Publication

2024

• Jaewoong Lee*, Arya Mani, Min-Jeong Shin, Ronald M. Krauss*. Leveraging altered Lipid Metabolism in treating B cell malignancies. Progress in lipid research. 2024 Jul 2:95:101288. doi:10.1016/j.plipres.2024.101288.

  • * Corresponding authors

  • Impact Factor (%): 0.4, Top-1 in JCR category 

  • BRIC, 한국을 빛낸 사람들 (한빛사) 등재 [2024] 

2023

• Mingli Li, Lu Yang, Anthony K.N. Chan, Sheela Pangeni Pokharel, Qiao Liu, Nicole Mattson, Xiaobao Xu, Wen-Han Chang, Kazuya Miyashita, Jun Wu, Jinhui Wang, Lai N. Chan, Jaewoong Lee, Xu Hannah Zhang, Steven T. Rosen, Markus Müschen, Jun Qi, Jianjun Chen, Kevin Him, Alexander J.R. Bishop, Chun-Wei Chen. Epigenetic control of protein translation and tumor progression via RUVBL1-EEF1A1 axis. Advanced Science. 2023 Apr 19;e2206584.

2022

• Jaewoong Lee. Does IFITM3 link inflammation to tumorigenesis? BMB Rep. 2022 Dec; 55(12):602-608.

• Jaewoong Lee, Mark E Robinson, Ning Ma, Kohei Kume, Dewan Artadji, Teresa Sadras, Kadriye Nehir Cosgun, Huimin Geng, Elisabeth M Paietta, Maike Buchner, Nagarajan Vaidehi, David M Weinstock, Markus Müschen . Structural Basis of Feedback Control of Oncogenic Signaling in B-Lymphoid Malignancies. Blood. 2022 138 (Supplement 1), 355-355 

• Kohei Kume, Zhengshan Chen, Lai N Chan, Mark E Robinson, Etienne Leveille, Jaewoong Lee, Kadriye Nehir Cosgun, David Fonseca Arce, Dhruv Khanduja, Lars Klemm, Markus Müschen . Divergent MYC-and BCL6-Driven Metabolic Programs Enable Dynamic Regulation of Cell Biomass in B-Cell Malignancies. Blood. 2022 140 (Supplement 1), 5900-5901 

• Ruifeng Sun, Jaewoong Lee, Tim Wartewig, Mark E Robinson, Alberto Bigogno, David Fonseca Arce, Abu-Sayeef Mirza, Andrew Takeda, Lars Klemm, Vivasvan Vykunta, Brian Shy, Alexander Marson, Markus Müschen. CD25 As Feedback Regulator of Oncogenic TCR Signaling in T-Cell Lymphoma. Blood. 2022 140 (Supplement 1), 5975-5976.

• Andrew Takeda, Jaewoong Lee, Tim Wartewig, Alberto Bigogno, David Fonseca Arce, Markus Müschen. IFITM3 Acts As a PIP3 Scaffold in TCR-PI3K Signaling. Blood. 2022 140 (Supplement 1), 3030-3031

• Kadriye Nehir Cosgun, Huda Jumaa, Mark E Robinson, Lai N Chan, Jaewoong Lee, Kohei Kume, David Fonseca Arce, Julia Jellusova, Markus Müschen. GSK3β Inhibition Is a Unique Vulnerability in Lymphoid Malignancies. Blood. 2022 140 (Supplement 1), 3114-3115

2021

• Humberto Contreras-Trujillo, Jiya Eerdeng, Samir Akre, Du Jiang, Jorge Contreras, Basia Gala, Mary C. Vergel-Rodriguez, Yeachan Lee, Aparna Jorapur, Areen Andreasian, Lisa Harton, Charles S. Bramlett, Anna Nogalska, Gang Xiao, Jae-Woong Lee, Lai N. Chan, Markus Müschen, Akil A. Merchant & Rong Lu. Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses. Nat Commun. 2021 Nov 11;12(1):6522.

• Lili Pan*, Chao Hong*, Lai N Chan*, Gang Xiao, Parmanand Malvi, Mark E. Robinson, Huimin Geng, Srinivasa T. Reddy, Jaewoong Lee, Vishal Khairnar1 Kadriye Nehir Cosgun, Liang Xu, Kohei Kume, Teresa Sadras, Shaoyuan Wang, Narendra Wajapeyee & Markus Müschen. PON2 subverts metabolic gatekeeper functions in B-cells to promote leukemogenesis. Proc Natl Acad Sci U S A. 2021 Feb 16;118(7). *These authors contributed equally to the study.

2020

• Jaewoong Lee, Mark E. Robinson, Ning Ma, Dewan Artadji, Mohamed A. Ahmed, Gang Xiao, Teresa Sadras, Gauri Deb, Janet Winchester, Kadriye Nehir Cosgun, Huimin Geng, Lai N. Chan, Kohei Kume, Teemu P. Miettinen, Ye Zhang, Matthew A. Nix, Lars Klemm, Chun Wei Chen, Jianjun Chen, Vishal Khairnar, Arun P. Wiita, Andrei Thomas-Tikhonenko, Michael Farzan, Jae U. Jung, David M. Weinstock, Scott R. Manalis, Michael S. Diamond, Nagarajan Vaidehi & Markus Müschen. IFITM3 functions as PIP3-scaffold to amplify PI3K signaling in B-cells. Nature. 2020 Dec;588(7838):491-497   

  • BRIC, 한국을 빛낸 사람들 (한빛사) 등재 [2000] 

  • 한빛사 인터뷰 

• Lai N Chan, Mark A Murakami, Mark E Robinson, Rebecca Caeser, Teresa Sadras, Jaewoong Lee, Kadriye Nehir Cosgun, Kohei Kume, Vishal Khairnar, Gang Xiao, Mohamed A Ahmed, Eamon Aghania, Gauri Deb, Christian Hurtz, Seyedmehdi Shojaee, Chao Hong, Petri Pölönen, Matthew A Nix, Zhengshan Chen, Chun Wei Chen, Jianjun Chen, Andreas Vogt, Merja Heinäniemi, Olli Lohi, Arun P Wiita, Shai Izraeli, Huimin Geng, David M Weinstock, Markus Müschen. Signalling input from divergent pathways subverts B cell transformation. Nature. 2020 Jul;583(7818):845-851.

