnosis and Treatment of Lipedema

• Investigation of clinical characteristics and genome associations in the ‘UK Lipoedema’ cohort

• Key signaling networks are dysregulated in patients with the adipose tissue disorder, lipedema

• Lipedema: A Call to Action!

• Lipedema, a frequently unrecognized problem

• Lipedema, a Rare Disease

• Lipedema: A Relatively Common Disease with Extremely Common Misconceptions

• Lipedema: A Review of the Literature

• Lipedema: an inherited condition

• Lipedema: an overview of its clinical manifestations, diagnosis and treatment of the disproportional fatty deposition syndrome - systematic review

• Lipedema-An update

• Lipedema: Anatomical study, diagnosis, and perioperative setting

• Lipedema and the Potential Role of Estrogen in Excessive Adipose Tissue Accumulation

• Lipedema: diagnostic and management challenges

• Lipedema Fat and Signs and Symptoms of Illness, Increase with Advancing Stage

• Lipedema: friend and foe

• Lipoedema: from clinical presentation to therapy. A review of the literature

• Lipoedema is not lymphoedema: A review of current literature

• Lipedema: More than a “Fat Legs” Problem. Update on Physiopathology, Diagnosis and Surgical Treatment

• Lipedema: up-to-date of a long forgotten disease

• Lipedema with genital lymphatic vesicles

• Lymphatic function and anatomy in early stages of lipedema

• Multi-Gene Panel to Identify Lipedema-Predisposing Genetic Variants by a Next-Generation Sequencing Strategy

• New Insights on Lipedema: The Enigmatic Disease of the Peripheral Fat

• Pain with lipoedema: Attempt to approximate

• Platelet factor 4 is a biomarker for lymphatic-promoted disorders

• Prevalence of lipoedema in professional women in Germany

• Quality of life, its factors, and sociodemographic characteristics of Polish women with lipedema

• S1 guidelines: Lipedema

• Specialist approaches to managing lipoedema

• Standard of care for lipedema in the United States

• Subcutaneous Adipose Tissue Diseases: Dercum Disease, Lipedema, Familial Multiple Lipomatosis, and Madelung Disease

• Subcutaneous Adipose Tissue Edema in Lipedema Revealed by Noninvasive 3T MR Lymphangiography

• Tissue Sodium Content is Elevated in the Skin and Subcutaneous Adipose Tissue in Women with Lipedema

• Update in the management of lipedema

• Ultrasound criteria for lipedema diagnosis

• Upper and Lower Extremity Measurement of Tissue Sodium and Fat Content in Patients with Lipedema

• 3D Spheroids Derived from Human Lipedema ASCs Demonstrated Similar Adipogenic Differentiation Potential and ECM Remodeling to Non-Lipedema ASCs In Vitro

Liposuction for Lipedema Research

Use to show liposuction is safe, effective long-term, not experimental, proven & accepted by the worldwide medical community

• A 10-Year Retrospective before-and-after Study of Lipedema Surgery: Patient-Reported Lipedema-Associated Symptom Improvement after Multistage Liposuction

• Does tumescent liposuction damage the lymph vessels in lipoedema patients?

• Improvements in patients with lipedema 4, 8 and 12 years after liposuction

• Liposuction: A Surgical Tool to Improve the Quality of Life after Morbid Medical Conditions: Review of Literature

• Liposuction in the Treatment of Lipedema: A Longitudinal Study

• Liposuction is an effective treatment for lipedema – results of a study with 25 patients

• Liposuction of Lipedema to Prevent Later Joint Complications

• Liposuction treatment improves disease-specific quality of life in lipoedema patients

• Long-term benefit of liposuction in patients with lipoedema: a follow-up study after an average of 4 and 8 years

• Long-term Outcome After Surgical Treatment of Lipedema

• Metabolic Effects of Large-Volume Liposuction for Obese Healthy Women: A Meta-Analysis of Fasting Insulin Levels

• Survey Outcomes of Lipedema Reduction Surgery in the United States

• Treatment of lipedema by low-volume micro-cannular liposuction in tumescent anesthesia: Results in 111 patients

• Treatment of lipoedema using liposuction: Results of our own surveys

• Tumescent liposuction in lipoedema yields good long-term results

• Water Jet-Assisted Liposuction for Patients with Lipoedema: Histologic and Immunohistologic Analysis of the Aspirates of 30 Lipoedema Patients

Obesity Research

Use to show obesity is different from Lipedema

• Neck circumference can differentiate obese from non-obese individuals

• Performance of neck circumference to predict obesity and metabolic syndrome among adult Saudis: a cross-sectional study

• Rare adipose disorders (RADs) masquerading as obesity

• Relationship Between Second to Fourth Digit Ratios and Obesity, Muscle Mass

Conservatives Therapies Research

Use to show MLD may be helpful in reducing Lipolymphedema, or that MLD isn't a cure for Lipedema

• Effectiveness of manual lymphatic drainage and low level laser in the treatment of a client with lipedema: an N-of-1 trial

• Effects of Complete Decongestive Therapy or Intermittent Pneumatic Compression Therapy or Exercise Only in the Treatment of Severe Lipedema: A Randomized Controlled Trial

• Effects of Complex Decongestive Physiotherapy Applications on Lower Extremity Circumference and Volume in Patients with Lipedema

• Lipedema Can Be Treated Non-Surgically: A Report of 5 Cases

• Physical Therapy in Women with Early Stage Lipedema: Potential Impact of Multimodal Manual Therapy, Compression, Exercise, and Education Interventions

Lipolymphedema & Lymphedema Research

Use to show connection between Lymphedema & Lipedema, increased chance of Lipedema patients developing Lymphedema

• Exploring disease interrelationships in patients with lymphatic disorders: A single center retrospective experience

• Lymphedema diagnosis, treatment, and follow-up from the view point of physical medicine and rehabilitation specialists

Professional Medical Organizations That Recognize Lipedema

Use to show that Lipedema is a recognized condition treated by many different types of medical providers and specialists

• American College of Cardiology
  2021 ACC/AHA/SVM/ACP Advanced Training Statement on Vascular Medicine (Revision of the 2004 ACC/ACP/SCAI/SVMB/SVS Clinical Competence Statement on Vascular Medicine and Catheter-Based Peripheral Vascular Interventions)

• American Society of Plastic Surgeons
  Treating Lipedema With Liposuction May Help Women With 'Painful Fat' Disease

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