*: co-first author; **: co-corresponding author
2025
Lee EJ*, Kim M*, Park S, Shim JH, Cho HJ, Park JA, Park K, Lee D, Kim JH, Jeong H, Matsuzaki F, Kim SY, Kim J, Yang H, Lee JS, Kim JW. (2025) Restoration of retinal regenerative potential of Müller glia by disrupting intercellular Prox1 transfer. Nature Commun 2928 (10.1038/s41467-025-58290-8).
Sim J, Park CE, Cho I, Min K, Eom M, Han S, Jeon H, Cho ES, Lee Y, Yun YH, Lee S, Cheon DH, Kim J, Kim M, Cho HJ, Park JW, Kumar A, Chong Y, Kang JS, Piatkevich KD, Jung EE, Kang DS, Kwon SK, Kim J, Yoon KJ, Lee JS, Kim CH, Choi, Kim JW, Song MR, Choi HJ, Boyden ES, Yoon YG, Chang JB. (2025) Nanoscale Resolution Imaging of Whole Mouse Embryos Using Expansion Microscopy. ACS Nano 9:7910-7927.
2024
Kim JW (2024) Transcription factors crossing the cell membrane. Nature Rev Mol Cell Biol. 25: 86. DOI: doi.org/10.1038/s41580-023-00667-y.
2023
Han JW, Chang HS, Yang JY, Choi HS, Park HS, Jun HO, Choi JH, Paik SS, Chung KH, Shin HJ, Nam S, Son JH, Lee SH, Lee EJ, Seo KY, Lyu J, Kim JW, Kim IB, Park TK. (2023) Intravitreal Administration of Retinal Organoids-Derived Exosomes Alleviates Photoreceptor Degeneration in Royal College of Surgeons Rats by Targeting the Mitogen-Activated Protein Kinase Pathway. Int J Mol Sci 24(15):12068.
Kim JM, Min KW, Kim YJ, Smits R, Basler K, Kim JW (2023) Wnt/β-Catenin Signaling Pathway Is Necessary for the Specification but Not the Maintenance of the Mouse Retinal Pigment Epithelium. Mol Cells 46: 441-450.
Park JW, Lee EJ, Moon E, Kim HL, Kim IB, Hodzic D, Kim N, Kweon HS, and Kim JW (2023) Orthodenticle homeobox 2 is transported to lysosomes by nuclear budding vesicles. Nature Commun 14: 1111.
Min KW, Kim N, Lee JH, Sung YH, Kim M, Lee EJ, Kim JM, Kim JH, Lee J, Cho W, Yang JM, Kim N, Kim J, Lee CJ, Lee SH, Lee HW, Kim JW (2023) Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant. Exp Mol Med, doi: 10.1038/s12276-023.
2022
Bae JH, Yang MJ, Jeong SH, Kim J, Hong SP, Kim JW, Kim YH, Koh GY (2022) Gatekeeping role of Nf2/Merlin in vascular tip EC induction through suppression of VEGFR2 internalization. Sci Adv 8: eabn2611.
Jeon HY, Choi J, Kraaier L, Kim YH, Eisenbarth D, Yi K, Kang JG, Kim JW, Shim HS, Lee JH, Lim DS (2022) Airway secretory cell fate conversion via YAP-mTORC1-dependent essential amino acid metabolism. EMBO J 41: e109365.
2021
Lim S, Kim YJ, Park S, Choi JH, Sung Y, Nishimori K, Kozmik Z, Lee HW, Kim JW (2021) mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia. eLife 10: e70079.
Kim YJ, Park S, Ha T, Kim S, Lim S, You H, Kim JW (2021) Retinoid Metabolism in the Degeneration of Pten-Deficient Mouse Retinal Pigment Epithelium. Mol Cells 44(8): 613-622.
Oh N, Park S, Kim JW, and Park JH (2021) Photothermal Transfection for Effective Nonviral Genome Editing. ACS Appl Biomaterials 4, 5678–5685.
Le D, Lim S, Min KW, Park JW, Kim Y, Ha T, Moon KH, Wagner KU, Kim JW (2021) Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity. Mol Cells 44:168-178.
Bae M, Roh JD, Kim Y, Kim SS, Han HM, Yang E, Kang H, Lee S, Kim JY, Kang R, Jung H, Yoo T, Kim H, Kim D, Oh H, Han S, Kim D, Han J, Bae YC, Kim H, Ahn S, Chan AM, Lee D, Kim JW, Kim E (2021) SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function. EMBO Mol Med. 13(2): e12632.
