Peer-Reviewed Journal Papers
Peer-Reviewed Journal Papers
Heo Y, Oh SS, Jung WB, Wehrli FW, Lee H, "Rapid Whole-Brain Venous Cerebral Blood Volume Mapping With 3D GRASE", NeuroImage 2025 In press.
Jo YY, Bae E, Yea JW, Park JW, Park J, Oh SA, Lee H. Assessment of the Effectiveness of a Visual Coaching Device Combined with Auditory Instructions on Reproducibility and Stability in Deep Inspiration Breath-Hold Radiotherapy. Journal of Clinical Medicine. 2025; 14(20):7259.
Kathryn M Jaroszynski, Hyunyeol Lee, Michael C Langham, Felix W Wehrli, "Comparison of Brain Oxygen Metabolic Parameters Between Constrained qBOLD and Whole-Brain Oximetric Methods at Baseline and in Response to a Physiologic Stimulus", NMR in Biomedicine 2025;38(9):e70120.
Won Jun Son, Sung Jun Ahn, Ji Young Lee, Hyunyeol Lee, "Automated Brain Segmentation on Computed Tomographic Images Using Perceptual Loss Based Convolutional Neural Networks", Investigative MRI 2024;28(4):193-201.
Brian-Tinh D Vu, Nada Kamona, Yohan Kim, Jonggang J Ng, Brandon C Jones, Felix W Wehrli, Hee Kwon Song, Scott P Bartlett, Hyunyeol Lee, Chanmith S Rajapakse, "Three Contrast in 3 min: Rapid, High-Resolution and Bone-Selective UTE MRI for Craniofacial Imaging With Automated Deep-Learning Skull Segmentation", Magn. Reson. Med. 2025;93(1):245-260.
Nada Kamona, Jonggan J Ng, Yohan Kim, Brian-Tinh D Vu, Arastoo Vossough, Connor S Wagner, Holly Cordray, Hyunyeol Lee, Dillan F Villavisanis, Chamith S Rajapakse, "Cranifacial Imaging of Pediatric Patients by Ultrashort Echo-Time Bone-Selective MRI in Comparison to CT", Acad. Radiol. 2024;31(11)4629-4642.
Jinwon Kim, Hyebin Lee, Sungsuk Oh, Jinhee Jang, Hyunyeol Lee, "Automated Quantification of Total Cerebral Blood Flow from Phase-Contrast MRI and Deep Learning", J. Imaging Info. Med. 2024; 37:563-574.
Rajiv S Deshpande, Michael C Langham, Hyunyeol Lee, Nada Kamona, Felix W Wehrli, "Quantification of Whole-Organ Individual and Bilateral Renal Metabolic Rate of Oxygen", Magn. Reson. Med. 2024;91(5):2057-2073.
Hyunyeol Lee, Jing Xu, Maria Fernandez-Seara, Felix W Wehrli, "Validation of a new 3D quantitative BOLD based cerebral oxygen extraction fraction mapping", J. Cereb. Blood Flow Metab. 2024; 44(7):1184-1198.
Nada Kamona, Brandon C Jones, Hyunyeol Lee, Hee Kwon Song, Chaith Rajapakse, Connor S Wagner, Scott P Bartlett, Felix W Wehrli, "Cranial bone imaging using ultrashort echo0tie bone-selective MRI as an alternative to gradient-echo based "black-bone" techniques", Magn. Reson. Mat. Phy. Biol. 2024;37:83-92.
Brian-Tinh D Vu, Brandon C Jones, Hyunyeol Lee, Nada Kamona, Rajiv S Deshpande, Felix W Wehrli, Chamith S Rajapakse, "Six-minute, in vivo MRI quantification of proximal femur trabecular bone 3D microstructure", Bone 2023; 177:116900.
Emma Biondetti, Junghun Cho, Hyunyeol Lee, "Cerebral Oxygen Metabolism from MRI Susceptibility", NeuroImage 2023; 276:120189.
Jones BC, Wehrli FW, Kamona N, Deshpande RS, Vu BD, Song HK, Lee H, Grewal RK, Chan TJ, et al., "Automated, Calibration-Free Quantification of Cortical Bone Porosity and Geometry in Postmenopausal Osteoporosis from Ultrashort Echo Time MRI and Deep Learning", Bone 2023; 171:116743.
