곽기혁 교수 B세포 연구실

B cell Activation and Tolerance (BAT)

B cell activation varies significantly in both magnitude and quality depending on multiple factors, including the surrounding microenvironment, antigen properties, and the host's genetic background. These factors collectively determine how effectively B cells mount appropriate immune responses. Nevertheless, the precise mechanisms that control this context-dependent regulation of B cell activation remain incompletely understood. Our research is focused on uncovering these underlying regulatory pathways, with the ultimate goal of translating these discoveries into innovative vaccine platforms and therapeutic strategies against immune-related disorders.

Research Interest

Our laboratory aims to identify novel molecular switches that regulate B cell activation and tolerance, and to elucidate their underlying mechanisms. Additionally, we seek to develop innovative platforms capable of controlling these molecular switches, ultimately aiming to create effective vaccine strategies and therapeutic solutions that enhance human health and well-being.

Philosophy of Education

Our lab nurtures curiosity and innovation, where student-driven research thrives under expert mentorship. By fostering bidirectional scholarly communication, we create an environment of shared learning and growth. Our core goal is cultivating students who surpass their mentors, shaping leaders ready to excel in every sphere.