2025
29. Kim, N #., KIm, M. #, Jeong, E., Yeo, J., Kim, B., Myung, K., Schärer, O. D., and Lee, K. Y.* 2025. Proteomic discovery of DEK and NUMA1 as new players in UV-induced DNA damage repair mechanisms. Cell Death Discovery. 11 (1), 547.
2024
28. Kim, S #., Park, S. H.#, Myung, K., and Lee, K. Y.* 2024. Lamin A/C facilitates DNA damage response by modulating ATM signaling and homologous recombination pathways. Animal Cells and Systems. 28 (1), 401-416.
27. Kim, S., Park, S. H., Kang, N., Ra, J. S., Myung, K.*, and Lee, K. Y.* 2024. Polyubiquitinated PCNA triggers SLX4-mediated break-induced replication in alternative lengthening of telomeres (ALT) cancer cells. Nucleic Acids Research. 52 (19), 11785-11805.
2023
26. Park, S. H. #, Kim, N. #, Kang, N., Ryu, E., Lee, E. A., Ra, J. S., Gartner, A., Kang, S., Myung, K, Lee, K. Y.* 2023. Short-range end resection requires ATAD5-mediated PCNA unloading for faithful homologous recombination. Nucleic Acids Research. 51 (19), 10519-10535.
25. Kim, S., Kim, Y., Kim, Y., Yoon, S., Lee, K. Y., Lee, Y., Kang, S., Myung, K., Oh, C. K. 2023. PCNA Ser46-Leu47 residues are crucial in preserving genomic integrity. Plos one. 18(5): e0285337.
2021
24. Park, S. H. #, Kim, Y. Y. #, Ra, J. S., Wie, M., Kang, M, S., Kang, S., Myung, K, Lee, K. Y.* 2021. Timely termination of repair DNA synthesis by ATAD5 is important in oxidative DNA damage-induced single-strand break repair. Nucleic Acids Research. 49 (20), 11746-11764.
23. Park, S. H. #, Kim, S. J. #, Myung, K, Lee, K. Y*. 2021. Characterization of subcellular localization of eukaryotic clamp loader/unloader and its regulatory mechanism. Scientific Reports. 11 (1), 1-16.
22. Kang, H. J., Cheon, N. Y., Park, H., Jeong, G. W., Ye, B. J., Yoo, E. J., Lee, J. H., Hur, J. H., Lee, E. A., Kim, H., Lee, K. Y., Choi, S. Y., Lee-Kwon W., Myung, K., Lee, J. Y., Kwon, H. M. 2021. TonEBP recognizes R-loops and initiates m6A RNA methylation for R-loop resolution. Nucleic Acids Research. 2021. 49(1):269-284.
2020
21. Lee, K. Y.* Park, S.H. Eukaryotic clamp loaders and unloaders in the maintenance of genome stability. 2020. Exp. Mol. Med. 2020. 52(12):1948-1958.
20. Kim, S. J.#, Wie, M. #, Park, S. H., Kim, T. M., Park, J. H., Kim, S., Myung, K.*, and Lee, K. Y.* 2020. ATAD5 Suppresses Centrosome Over-Duplication by Regulating UAF1 and ID1. Cell cycle. doi: 10.1080.
19. Kim, S., Kang, N., Park, S. H., Wells, J., Hwang, T., Ryu, E., Kim, B, G., Hwang, S., Kim, S, J., Kang, S., Lee, S., Stirling, P., Myung, K., and Lee, K. Y.* 2020. ATAD5 restricts R-loop formation through PCNA unloading and RNA helicase maintenance at the replication fork. Nucleic Acids Research. 48(13):7218–7238.
2019
18. Park, S. H., Kang, N., Song, E., Wie, M., Lee, E. A., Hwang, S., Lee, D., Ra, J. S., Park, I. B., Park, J., Kang, S., Park, J. H., Hohng, S., Lee, K. Y.,* and Myung, K*. 2019. ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress. Nature Communications. 10.1038/s41467-019-13667-4.
17. Kang, H. J., Park, H., Yoo, E. J., Lee, J. H., Choi, S. Y., Lee-Kwon, W., Lee, K. Y., Hur, J-H, Seo, J. K., Ra, J. S., Lee E. A., Myung, K., Kwon, H. M. 2019. TonEBP Regulates PCNA Polyubiquitination in Response to DNA Damage through Interaction with SHPRH and USP1. iScience. 19:177-190.
16. Kang, M, S.#, Ryu, E#, Lee, S. W.#, Park, J., Ha, N. Y., Ra, J. S., Kim, Y. J., Kim, J., Abdel-Rahman, M., Park, S. H., Lee, K. Y., Kim, H., Kang, S., and Myung, K. 2019. Regulation of PCNA cycling on replicating DNA by RFC and RFC-like complexes. Nature Communications. 10(2410).
2004-2013
15.Lee, K. Y., Fu, H., Aladjem, M., and Myung, K. 2013. ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin. Journal of Cell Biology 200(1):31-44.