Brandon Jones, Hyunyeol Lee, Cheng-Chieh Cheng, Al Mukaddam Mona, Hee Kwon Song, Peter Snyder, Nada Kamona, Chamith Rajapakse, Felix Wehrli, "MRI Quantification of Cortical Bone Porosity, Mineralization, and Morphology in Postmenopausal Osteoporosis", Radiology 2023; 307:2
Caporale AS, Barclay AM, Xu J, Hengyi Rao, Lee H, Langham MC, Detre JA, Wehrli FW, "Superior Sagittal Sinus Flow as a Proxy for Tracking Global Cerebral Blood Flow Dynamics Durin Wakefulness and Sleep", J. Cereb. Blood Flow Metab. 2023; 43(8):1340-1350.
Hyunyeol Lee, Felix W Wehrli, "Whole-Brain 3D Mapping of Oxygen Metabolism Using Constrained Quantitative BOLD", NeuroImage 2022; 250:118952.
Hyunyeol Lee, Jaeseok Park, "SNR-Enhanced, Rapid Electrical Conductivity Mapping Using Echo-Shifted MRI", Tomography 2022; 81(1):376-388.
Carrie E Zimmerman, Pulkit Khandelwal, Long Xie, Hyunyeol Lee, Hee Kwon Song, Paul A Yushkevich, Arastoo Vossough, Scott P Bartlett, Felix W Wehrli, “AutomaticSegmentation of Bone Selective MR Images for Visualization and Craniometry of the Cranial Vault”, Acad. Radiol. 2022;29(3):S98-S106.
Hyunyeol Lee, Felix W Wehrli, “Alternating Unbalanced SSFP for 3D R2’ Mapping of the Human Brain”, Magn. Reson. Med. 2021;85(5):2391-2402; Rapid Communication.
Brandon C Jones, Shaowei Jia, Hyunyeol Lee, Anna Feng, Snehal S Shetye, Alexandra Batzdorf, Nadav Shapira, Peter B Noel, Nancy Pleshko, Chamith S Rajapakse,“MRI-Derived Porosity Index is Associated with Whole-Bone Stiffness and Mineral Density in Human Cadaveric Femora”, Bone 2021;143:115774.
Alessandra Caporale, Hyunyeol Lee, Hui Lei, Hengyi Rao, Michael C Langham, John A Detre, Pei-Hsin Wu, Felix W Wehrli, “Cerebral Metabolic Rate of Oxygen(CMRO2) during Transition from Wakefulness to Sleep Measured with High Temporal Resolution OxFlow MRI with Concurrent EEG”, J. Cereb. Blood Flow Metab. 2021; 41(4):780-792.
Hyunyeol Lee, Xia Zhao, Hee Kwon Song, Felix W Wehrli, “Self-Navigated Three-Dimensional Ultrashort Echo Time Technique for Motion-Corrected Skull MRI”, IEEE T. Med. Imaging, 2020;39(9):2869-2880.
Hyunyeol Lee, Felix W Wehrli, “Venous Cerebral Blood Volume Mapping in the Whole Brain Using Venous-Spin-Labeled 3D Turbo Spin Echo”, Magn. Reson. Med. 2020;84(4):1991-2003.
Xia Zhao, Hyunyeol Lee, Hee Kwon Song, Cheng-Chieh Cheng, Felix W Wehrli, “Impact of Gradient Imperfections on Bone Water Quantification with Ultra-Short Echo Time MRI”, Magn. Reson. Med. 2020;84(4):2034-2047.
Rosaline Zhang, Hyunyeol Lee, Xia Zhao, Hee Kwon Song, Arastoo Vossough, Felix W Wehrli, Scott P Bartlett, “Bone-Selective MRI as a Nonradiative Alternative to CT for Craniofacial Imaging”, Acad. Radiol., 2020;27(11):1515-1522.
Erin K Englund, Maria A Fernandes-Seara, Ana E Rodriguez-Soto, Hyunyeol Lee, Zachary B Rodgers, Marta Vidorreta, John A Detre, Felix W Wehrli, “Calibrated fMRI for Dynamic Mapping of CMRO2 Responses Using MR-Based Measurements of Whole-Brain Venous Oxygen Saturation”, J. Cereb. Blood Flow Metab., 2020;40(7):1501-1516.
