I was on this panel last year and have been focusing on stuff that came out since then or that I've discovered since then, particularly works by trans fem creators and with sapphic or trans fem content.
For books I've got Vivian Valentine's Amelia Temple series of Nancy Drew meets X-files meets Lovecraftian horror.
Beneath Strange Lights (Amelia Temple #1) from 2020
Against Fearful Lies (Amelia Temple #2) from 2024
Jessica Conwell's sequel to Ghost Flower: They Who Bring the Light - which has the agender spawn of a chthonic deity introduced in ghost flower joining a group of queer anarchists to thwart a conversion therapy group in Seattle
Ghost Flower 2022
Ghost Flower: They Who Bring the Light from 2024
Also notable, Conwell's earlier novels Cluster and Three Sharp Knives feature trans and other LGBTQ+ characters and are established to exist in the same universe as the Ghost Flower stories.
Kara Buchanan's Magica Riot from this year as well as Flight of the Scarlets by Susan Jane Bigelow from last year are magical girl stories where the protagonist is a trans woman or trans teen respectively.
There are a few other books from recent years as well, I have in mind, and while I think I mentioned it at last year's panel, I particularly liked Bang Bang Bodhisattva by Aubrey Wood, which is a noir cyberpunk story which sort of mixes up queer found family with Blade Runner (and cyborgs rather than androids).
For new works in graphic novels I liked Lilah Sturges' The Science of Ghosts. Magdalene Vissagio's Girlmode is a YA slice of life coming of age romance with a geeky trans girl protagonist but isn't directly SFF/horror for genre (in text only works, Alyson Greaves' How To Fly is another excellent work of that type that came out this summer.)
In comics, I've got Marvel Unlimited and have found Avengers Academy: Marvel Voices Unlimited Infinity to be the queerest thing out there in Marvel at the moment. Among other things it has adopted Charlie Jane Anders' Sheila Sexton/Escapade (a trans girl formerly of the New Mutants) and put her in a budding relationship with Brielle Brooks - Blade's daughter Bloodline.
The X-Men titles have always had queer subtext which had become more supertext over the past decade or so, particularly during the recently concluded Krakoa era. In the post Krakoa, From the Ashes era the queerer X-titles appear to be NYX - which is very queer mutant found family in Manhattan, and Exceptional X-Men, which among other things, has Kitty Pryde's bisexuality more directly addressed, along with the Dazzler solo series. X-Force does have sapphic couple Rachel Summers and Betsy Braddock and a couple of the new characters in Gail Simone's Uncanny X-men are varying flavors of LGBTQ+ as well.
Star Trek Discovery, the queerest Trek, wrapped this year and we finally had more directly queer relationships in the MCU in Agatha All Along.
In animation, not for the kids, but definitely for queer adults are Vivziepop's Hazbin Hotel and Helluva Boss.
In bad trends we've seen some cowardice from studios/distributors regarding transgender representation. Disney's dropping of the Moon Girl & Devil Dinosaur episode featuring Indya Moore's trans girl volleyball player as the focal point character with an opposing coach TERF antagonist is a big loss, as is the cis-washing of the character in the new Pixar series "Win or Lose".