Research Area

Broadly my research interest lies into Microelectronics and MEMs technology. Currently I am working in area of Lab-on-chip development for blood component analysis. I am working to develop a microfluidic system which can detect optically tagged circulating tumor cells in single cell format which can be further separated from healthy blood cells and processed.

The problem can be divided into two parts-

1. Successful detection of CTCs in microchannel by metabolic labeling method

2. Isolate droplet encapsulated CTCs by coalescence with co-flow stream based on detected signal

Currently, We are working on detection of CTCs in hydro-dynamically focused stream. We are trying to develop metabolic labeling protocol comparable to standard CTC labeling protocol. Also, we are looking into optimization parameters for tagging, how signal intensity is changing with respect to every protocol parameter. We expect this protocol to be prominent candidate in future opto-microfluidics based CTCs detection as it has potential to detect majority kinds of tumor cells.