Research
under construction (tbu)
Raman-based cell sorting
Function based cell sorting
Relevant papers
K.S. Lee et al., MicrobioRaman: An open-access web repository for microbiological Raman spectroscopy data. Nature Microbiology 9, 1152-1156 (2024).
A. Riva, ..., K.S. Lee et al., Identification of inulin-responsive bacteria in the gut microbiota via multi-modal activity-based sorting. Nature Communications 14, 8210 (2023).
K.S. Lee et al., Raman microspectroscopy for microbiology. Nature Reviews Methods Primers 1, 80 (2021).
K.S. Lee et al., Optofluidic Raman-activated cell sorting for targeted genome retrieval or cultivation of microbial cells with specific functions. Nature Protocols 16, 634–676 (2021).
F.C. Pereira, ..., K.S. Lee et al., Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization. Nature Communications 11, 5104 (2020).
K.S. Lee et al., An automated Raman-based platform for the sorting of live cells by functional properties. Nature Microbiology 4, 1035-1048 (2019).
Phenotyping microorganims
Cell ecophysiology; Bioproduction
Relevant papers
U. Alcolombri, ..., K.S. Lee et al., Sinking enhances the degradation of organic particles by marine bacteria. Nature Geoscience 14, 775–780 (2021).
C. Gao, ..., K.S. Lee et al., Single-cell bacterial transcription measurements reveal the importance of dimethylsulfoniopropionate (DMSP) hotspots in ocean sulfur cycling. Nature Communications 11, 1942 (2020).
L. Behrendt, ..., K.S. Lee et al., PhenoChip: A single-cell phenomic platform for high-throughput photophysiological analyses of microalgae. Science Advances 6, eabb2754 (2020).
Pathogens detection using Raman nanoprobes
surface-enhanced Raman scattering (SERS) nanoprobes
Reconfigurable optofluidic cell sorting platform
Refractive-index-based cell sorting
Engineered platform for oceanography/limnology
Water sampler