Suhyung Park, Liyong Chen, Jennifer Townsend, Hyunyeol Lee, David A Feinberg, “Simultaneous Multi-VENC and Simultaneous Multi-Slice Phase Contrast Magnetic Resonance Imaging”, IEEE T. Med. Imaging, 2020;39(3):742–752.
Hyunyeol Lee, Xia Zhao, Hee Kwon Song, Rosaline Zhang, Scott P Bartlett, Felix W Wehrli, “Rapid Dual-RF, Dual-Echo, Three-Dimensional Ultrashort Echo Time Craniofacial Imaging: A Feasibility Study”, Magn. Reson. Med., 2019;81(5):3007–3016.
Hyunyeol Lee, Erin K Englund, Felix W Wehrli, “Interleaved Quantitative BOLD: Combining Extravascular R2’- and Intravascular R2-Measurements for Estimation of Deoxygenated Blood Volume and Hemoglobin Oxygen Saturation”, NeuroImage, 2018;174(1):420–431.
Ana E Rodriguez-Soto, Osheiza Abdulmalik, Michael C Langham, Nadav Schwartz, Hyunyeol Lee, Felix W Wehrli, “T2-Prepared Balanced Steady-State Free Precession (bSSFP) for Quantifying Whole-Blood Oxygen Saturation at 1.5 T”, Magn. Reson. Med., 2018;79(4):1893–1900.
Hyunyeol Lee, Eung Yeop Kim, Chul-Ho Sohn, Jaeseok Park, “Rapid Whole-Brain Gray Matter Imaging Using Single-Slab Three-Dimensional Dual-Echo Fast Spin Echo: A Feasibility Study”, Magn. Reson. Med., 2017;78(5):1691–1699; Rapid Communication
Hyunyeol Lee, Michael C Langham, Ana E Rodriguez-Soto, Felix W Wehrli, “Multiplexed MRI Methods for Rapid Estimation of Global Cerebral Metabolic Rate of Oxygen Consumption”, NeuroImage, 2017;149(1):393–403.
Hyunyeol Lee, Chul-Ho Sohn, Jaeseok Park, “Current-Induced Alternating Reversed Dual-Echo-Steady-State for Joint Estimation of Tissue Relaxation and Electrical Properties”, Magn. Reson. Med., 2017;78(1):107–120.
Hyunyeol Lee, Woo Chul Jeong, Hyung Joong Kim, Eung Je Woo, Jaeseok Park, “Alternating Steady State Free Precession for Estimation of Current-Induced Magnetic Flux Density: A Feasibility Study”, Magn. Reson. Med., 2016;75(5):2009–2019.
Hyunyeol Lee, Jaeseok Park, “SNR-Optimized Phase-Sensitive Dual-Acquisition Turbo Spin Echo Imaging: A Fast Alternative to FLAIR”, Magn. Reson. Med., 2013;70(1):106-116.
Hyunyeol Lee, Eung Yeop Kim, Kyung-Sook Yang, Jaeseok Park, “Susceptibility-Resistant Variable-Flip-Angle Turbo Spin Echo Imaging for Reliable Estimation of Cortical Thickness: A Feasibility Study”, NeuroImage, 2012;59(1):377–388.
Jaeseok Park, Jinna Kim, Eunhye Yoo, Hyunyeol Lee, Jong-Hee Chang, Eung Yeop Kim, “Detection of Small Metastatic Brain Tumors: Comparison of 3D Contrast-Enhanced Whole-Brain Black-Blood Imaging and MP-RAGE Imaging”, Invest. Radiol., 2012;47(2):136–141.
Hyunyeol Lee, Jin-Suck Suh, Jaeseok Park, “Effectiveness of 32-Element Surface Coil Array for Accelerated Volume-Targeted Breath-Hold Coronary MRA”, JKSMRM;13(2):137–145.
Peer-Reviewed Conference Proceedings (select)
Wonjun Son, Jiyoung Lee, Sungjun Ahn, Hyunyeol Lee, "CT-Based Hippocampus Segmentation with Dual-Decoder Network (HDD-Net)", MICCAI 2025, Daejeon, Korea.
