Area of Research

I work on the optimization of fluorescent imaging rHDL nanoparticles to help facilitate the administration of neuroprotective agents for the prevention of glaucoma. Two fluorescent dyes with spectral overlap are incorporated into the rHDL nanoparticle system as a successful FRET pair. These dual fluorescent rHDL nanoparticles will help elucidate the in vivo kinetics for targeted payload release of the loaded particles and post-payload distribution of the empty nanoparticles. The development of these nanoparticles will hopefully aid in the protection of progressive retinal ganglion cell (RGC) loss in the eye, providing more treatment options of the millions of people suffering from glaucoma worldwide.