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Overview
Overview
We study stress, trauma, and various neuropsychiatric conditions, focusing not just on patients' symptoms, but on the underlying brain mechanisms that explain why they occur. Many of our current projects examine how physical and environmental factors—such as repeated trauma exposure, chronic pain, poor sleep quality, and metabolic diseases—fundamentally alter the brain's structural, functional, and metabolic networks, drawing on neuroimaging, clinical, and molecular biological perspectives. We use a variety of methods in our research, including multimodal neuroimaging, neuropsychological assessments and blood biomarker and gene analyses.
Explore my key papers as first or corresponding authors below to learn more about our work:
Astrocytic gamma-aminobutyric acid dysregulation as a therapeutic target for posttraumatic stress disorder
Signal Transduction and Targeted Therapy, 2025
[IF = 52.7]
https://doi.org/10.1038/s41392-025-02317-5
Distinctively different human neurobiological responses after trauma exposure and implications for posttraumatic stress disorder subtyping
[IF = 10.1]
https://doi.org/10.1038/s41380-023-01995-3
Variations in brain glutamate and glutamine levels throughout the sleep-wake cycle
[IF = 9.0]
https://doi.org/10.1016/j.biopsych.2024.11.016
Differential alterations in brain structural network organization during addiction between adolescents and adults
[IF = 5.5]
Impact of sleep disturbance in shift workers on hippocampal volume and psychomotor speed
[IF = 4.9]
https://doi.org/10.1093/sleep/zsae100
Additional lead-authored works:
Genetic profile for dopamine signaling predicts brain functional reactivity to repetitive transcranial magnetic stimulation
European Archives of Psychiatry and Clinical Neuroscience, 2023
https://doi.org/10.1007/s00406-022-01436-2
Gray matter volume reduction in the emotional brain networks in adults with anosmia
Journal of Neuroscience Research, 2022
Hippocampal subregional alterations and verbal fluency in the early stage of type 2 diabetes mellitus
European Journal of Neuroscience, 2021
Obesity may connect insulin resistance to decreased neuronal viability in human diabetic brain
Obesity, 2020
Changes in structural covariance among olfactory-related brain regions in anosmia patients
Experimental Neurobiology, 2024
Collaborative & co-authored works:
A double-hit of stress and low-grade inflammation on functional brain network mediates posttraumatic stress symptoms
Nature Communications, 2020
https://doi.org/10.1038/s41467-020-15655-5
Brain changes in overweight/obese and normal-weight adults with type 2 diabetes mellitus
Diabetologia, 2017
Diabetologia, 2017
https://doi.org/10.1007/s00125-017-4266-7
Network attributes underlying intellectual giftedness in the developing brain
Scientific Reports, 2017
Prefrontal white matter abnormalities associated with pain catastrophizing in patients with complex regional pain syndrome
Archives of Physical Medicine and Rehabilitation, 2021
Archives of Physical Medicine and Rehabilitation, 2021
FKBP5-associated miRNA signature as a putative biomarker for PTSD in recently traumatized individuals
Scientific Reports, 2020
Disturbed insular functional connectivity and its clinical implication in patients with complex regional pain syndrome
NeuroImage: Clinical, 2023
Aberrant resting-state functional connectivity in complex regional pain syndrome: a network-based statistics analysis
Experimental Neurobiology, 2023
Alterations in structural rich-club connectivity of the precuneus are associated with depressive symptoms among individuals with subjective memory complaints
Cognitive, Affective, & Behavioral Neuroscience, 2019
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