Eunseo Bae, Sungsuk Oh, Felix W Wehrli, Hyunyeol Lee, "Self-Correction of B0 Field Drift and k-space Trajectory Errors in Alternating Unbalanced SSFP for Robust R2 and R2’ Mapping", ISMRM 2025, Honolulu, USA; Power Pitch Presentation
Wonjun Son, Sungjun Ahn, Hyunyeol Lee, "Deep Learning Based Automated Brain Segmentation from Computed Tomography Scans", ISMRM 2024, Singapore; Digital Poster Presentation
Eunseo Bae, Sungsuk Oh, Hyunyeol Lee, "Feasibility of High-Speed R2 and R2' Mapping Via Alternating SSFP With View-Sharing", ISMRM 2024, Singapore; Digital Poster Presentation
Youngho Heo, Sungsuk Oh, Hyunyeol Lee, "Accelerated Whole-Brain Mapping of Venous Cerebral Blood Volume Using Velocity-Selective Venous-Spin-Labeling With 3D GRASE Encoding", ISMRM 2024, Singapore; Digital Poster Presentation
Jinwon Kim, Hyebin Lee, Jinhee Jang, Hyunyeol Lee, "Automatic Quantification of Total Cerebral Blood Flow from Phase-Contrast MRI Using Deep Learning", 31st ISMRM, Toronto, Canada; Digital Poster Presentation
Hyunyeol Lee, Jing Xu, Felix W Wehrli, "Validation of Constrained qBOLD-Based 3D CMRO2 Mapping with Repeatability Test and Hypercapnic Challenge", 31st ISMRM, Toronto, Canada; Power Pitch Presentation
Hyunyeol Lee, Jing Xu, Maria A Fernandez-Seara, Felix W Wehrli, "Comparison of Constrained Quantitative BOLD with Dual-Gas Calibrated BOLD for 3D Mapping of Cerebral Oxygen Extraction Fraction", 31st ISMRM, Toronto, Canada; Digital Poster Presentation
Hyunyeol Lee, Felix W Wehrli, "Whole-Brain 3D CMRO2 Mapping WIth Prior-Guided Quantitative BOLD", 30th ISMRM, London, England, 2022; Virtual Presentation.
Hyunyeol Lee, Felix W Wehrli, “Whole-Brain 3D Quantitative BOLD Mapping With Preliminary Estimation of R2’ and Venous Blood Volume”, 29th ISMRM, Virtual Conference, 2021; Oral Presentation.
Hyunyeol Lee, Dongyeop Han, Cheng-Chieh Cheng, Felix W Wehrli, “Alternating 3D Unbalanced SSFP With Z-Shimming for Background Field Corrected R2’ Measurement in the Human Brain”, 28th ISMRM, Virtual Conference, 2020.
Hyunyeol Lee, Xia Zhao, Hee Kwon Song, Rosaline Zhang, Scott P Bartlett, Felix W Wehrli, “Self-Navigated, Rapid 3D UTE for Motion-Robust Skull Imaging”, 27th ISMRM, Montreal, Canada, 2019; Power Pitch Presentation; The Best Scientific Trainee Contribution Award
Hyunyeol Lee, Felix W Wehrli, “Cerebral Venous Blood Volume Estimation Using Velocity-Selective Spin Labeling Prepared Single-Slab Three-Dimensional Turbo Spin Echo Imaging”, 27th ISMRM, Montreal, Canada, 2019; Digital Poster Presentation
Hyunyeol Lee, Felix W Wehrli, “Interleaved qBOLD: Combining Extravascular R2’ and Intravascular R2 Mapping for Improved Estimation of Brain Hemodynamic Parameters”, 26th ISMRM, Paris, France, 2018; Oral Presentation
Hyunyeol Lee, Xia Zhao, Hee Kwon Song, Rosaline Zhang, Scott P Bartlett, Felix W Wehrli, “Soild-State MRI as a Noninvasive Alternative to Computed Tomography for Craniofacial Imaigng”, 26th ISMRM, Paris, France, 2018; Power Pitch Presentation
Hyunyeol Lee, Erin K Englund, Ana E Rodriguez-Soto, John A Detre, Richard Schwab, Felix W Wehrli, “CMRO2 Changes During Sleep in Humans”, 26th ISMRM, Paris, France, 2018; Traditional Poster Presentation
Hyunyeol Lee, Cheng Li, Erin K Englund, Felix W Wehrli, “Quantitative BOLD With Interleaved Acquisitions for Estimation of Extravascular R2’ and Intravascular R2 With Phase-Sensitive CSF Suppression”, 25th ISMRM, Honolulu, USA, 2017; Oral Presentation
