Laboratory of Aquaculture and Marine Ecophysiology
Integrative Neuroendocrinology of Fish Reproduction • Applications in Aquaculture • Ecotoxicology •
Biodiversity • Conservation • Sustainability
Integrative Neuroendocrinology of Fish Reproduction • Applications in Aquaculture • Ecotoxicology •
Biodiversity • Conservation • Sustainability
This research line investigates the neuroendocrine mechanisms that regulate reproduction in teleost fishes, with emphasis on the functional dynamics of the brain–pituitary–gonadal (BPG) axis and its interactions with central and peripheral modulatory systems. The molecular and cellular bases of gametogenesis, steroidogenesis, and sexual differentiation are addressed through integrated histological, immunohistochemical, endocrine, and gene expression analyses. A comparative perspective allows the identification of evolutionarily conserved patterns and species-specific physiological adaptations. Interfaces between hormonal regulation, reproductive plasticity, and social behavior are also examined. The overarching goal is to understand how internal signals and environmental variables converge to modulate reproductive competence and maintain endocrine system stability.
This research line evaluates the impacts of environmental contaminants and anthropogenic stressors on the functional integrity of endocrine and metabolic systems in aquatic organisms. It investigates alterations in molecular biomarkers, oxidative parameters, hormonal profiles, and behavioral performance resulting from exposure to metals, pharmaceuticals, and emerging pollutants. The approach integrates comparative physiology, experimental toxicology, and behavioral analysis to elucidate mechanisms of endocrine disruption. The consequences of these disturbances on reproduction, growth, and energy homeostasis are explored. This line contributes to understanding ecotoxicological risks in aquatic ecosystems and to the development of physiological indicators of environmental quality.
Focused on the interface between basic physiology and productive application, this research line develops and refines protocols for reproductive induction in captivity, including hormonal manipulation, assessment of gamete quality, and monitoring of embryonic and larval development. It investigates the physiological determinants of gonadal maturation, fertilization, and larval viability under controlled conditions. Morphological, endocrine, and molecular techniques are integrated to optimize the reproductive performance of species of aquaculture and conservation interest. The line also addresses challenges associated with reproductive dysfunction in captivity and strategies for its mitigation. The results support sustainable production programs and restocking initiatives for threatened species.
This research line examines metabolic regulation associated with lipid nutrition, with emphasis on the dynamics of essential fatty acids (DHA, EPA, ARA) and their influence on growth, hepatic function, and reproductive performance. It investigates the modulation of metabolic pathways and gene expression in response to different dietary compositions and thermal variations. Interactions among lipid profile, energy homeostasis, and physiological plasticity are analyzed. The approach integrates biochemistry, molecular physiology, and histomorphological analyses to understand the systemic effects of diet. The findings provide a scientific basis for the formulation of functional diets and for improving productive efficiency in sustainable aquaculture systems.
Office and Laboratory
University of São Paulo – IB/USP
Universidade de São Paulo - IB/USP
Rua do Matão, trav. 14, no. 321,r
Cidade Universitária, São Paulo - SP
Zip Code: 05508-090 - Brazil
Other affiliation
Graduate Program in Aquaculture and Sustainable Development
Federal University of Paraná – PGADS/UFPR
Rua Pioneiro, 2153
Palotina - PR
Zip Code: 85950-000 - Brazil
Contact
honjijp@usp.br
honjijp@gmail.com
honji@ufpr.br
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