No cell lives in isolation. Instead, cells constantly communicate with each other and their environment via cell-to-cell signaling.
Our lab studies cells cell-to-cell signaling pathways, to understand how they regulate animal development.
Our current research focus is Notch signaling and its regulation of transcription (activation, dynamics) in the germline stem cells.
We use a multidisciplinary approach, combining biochemistry, genetics, molecular&cell biology, quantitative imaging, computational biology and statistics.
We use the nematode C. elegans as a model system, which allow us to analyze the cell signaling response in its native context at a single-molecule level.