Professional Experience

• 2022/9-current: Director, Ph.D. Program of Interdisciplinary Medicine

• 2021/2-current: Joint Appointment Professor, Department of Life Sciences and Institute of Genome Sciences, National Yang Ming Chiao Tung University

• 2021/2-current: Professor, Institute of Biomedical Informatics, National Yang Ming Chiao Tung University

• 2019/9-2021/1: Joint Appointment Professor, Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University

• 2018/2-2021/1: Professor, Institute of Biomedical Informatics, National Yang-Ming University

• 2018/2-2020/7: Director, Information and Communication Center, National Yang-Ming University

• 2018/8-2019/7: Acting Director, Institute of Biomedical Informatics, National Yang-Ming University

• 2017/7-2019/1: Acting Director, Office of Institutional Research, National Yang-Ming University

• 2017/1-2018/4: Section Chief, Academic Information, Office of Academic Affairs, National Yang-Ming University

• 2014/2-2018/1: Associate Professor, Institute of Biomedical Informatics, National Yang-Ming University

• 2006/8-2014/1: Assistant Professor, Institute of Biomedical Informatics, National Yang-Ming University

• 2002/1-2006/7: Postdoctoral Fellow, Institute of Information Science, Academia Sinica

• 2001/6: Ph.D., Electrical Engineering, National Taiwan University

Journal Publications

1. J. Lee*, Y.H. Lin, P.K. Chiang, J.B. Lin, Y.T. Jan, W.K. Tsai, Y.J.Chen, K.P. Wu*. Androgen Deprivation Therapy–Induced Muscle Loss and Fat Gain Predict Cardiovascular Events in Prostate Cancer Patients. Journal of Cachexia, Sarcopenia and Muscle, 2025, https://doi.org/10.1002/jcsm.13844

2. Y.H. Weng, P.H. Chang, K.P. Wu, J.J. Lin*, T.S. Huang*. Enhanced personalized prediction of baseball-related upper extremity injuries through novel features and explainable artificial intelligence. Journal of Sports Sciences, 2025, 1-9, https://doi.org/10.1080/02640414.2025.2474328

3. J. Lee*, J.B. Lin, W.C. Lin, Y.T. Jan, Y.S. Leu, Y.J. Chen. K.P. Wu*. Identifying threshold of CT-defined muscle loss after radiotherapy for survival in oral cavity cancer using machine learning. European Radiology, 2024, 35:4289–4299, https://doi.org/10.1007/s00330-024-11303-4

4. P.C. Chen, P.K. Chiang, J.B. Lin, W.K. Tsai, W.C. Lin, Y.T. Jan, K.P. Wu, J. Lee*. Thresholds of Body Composition Changes Associated with Survival During Androgen Deprivation Therapy in Prostate Cancer. European Urology Open Science, 70, 99–108, 2024, https://doi.org/10.1016/j.euros.2024.10.007

5. W.C. Lin, C.S. Weng, A.T. Ko, Y.T. Jan, J.B. Lin, K.P. Wu*, J. Lee*. Interpretable machine learning model based on clinical factors for predicting muscle radiodensity loss after treatment in ovarian cancer. Support Care Cancer, 32:544, 2024, https://doi.org/10.1007/s00520-024-08757-z

6. W.Y. Huang, K.P. Wu*. SheddomeDB 2023: A Revision of an Ectodomain Shedding Database Based on a Comprehensive Literature Review and Online Resources. J. Proteome Res. 2023, 22:2570–2576, https://doi.org/10.1021/acs.jproteome.3c00001

7. W.H. Hsu, A.T. Ko, C.S. Weng, C.L. Chang, Y.T. Jan, J.B. Lin, H.J. Chien, W.C. Lin, F.J. Sun, K.P. Wu*, J. Lee*. Explainable machine learning model for predicting skeletal muscle loss during surgery and adjuvant chemotherapy in ovarian cancer. Journal of Cachexia, Sarcopenia and Muscle, 2023, https://doi.org/10.1002/jcsm.13282

8. J. Lee*, C.S. Weng, C.L. Chang, W.H. Hsu, Y.T. Jan, K.P. Wu*. Association of prognostic nutritional index with muscle loss and survival in patients with ovarian cancer treated with primary debulking surgery and chemotherapy. Support Care Cancer, 31:267, 2023.

9. J.Y. Lin, B.R. Juo, Y.H. Yeh, S.H. Fu, Y.T. Chen, C.L. Chen*, K.P. Wu*. Putative markers for the detection of early-stage bladder cancer selected by urine metabolomics. BMC Bioinformatics, 22:305, 2021.

10. Y.T. Wei, J.W. Wu, C.W. Yeh, H.C. Shen, K.P. Wu, I. Vida, C.C. Lien*. Morpho‐physiological properties and connectivity of vasoactive intestinal polypeptide‐expressing interneurons in the mouse hippocampal dentate gyrus. J Comp Neurol, 1–18, 2021.

11. J.Y. Lin, K.L. Kuo, Y.H. Kuo, K.P. Wu, K.C. Chu, Y.C. Jiang, Y.F. Chuang*, H.M. Cheng*. Association between real-world home blood pressure measurement patterns and blood pressure variability among older individuals with hypertension: A community-based blood pressure variability study. J Clin Hypertens, 00:1–10, 2020.

