Zhang C, Shu L, Kim H, Khor TO, Wu R, Li W, Kong AT. Phenethyl isothiocyanate (PEITC) suppresses prostate cancer cell invasion epigenetically through regulating microRNA-194. Mol Nutr Food Res. 2016 Jan 28.

Guo Y, Yu S, Zhang C, Kong AN. Epigenetic regulation of Keap1-Nrf2 signaling. Free Radic Biol Med. 2015 Nov;88(Pt B):337-49.

Wu TY, Huang Y, Zhang C, Su ZY, Boyanapalli SSS, Khor TO, Wang H, Lin H, Gounder M, Kagan L, Androulakis IP, Kong ANT. Pharmacokinetics and pharmacodynamics of 3,3′-diindolylmethane (DIM) in regulating gene expression of phase II drug metabolizing enzymes. J. Pharmacokinetics and Pharmacodynamics. 2015 Aug;42(4):401-8.

Su ZY, Zhang C, Lee JH, Shu L, Wu TY, Khor TO, Conney AH, Lu YP, Kong AN. Requirement and Epigenetics Reprogramming of Nrf2 in Suppression of Tumor Promoter TPA-Induced Mouse Skin Cell Transformation by Sulforaphane. Cancer Prev Res (Phila). 2014 Mar;7(3):319-29.

Khor TO, Fuentes F, Shu L, Paredes-Gonzalez X, Yang AY, Liu Y, Smiraglia DJ, Yegnasubramanian S, Nelson WG, Kong AN. Epigenetic DNA Methylation of Antioxidative Stress Regulator NRF2 in Human Prostate Cancer. Cancer Prev Res (Phila). 2014 Dec;7(12):1186-97.

Wang L, Zhang C, Guo Y, Su ZY, Yang Y, Shu L, Kong AN. Blocking of JB6 Cell Transformation by Tanshinone IIA: Epigenetic Reactivation of Nrf2 Antioxidative Stress Pathway. AAPS J. 2014 Nov;16(6):1214-25.

Cheung KL, Lee JH, Shu L, Kim JH, Sacks DB, Kong AN. The Ras GTPase-activating-like Protein IQGAP1 Mediates Nrf2 Protein Activation via the Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Kinase (MEK)-ERK Pathway. J Biol Chem. 2013 Aug 2;288(31):22378-86.

Zhang C, Su ZY, Khor TO, Shu L, Kong AN. Sulforaphane Enhances Nrf2 Expression in Prostate Cancer TRAMP C1 Cells through Epigenetic Regulation. Biochem Pharmacol. 2013 May 1;85(9):1398-404. Epub 2013 Feb 14.

Wang, H., Khor, T.O., Yang, Q., Huang, Y., Wu, T.Y., Saw, C.L.L., Lin, W., Ioannis P. Androulakis, I.P. and Kong, A.N.T. Pharmacokinetics and Pharmacodynamics of Phase II Drug Metabolizing/Antioxidant Enzymes Gene Response by Anti-cancer Agent Sulforaphane in Rat Lymphocytes. Mol Pharm. 2012 Oct 1;9(10):2819-27. Epub 2012 Sep 11.

Lee JH, Khor TO, Shu L, Su ZY, Fuentes F, Kong AN. Dietary Phytochemicals and Cancer Prevention: Nrf2 Signaling, Epigenetics, and Cell Death Mechanisms in Blocking Cancer Initiation and Progression. Pharmacol Ther. 2013 Feb;137(2):153-71. Epub 2012 Oct 3.

Kim, J.H., Yu, S. Chen, J. D. and Kong, A.N. The nuclear cofactor RAC3/AIB1/SRC-3 enhances Nrf2 signaling by interacting with transactivation domains. Oncogene 2013 Jan 24;32(4):514-27. doi: 10.1038/onc.2012.59. Epub 2012 Feb 27.

Khor, T.O., Huang Y, Wu TY, Shu L, Lee J, Kong AN. Pharmacodynamics of curcumin as DNA hypomethylation agent in restoring the expression of Nrf2 via promoter CpGs demethylation. Biochem Pharmacol. 2011 Nov 1;82(9):1073-8. Epub 2011 Jul 20

Yu, S., Khor, T.O, Cheung, K.L., Li, W., Wu. T.Y., Huang, Y., Foster, B.A., Kan, Y.W., Kong, A.N.T. Nrf2 Expression Is Regulated by Epigenetic Mechanisms in Prostate Cancer of TRAMP Mice. PLoS One 2010 Jan 5;5(1):e8579.

Li, W., Thakor, N,, Xu, E.Y., Huang, Y., Chen, C., Yu, R., Holcik, M., Kong, A.N.T. An internal ribosomal entry site mediates redox-sensitive translation of Nrf2. Nucleic Acids Research 2010 Jan 1;38(3):778-88. Epub 2009 Nov 24.

Khor, T.O., Keum, Y.-S., Lin, W., Kim, J.H., Hu, R., Shen, G., Gopalkrishnan, A., Reddy, B., Zheng, X., Conney, A., and Kong, A.-N.T. Inhibitory Effects of Curcumin and Phenethyl isothiocyanate (PEITC) on the Growth of Human PC-3 Prostate Xenografts in Immunodeficient Mice. Cancer Res. 66(2):613-621, 2006 (Priority Report).

Li, W., Yu, S.-W., Yuan, X.-L., and Kong, A.-N.T. Nrf2 possesses a redox-sensitive NES in the Neh5 transactivation domain. J. Biol. Chem. Sep 15;281(37):27251-63, 2006. Epub Jun 21 2006.

Yu, R., Chen, C., Mo, Y., Hebbar, V., Owour, E.D., and Kong, A.-N.T. Activation of mitogen-activated protein kinase pathways induces antioxidant response element-mediated gene expression via Nrf2-dependent mechanism. J. Biol. Chem. 275: 39907-39913, December 22, 2000.

Petersen, D.D., Kong, ANT., Jorge, L.F., Nebert, D.W., and Arias, T.D. Debrisoquine polymorphism: Novel CYP2D6 gene BamHI RFLP in the Ngawbe Guaymi Indian of Panama. Pharmacogenetics 1:136-142, 1991.

Kong, AN, Ludwig, E., Slaughter, R., DiStefano, P., DeMasi, J., Middleton, E. and Jusko, W.J. Pharmacokinetics and pharmacodynamic modeling of direct suppression effects of methylprednisolone on serum cortisol and blood histamine in man. Clin. Pharmacol. Ther. 46: 616-628, 1989.

Kong, AN, and Jusko, W.J. Definitions and applications of mean transit/residence time to a two-compartment mammillary plasma clearance model. J. Pharm. Sci 43: 157-165, 1988.