The Primera Divisin is currently second in the UEFA rankings of European leagues based on their performances in European competitions over a five-year period, behind England's Premier League, but ahead of Italy's Serie A and Germany's Bundesliga.

Function: Replaces a sequence of glyphs with a single glyph which is preferred for typographic purposes. This feature covers the ligatures which the designer/manufacturer judges should be used in normal conditions.


Liga Acb


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Recommended implementation: The 'liga' table maps sequences of glyphs to corresponding ligatures (GSUB lookup type 4). Ligatures with more components must be stored ahead of those with fewer components in order to be found. The set of standard ligatures will vary by design and script.

Function: Replaces default alphabetic glyphs with the corresponding ordinal forms for use after figures. One exception to the follows-a-figure rule is the numero character (U+2116), which is actually a ligature substitution, but is best accessed through this feature.

Transmission of leptospirosis occurs through contact of mucous membranes and abraded skin with freshwater contaminated by pathogenic Leptospira spp. Exposure to physiological osmolarity induces leptospires to express high levels of the Lig surface proteins containing imperfect immunoglobulin-like repeats that are shared or differ between LigA and LigB. We report that osmotic induction of Lig is accompanied by 1.6- to 2.5-fold increases in leptospiral adhesion to immobilized extracellular matrix and plasma proteins, including collagens I and IV, laminin, and especially fibronectin and fibrinogen. Recombinant LigA-unique and LigB-unique repeat proteins bind to these same host ligands. We found that the avidity of LigB in binding fibronectin is comparable to that of the Staphylococcus aureus FnBPA D repeats. Both LigA- and LigB-unique repeats interact with the amino-terminal fibrin- and gelatin-binding domains of fibronectin, which are also recognized by fibronectin-binding proteins mediating the adhesion of other microbial pathogens. In contrast, repeats common to both LigA and LigB do not bind these host proteins, and nonrepeat sequences in the carboxy-terminal domain of LigB show only weak interaction with fibronectin and fibrinogen. A functional role for the binding activity of LigA and LigB is suggested by the ability of the recombinants to inhibit leptospiral adhesion to fibronectin by 28% and 21%, respectively. The binding of LigA and LigB to multiple ligands present in different tissues suggests that these adhesins may be involved in the initial colonization and dissemination stages of leptospirosis. The characterization of the Lig adhesin function should aid the design of Lig-based vaccines and serodiagnostic tests.

The Liga Femenil Mexicanista was a social, cultural, political, and charitable organization for Mexican-American women, founded in Laredo in 1911 by Jovita Idar. It was modeled on the recently established Congreso Mexicanista. Several of the women operated their own schools and allowed the children of the poor to attend free of charge. The organization also provided food and clothing to the needy of the community. The liga's members came predominantly from the working class. Meetings were sometimes held at the home of Idar's parents, Jovita and Nicasio Idar. Nicasio Idar published news of the organization's activities in La Crnica. The liga also sponsored literary readings and theatrical productions to raise funds for its charities. Jovita Idar served as the organization's first president; other members included Mara de Jess De Len, Soledad Flores de Pea, Mara Rentera, and Mara Villarreal. The league is one of the first-known attempts by Mexican-American women to unite for a social and political cause, and it attracted the most educated women of the community. 17dc91bb1f

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