Kapex Keto "It is now well established that estrogen modifies the transmission of the painful message in the brain, and, in addition, has a local activity in the cartilage, explains Professor Serge Perrot, of the Center for the evaluation and treatment of pain in Cochin hospital.
Kapex Keto Indeed, cells called chondrocytes are equipped with receptors sensitive to this hormone. The deep and permanent estrogen deficiency at the time of menopause therefore increases the sensitivity to pain in general, more particularly in the joints. "
Kapex Keto Menopausal women therefore more often suffer from stiffness, swelling and joint pain, particularly in the fingers and wrists. Can also be affected to a lesser extent, the knees, lumbar, shoulders, and more rarely the hips, feet and ankles. These pains may improve after stretching and a morning relax, but are mainly relieved by hormonal treatment of the menopause consisting in temporarily restoring a source of estrogen, if however other symptoms appear.
Kapex Keto The prognosis for patients depends on the type of pain. If remissions are observed, cases persist, in particular, in the fingers. "In these cases, it is a question of underlying osteoarthritis which seems to have started at the time of menopause," remarks Professor Bernard Cortet, head of the rheumatology department in Lille. Estrogens have a protective effect on cardiovascular risk, but also on the joint, without the links being entirely clear for this last aspect. Because not everything can be explained by the low concentration of estrogen receptors on chondrocytes. "
Kapex Keto In general, affected women can expect gradual regression of symptoms over a period of two to four years. Analgesics, anti-inflammatory drugs in short courses and non-medicinal means (thermal cures, sophrology) can help overcome certain pains. But above all, you have to lose weight if necessary and start or continue regular physical activity. "This is the best way to make your joints work and maintain them, in particular because of the risk of osteoporosis, that is to say of bone fragility which increases during menopause", recalls Serge Perrot.
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