14. Fox, J. T., Lee, K. Y., Myung, K., 2011. Dynamic regulation of PCNA ubiquitylation/ deubiquitylation. FEBS letter 585(18):2780-5.
13. Hendel, A., Krijger, P. H., Diamant, N., Goren, Z., Langerak, P., Kim, J., Reißner, T., Lee, K. Y., Geacintov, N. E., Carell, T., Myung, K., Tateishi, S., D'Andrea, A., Jacobs, H., Livneh, Z. 2011. PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells. PLoS Genetics 7(9):e1002262.
12. Bell, D.W., Lee, K. Y.#, Sikdar, N.#, Price, J.C.#, Chatterjee, R., Park, H-D., Fox, J., Ishiai, M., Rudd, M.L., Pollock, L. M., Fogoros, S. K., Mohamed, H., Hanigan, C. L., NISC Comparative Sequencing Program, Zhang, S., Cruz, P., Renaud, G., Hansen, N. F., Cherukuri, P. F., Borate, B., McManus, K. J., Stoepel, J., Sipahimalani, P., AndGodwin, A. K., Sgroi, D. C., Merino, M. J., Elliot, G., Elkahloun, A., Vinson, C., Takata, M., Mullikin, J. C., Wolfsberg, T.G., Hieter, P., Lim, D.S., Myung, K., 2011. Predisposition to Cancer Caused by Genetic and Functional Defects of Mammalian Atad5. PLoS Genetics 7(8): e1002245.
11. Krijger, P.#, Lee, K. Y.#, Wit, N., Berk, P., Wu, X., Roest, H. P., Maas, A., Hao Ding, H., Hoeijmakers, J., Myung, K., and Jacobs, H. 2011. HLTF and SHPRH are not essential for PCNA polyubiquitination, survival and somatic hypermutation: Existence of an alternative E3 ligase. DNA repair 10(4):438-4. (* represent equal contribution).
10. Lee, K. Y., Yang, K., Cohn, M. A., Sikdar, N., D’Andrea, A. D., and Myung, K. 2010. Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through its interactions with PCNA and USP1. J. Biol. Chem. 285(14):10362-9.
9. Sikdar, N.#, Banerjee, S.#, Lee, K. Y., Wincovitch, S., Pak, E., Nakanishi, K., Jasin, M., Dutra, A., Myung, K. 2009. DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity. Cell Cycle 8(19): 3199-207. (* represent equal contribution).
8. Motegi, A.#, Liaw, H.J.#, Lee, K. Y., Roest, H.P., Maas, A., Wu, X., Moinova, H., Markowitz, S.D., Ding, H., Hoeijmakers, J.H., Myung, K. 2008. Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks. Proc Natl Acad Sci U S A. 105(34):12411-6.
7. Lee, K. Y. and Myung, K. 2008. PCNA modifications for regulation of post-replication repair pathways. Mol Cells. 26(1):5-11
6. Lee, K. Y.#, Choi, Y. I.#, Kim, J., Choi, J. W., Sohn, D. H., Lee, C., Jeon, S. H., and Seong, R. H. 2007. Downregulation of the SWI/SNF chromatin remodeling activity by T-cell receptor signaling is required for proper thymocyte maturation. J Immunol. 178(11):7088-96. (* represent equal contribution).
5. Sohn, D. H., Lee, K. Y., Lee, C., Oh, J., Chung, H., Jeon, S. H., and Seong, R. H. 2007. SRG3 interacts directly with and stabilizes the major components of the SWI/SNF chromatin remodeling complex. J Biol Chem. 282(14):10614-24.
4. Jang, J., Choi, Y. I., Choi, J., Lee, K. Y., Chung, H., Jeon, S. H., Seong, R. H. 2006. Notch1 confers thymocytes a resistance to GC-induced apoptosis through Deltex1 by blocking the recruitment of p300 to the SRG3 promoter. Cell Death Differ. 13(9):1495-505.
3. Ahn, J., Ko, M., Lee, K. Y., Oh, J., Jeon, S. H., Seong, R. H. 2005. Expression of SRG3, a core component of mouse SWI/SNF chromatin-remodeling complex, is regulated by cooperative interactions between Sp1/Sp3 and Ets transcription factors. Biochem Biophys Res Commun. 338(3):1435-46.
2. Jeong, S. M., Lee, K. Y., Shin, D., Chung, H., Jeon, S. H., Seong, R.H. 2004. Nitric oxide inhibits glucocorticoid-induced apoptosis of thymocytes by repressing the SRG3 expression. J. Biol. Chem. 279(33):34373-9.
1. Ko, M., Jang, J., Ahn, J., Lee, K. Y., Chung, H., Jeon, S. H., Seong, R. H. 2004. T cell receptor signaling inhibits glucocorticoid-induced apoptosis by repressing the SRG3 expression via Ras activation. J. Biol. Chem. 279(21):21903-15.