12. S.M. Chaw*, Y.C. Liu, Y.W. Wu, H.Y. Wang, C.Y.I. Lin, C.S. Wu, H.M. Ke, L.Y. Chang, C.Y. Hsu, H.T. Yang, E. Sudianto, M.H. Hsu, K.P. Wu, L.N. Wang, J.H. Leebens-Mack, I.J. Tsai*. Stout camphor tree genome fills gaps in understanding of flowering plant genome evolution. Nature Plants, 5(1):63–73, 2019.

13. W.S. Tien, P.M. Chen, C.Y. Chuang, S.M. Lui, H.C. Kuo, Y.J. Chen, K.P. Wu∗. Combining membrane proteomics and computational three-way pathway analysis revealed signalling pathways preferentially regulated in human iPSCs and human ESCs. Scientific Reports, 7(1):15055, 2017.

14. E.Y. Lai, Y.H. Chen, K.P. Wu∗. A knowledge-based T2-statistic to perform pathway analysis for quantitative proteomic data. PLoS Computational Biology, 13(6):e1005601, 2017.

15. D.C. Wu, K.Y. Wang, S.S.W. Wang, C.M. Huang, Y.W. Lee, M.I. Chen, S.A. Chuang, S.H. Chen, Y.W. Lu, C.C. Lin, K.W. Lee, W.H. Hsu, K.P. Wu∗, Y.J. Chen∗. Exploring the expression bar code of SAA variants for gastric cancer detection. Proteomics, 17(11):1600356, 2017.

16. C.H. Shao, C.L. Chen, J.Y. Lin, C.J. Chen, S.H. Fu, Y.T. Chen, Y.S. Chang, J.S. Yu, K.H. Tsui, C.G. Juo∗, K.P. Wu∗. Metabolite marker discovery for the detection of bladder cancer by comparative metabolomics. Oncotarget, 8:38802–38810, 2017.

17. W.S. Tien, J.H. Chen, K.P. Wu∗. SheddomeDB: the ectodomain shedding database for membrane-bound shed markers. BMC Bioinformatics, 18(Suppl 3):42, 2017.

18. W.H. Hou, N. Kuo, G.W. Fang, H.S. Huang, K.P. Wu, A. Zimmer, J.K. Cheng∗, C.C. Lien∗. Wiring Specificity and Synaptic Diversity in the Mouse Lateral Central Amygdala. Journal of Neuroscience, 36(16):4549–4563, 2016.

19. S.C. Chiang, C.L. Han, K.H. Yu, Y.J. Chen, K.P. Wu∗. Prioritization of cancer marker candidates based on the immunohistochemistry staining images deposited in the Human Protein Atlas. PLoS ONE, 8(11):e81079, 2013.

20. W.S. Tien, Y.T. Chen, K.P. Wu∗. SecretePipe: A screening pipeline for secreted proteins with competence to identify potential membrane-bound shed markers. Journal of Proteome Research, 12(3):1235–1244, 2013.

21. E.Y. Lai, W.B. Wang, T. Jiang, K.P. Wu∗. A linear-time algorithm for reconstructing zero-recombinant haplotype con€guration on a pedigree. BMC Bioinformatics, 13(Suppl 17):S19, 2012.

22. M.Y. Day, R.T.H. Tsai, C.L. Sung, C.C. Hsieh, C.W. Lee, S.H. Wu, K.P. Wu, C.S. Ong, W.L. Hsu. Reference Metadata Extraction Using a Hierarchical Knowledge Representation Framework. Decision Support Systems, 43(1):152–167, 2007.

23. W.T. Lin, W.N. Hung, Y.H. Yian, K.P. Wu∗, C.L. Han, Y.R. Chen, Y.J. Chen, T.Y. Sung∗, W.L. Hsu. Multi-Q: A Fully Automated Tool for Multiplexed Protein Quantitation. Journal of Proteome Research, 5(9):2328–2338, 2006.

24. K.P. Wu, J.M. Chang, J.B. Chen, C.F. Chang, W.J. Wu, T.H. Huang, T.Y. Sung, W.L. Hsu. RIBRA—An Error-Tolerant Algorithm for the NMR Backbone Assignment Problem, Journal of Computational Biology, 13(2):229–244, 2006.

25. H.N. Lin, K.P. Wu, J.M. Chang, T.Y. Sung, W.L. Hsu. GANA—A Genetic Algorithm for NMR Backbone Resonance Assignment, Nucleic Acids Research, 33(14):4593–4601, 2005.

26. H.N. Lin, J.M. Chang, K.P. Wu, T.Y. Sung, W.L. Hsu. HYPROSP II—A Knowledge-based Hybrid Method for Protein Secondary Structure Prediction Based on Local Prediction Confidence, Bioinformatics, 21(15):3227–3233, 2005.

27. K.P. Wu, H.N. Lin, J.M. Chang, T.Y. Sung, W.L. Hsu. HYPROSP: a Hybrid Protein Secondary Structure Prediction Algorithm—a Knowledge-based Approach, Nucleic Acids Research, 32(17):5059–5065, 2004.

28. K.P. Wu, S.J. Ruan, C.K. Tseng, F. Lai. Hierarchical Access Control Using the Secure Filter, IEICE Transactions on Information and Systems, E84-D(6):700–708, 2001.

29. K.P. Wu, Y.J. Joung. Asynchronous Group Mutual Exclusion in Ring Networks, IEE Proceedings-Computers and Digital Techniques, 147(1):1–8, 2000.