2018

• Xiao G, Chan LN, Klemm L, Braas D, Chen Z, Geng H, Zhang QC, Aghajanirefah A, Cosgun KN, Sadras T, Lee J, Mirzapoiazova T, Salgia R, Ernst T, Hochhaus A, Jumaa H, Jiang X, Weinstock DM, Graeber TG, Müschen M. B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies. Cell. 2018 Apr 5;173(2):470-484.e18.

• Sullivan-Reed K, Bolton-Gillespie E, Dasgupta Y, Langer S, Siciliano M, Nieborowska-Skorska M, Hanamshet K, Belyaeva EA, Bernhardy AJ, Lee J, Moore M, Zhao H, Valent P, Matlawska-Wasowska K, Müschen M, Bhatia S, Bhatia R, Johnson N, Wasik MA, Mazin AV, Skorski T. Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells. Cell Rep. 2018 Jun 12;23(11):3127-3136.

2017

• Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, Pufall MA, Cazzaniga G, Liu GJ, Milne TA, Koeffler HP, Ross TS, Sánchez-García I, Borkhardt A, Yamamoto KR, Dickins RA, Graeber TG, Müschen M. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 2017 Feb 23;542(7642):479-483.

2015

• Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, Loh ML, Jung JU, Coligan JE, Bolland S, Mak TW, Limnander A, Jumaa H, Reth M, Weiss A, Lowell CA, Müschen M. Signaling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 2015 May 21;521(7552):357-61.

• Geng H, Hurtz C, Lenz KB, Chen Z, Baumjohann D, Thompson S, Goloviznina NA, Chen WY, Huan J, LaTocha D, Ballabio E, Xiao G, Lee JW, Deucher A, Qi Z, Park E, Huang C, Nahar R, Kweon SM, Shojaee S, Chan LN, Yu J, Kornblau SM, Bijl JJ, Ye BH, Ansel KM, Paietta E, Melnick A, Hunger SP, Kurre P, Tyner JW, Loh ML, Roeder RG, Druker BJ, Burger JA, Milne TA, Chang BH, Müschen M. Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia. Cancer Cell. 2015 Mar 9;27(3):409-25.

2013

• Cramer-Morales K, Nieborowska-Skorska M, Scheibner K, Padget M, Irvine DA, Sliwinski T, Haas K, Lee J, Geng H, Roy D, Slupianek A, Rassool FV, Wasik MA, Childers W, Copland M, Müschen M, Civin CI, Skorski T. Personalized synthetic lethality induced by targeting RAD52 in leukemias identified by gene mutation and expression profile. Blood 2013 Aug 15;122(7):1293-304.

2008-2012

• Jae-Woong Lee, Hyeng-Soo Kim, Seonggon Kim, Junmo Hwang, Young Hun Kim, Ga Young Lim, Wern-Joo Sohn, Suk-Ran Yoon, Jae-Young Kim, Tae Sung Park, Seung Hwan Oh, Kwon Moo Park, Zae Young Ryoo, Sanggyu Lee. Regulation of HOXA9 activity by predominant expression of DACH1 against C/EBPα and GATA-1 in myeloid leukemia with MLL-AF9. Biochem Biophys Res Commun. 2012 Sep 28;426(3):299-305.

• Jae-Woong Lee, Hyeng-Soo Kim, Seonggon Kim, Junmo Hwang, Young Hun Kim, Ga Young Lim, Wern-Joo Sohn, Suk-Ran Yoon, Jae-Young Kim, Tae Sung Park, Kwon Moo Park, Zae Young Ryoo, Sanggyu Lee. DACH1 regulates cell cycle progression of myeloid cells through the control of cyclin D, Cdk 4/6 and p21Cip1. Biochem Biophys Res Commun. 2012 Mar 30;420(1):91-5.

• Lee JW*, Kim E*, Baek DC, Lee SR, Kim MS, Kim SH, Kim CS, Ryoo ZY, Kang HS, Chang KT. *These Two authors contributed equally to this study. Processing and subcellular localization of ADAM2 in the Macaca fascicularis testis and sperm. Anim Reprod Sci. 2010 Jan;117(1-2):155-9.

• Kim HS, Hwang J, Kim YH, Kim S, Lee JW, Kang HS, Kim KS, Ha JH, Chung JW, Chang KT, Ryoo ZY, Lee S. Detection of low-abundant novel transcripts in mouse hematopoietic stem cells. Mol Genet Genomics. 2009 Oct;282(4):363-70.

• Kim E, Park KE, Kim JS, Baek DC, Lee JW, Lee SR, Kim MS, Kim SH, Kim CS, Koo DB, Kang HS, Ryoo ZY, Chang KT. Importance of the porcine ADAM3 disintegrin domain in sperm-egg interaction. J Reprod Dev. 2009 Apr;55(2):156-62.

• Kim E, Lee JW, Baek DC, Lee SR, Kim MS, Kim SH, Imakawa K, Chang KT. Identification of novel retromer complexes in the mouse testis. Biochem Biophys Res Commun. 2008 Oct 10;375(1):16-21.