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Below are some websites to help you with your research. You are not limited to these genetic conditions. Please ensure that the condition you choose has an identified gene associated with the disorder. Make sure you indicate which chromosome is involved with the genetic disorder you choose. A good search phrase is "on which chromosome is the _____ gene located".
Alabama Virtual Library Middle School Resouces: https://www.avl.lib.al.us/resources/middle-school
Try Britannica School: Middle, and Explora for Middle Schools!
Gregor Mendel is known as the Father of Genetics. He used garden peas to develop many of the principles of genetics that we still use today.
https://my.clevelandclinic.org/health/diseases/14083-hemophilia
Hemophilia is a genetic disorder that prevents the blood from clotting properly. You can read more about this disorder and how it is inherited from the Centers for Disease Control and Prevention.
Sickle Cell Disease is a condition that changes the shape of the red blood cells in a person's body. These sickle-shaped cells cannot easily pass through capillaries. They can block the vessels entirely, which decreases oxygen to that part of the body. Read more from the Sickle Cell Disease Association of America.
https://my.clevelandclinic.org/health/diseases/9358-cystic-fibrosis
Cystic Fibrosis is caused by an inherited defective gene, and causes a person to have thick, sticky mucous in the lungs that can lead to life-threatening infections and permanent damage. It can also affect other organs, such as the pancreas and digestive system.
https://sites.uab.edu/mgraylab/huntingtons-disease/
Huntington's Disease is caused by a mutation in the DNA and is passed on to future generations. It causes nerves in the brain to deteriorate early in life. This affects a person's mental abilities as well as how their body works, and makes it difficult to do regular daily activities.
https://forward.com/news/346566/transplanting-for-tay-sachs-its-a-decision-to-have-hope/
This is caused by a defect in the 15th chromosome that causes lipid build up in nerve cells in the brain. One in every 27 Jewish people in the United States is a carrier of this gene, and when a child has 2 copies it usually results in death by age 5.
Down Syndrome, also known as Trisomy 21, results when a person is born with 3 copies of the 21st chromosome instead of 2. This is the most common chromosomal condition in the United States, and how it affects a person varies greatly on an individual basis.
https://www.gettyimages.com/detail/photo/man-with-a-duchenne-muscular-dystrophy-sitting-in-a-royalty-free-image/107697939
This is a genetic condition that causes progressive muscle deterioration and weakness. It can make movements difficult, and eventually affect an individual's ability to breathe.
https://9jaflaver.com/see-the-new-look-of-teenager-after-removal-of-huge-tumor-on-his-face-photos/
Neurofibromatosis is a genetic disorder that causes tumors to form throughout the body. It is progressive and is one of the most common genetic diseases in the United States.
https://www.noonansyndrome.org.uk/
Noonan syndrome is a genetic disorder characterized by short stature, distinctive facial features, heart defects, bleeding problems and skeletal abnormalities.
https://www.cdc.gov/fragile-x-syndrome/related-concerns/index.html
Fragile X syndrome (FXS) is a genetic disorder that primarily affects males, causing intellectual disability, developmental delays, and behavioral problems. It is the most common inherited form of intellectual disability.
https://www.researchgate.net/figure/A-patient-with-Van-der-Woude-Syndrome-that-presented-with-CLP-and-bilateral-lip-pits_fig1_312365736
Van der Woude syndrome is a genetic disorder primarily characterized by the presence of small pits or depressions on the lower lip, often accompanied by a cleft lip and/or cleft palate; it's considered the most common genetic cause of cleft lip and palate.
Pompe disease, also known as glycogen storage disease type II, is a rare genetic disorder that affects the body's ability to break down glycogen, a type of sugar stored in muscles.
https://www.altamed.org/articles/take-control-your-diabetes
Diabetes is a chronic metabolic disorder that adversely affects the body's ability to manufacture and use insulin, a hormone necessary for the conversion of food into energy.
https://www.drmohanavamsyoncologist.com/blog/ovarian-cancer/
Some ovarian cancers cluster in families. These cancers are described as hereditary and are associated with inherited gene mutations.
https://www.nia.nih.gov/health/alzheimers-and-dementia/alzheimers-disease-fact-sheet
Alzheimer’s disease is a brain disorder that slowly destroys memory and thinking skills, and eventually, the ability to carry out the simplest tasks. Alzheimer’s is currently ranked as the seventh leading cause of death in the United States and is the most common cause of dementia among older adults.
Thalassemia is an inherited disease of faulty synthesis of hemoglobin. Your body may not make enough hemoglobin, which can lead to fewer healthy red blood cells. This leads to anemia, which can make you feel tired, weak, or short of breath.
Lupus is a chronic autoimmune disease that develops when the immune system attacks the body itself. The symptoms include fever, fatigue, weight loss, headache and muscle and joint pain that may come and go, but there is no cure for lupus.
https://www.geneticlifehacks.com/alopecia-areata-autoimmune-hair-loss-and-genetics/
Alopecia areata is a disorder characterized by loss of hair due to the immune system mistakenly attacking hair follicles, the tiny structures from which hairs grow.
https://www.abilitysuperstore.com/blogs/medical-articles/guide-by-condition-parkinsons-disease
Parkinson's disease is a chronic and progressive neurodegenerative disorder that affects movement, balance, and coordination.
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