Hyunyeol Lee, Michael C Langham, Cheng Li, Ana E Rodriguez-Soto, Felix W Wehrli, “Multiplexed OxFlow for Rapid Estimation of Whole-Brain Oxygen Consumption at Rest and During Apneic Challenge”, 25th ISMRM, Honolulu, USA, 2017; Electronic Poster Presentation
Hyunyeol Lee, Jaeseok Park, “Whole-Brain Gray Matter Imaging Exploiting Single-Slab 3D Dual-Echo TSE With Relaxation Modulation”, 24th ISMRM, Singapore, 2016; Electronic Poster Presentation
Hyunyeol Lee, Jaeseok Park, “Current-Controlled Alternating Reversed DESS MREIT for Joint Estimation of Tissue Relaxation and Electrical Properties”, 23rd ISMRM, Toronto, Canada, 2015; Electronic Poster Presentation
Hyunyeol Lee, Chul-Ho Sohn, Woo Chul Jeong, Hyung Joong Kim, Eung Je Woo, Jaeseok Park, “Current-Controlled Alternating Steady State Free Precession for Rapid Conductivity Mapping”, 22nd ISMRM, Milan, Italy, 2014; Power Poster Presentation; Summa Cum Laude Merit Award
Hyunyeol Lee, Woo Chul Jeong, Hyung Joong Kim, Eung Je Woo, Jaeseok Park, “Bz-SNR-Enhanced Echo-Shifted Incoherent Steady State Imaging for Electrical Conductivity Mapping”, 21st ISMRM, Utah, USA, 2013; Traditional Poster Presentation
Hyunyeol Lee, Suhyung Park, Jaeseok Park, “Dual-Echo Single-Slab 3D Turbo Spin Echo Imaging for Highly Efficient Sub-Millimeter Whole-Brain Gray Matter Imaging”, 20th ISMRM, Melbourne, Australia, 2012; Traditional Poster Presentation; Magna Cum Laude Merit Award
Hyunyeol Lee, Jaeseok Park, “SNR-Optimized, Accelerated, Phase-Sensitive, Dual-Acquisition, Single-Slab 3D Turbo Spin Echo Imaging”, 19th ISMRM, Montreal, Canada, 2011; Oral Presentation
Hyunyeol Lee, Jin-Suck Suh, Jaeseok Park, “Reliable Cortical Thickness Estimation with Reduced Susceptibility-Induced Signal Loss and Inherent Blood Suppression in Single-Slab 3D Turbo Spin Echo Imaging”, 18th ISMRM, Stockholm, Sweden, 2010; Oral Presentation
Patents
Hyunyeol Lee, "APPARATUS AND METHOD OF GENERATING MAGNETIC RESONANCE IMAGING FOR PRECISELY MEASURING BRAIN OXYGEN METABOLISM", USA; Registered: 18/288730
Hyunyeol Lee, "Magnetic Resonance Imaging Apparatus for Measuring Magnetic Resonance Imaging Parameters and Method of Operating the Same", USA; Registered: 17/834512
Hyunyeol Lee, "복수의 자기공명영상 패러미터를 측정하는 자기공명영상 장치 및 그 동작 방법", Republic of Korea; Registered: 102475519
Hyunyeol Lee, "뇌산소대사 정밀측정을 위한 자기공명영상 생성 장치 및 방법", Republic of Korea; Registered: 102456246
Hyunyeol Lee, Xia Zhao, Hee Kwon Song, Felix W Wehrli, Scott P Bartlett; “Solid-State MRI as a Noninvasive Alternative to Computed Tomography”; USA; Pending (62679453)
Hyunyeol Lee, Jaeseok Park; “Magnetic Resonance Imaging System Using Magnetic Resonance Electrical Impedance Tomography And Method For Generating Conductivity Distribution Image”; USA; Registered: 10182739
Hyunyeol Lee, Jaeseok Park; “Magnet Resonance Imaging Device For Constructing Grey Matter Image Selectively And Method Using The Same”; Republic of Korea; Registered: 101310706
Hyunyeol Lee, Jaeseok Park; “Magnet Resonance Imaging System And Method For Generating Conductivity Distribution Image Using Magnetic Resonance Electrical Impedance Tomography”; Republic of Korea; Registered: 101650891
Hyunyeol Lee, Jaeseok Park; “Magnet Resonance Imaging System And Method For Generating Conductivity Distribution Image Using Magnetic Resonance Electrical Impedance Tomography”; Republic of Korea; Registered: 101580536
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