2020
You S*, Kim H*,**, Jung HY*, Kim B, Lee EJ, Kim JW, Kim Y**. (2020) Tuning surface functionalities of sub-10 nm-sized nanocarriers to target outer retina in designing drug delivery agents for intravitreal administration. Biomaterials 255:1 20188.
2019
Lee EJ, Kim N, Park JW, Kang KH, Kim WI, Sim NS, Jeong CS, Blackshaw S, Vidal M, Huh SO, Kim D, Lee JH, Kim JW. (2019) Global analysis of intercellular homeodomain protein transfer. Cell Rep 28: 712 – 722.
2018
Choi JH*, Jo HS*, Lim S, Kim HT, Lee KW, Moon KH, Ha T, Kwak SS, Lee EJ, Joe CO, Kim JW. (2018) mTORC1 accelerates retinal development via the immunoproteasome. Nature Comm 9: 2502.
Jeong SH, Kim HB, Kim MC, Lee JM, Lee JH, Kim JH, Kim JW, Park WY, Kim SY, Kim JB, Kim H, Kim JM, Choi HS, Lim DS. Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer. J Clin Invest 128: 1010 – 1025.
Moon KH, Kim JW. (2018) Hippo Signaling Circuit and Divergent Tissue Growth in Mammalian Eye. Mol Cells 41: 257 – 263 (review).
Moon KH, Kim HT, Lee D, Rao MB, Levine EM, Lim DS, and Kim JW. (2018) Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development. Dev Cell 44: 13 – 28.
2017
Park DY, Lee J, Kim J, Kim K, Hong SP, Han S, Kubota Y, Augustin H, Dr. Ding L, Kim JW, He Y, Adams R, and Koh GY (2017) Plastic roles of pericytes in the blood-retinal barrier. Nature Commun 8: 15296.
Ha T, Moon KH, Dai L, Hatakeyama J, Yoon K, Park HS, Kong YY, Shimamura K, and Kim JW. (2017) The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina. Cell Rep 19: 351–363.
Kim Y, Lim S, Ha T, Song YH, Sohn YI, Park DJ, Paik SS, Kim-Kaneyama JR, Song MR, Leung A, Levine EM, Kim IB, Goo YS, Lee SH, Kang KH, and Kim JW. (2017) The LIM protein complex establishes a retinal circuitry of visual adaptation by regulating Pax6 α-enhancer activity. eLife 6: e21303.
2016
Kim K, Kim IK, Yang JM, Lee E, Koh BI, Song S, Park J, Lee S, Choi C, Kim JW, Kubota Y, Koh GY, Kim I. (2016) SoxF Transcription Factors Are Positive Feedback Regulators of VEGF Signaling. Circ Res 119: 839 – 852.
Kwak SS*, Kang KH*, Kim S, Lee S, Lee JH, Kim JW, Byun B, Meadows GG, Joe CO. (2016) Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation. Cell Signal 28: 32-41.
Kim HT, Prochiantz A, Kim JW. (2016) Donating Otx2 to support neighboring neuron survival. BMB Rep. 49, 69-70.
2015
Park BY, Lee H, Woo S, Yoon M, Kim J, Hong Y, Lee HS, Park EK, Hahm JC, Kim JW, Shin SS, Kim MY, Yoon M. (2015) Reduction of Adipose Tissue Mass by the Angiogenesis Inhibitor ALS-L1023 from Melissa officinalis. PLoS ONE 10(11): e0141612.
Kim HT, Kim SJ, Sohn YI, Paik SS, Caplette R, Simonutti M, Moon K, Lee EJ, Min KW, Kim MJ, Lee DG, Simeone A, Lamonerie T, Furukawa T, Choi JS, Kweon HS, Picaud S, Kim IB, Shong M, Kim JW. (2015) Mitochondrial Protection by Exogenous Otx2 in Mouse Retinal Neurons. Cell Rep 13: 990 – 1002.
Lee HJ, Yoon JH, Ahn JS, Jo EH, Kim MY, Lee YC, Kim JW, Ann EJ, Park HS. (2015) Fe65 negatively regulates Jagged1 signaling by decreasing Jagged1 protein stability through the E3 ligase Neuralized-like 1. Biochim Biophys Acta 1853: 2918 - 2928.
2014
Kim NS, Min KW, Kang KH, Lee EJ, Kim HT, Moon K, Choi J, Le D, Lee SH, Kim JW. (2014) Regulation of retinal axon growth by secreted Vax1 homeodomain protein. eLife 3: e02671.
Bernard C*, Kim HT*, Torero Ibad R*, Lee EJ, Simonutti M, Picaud S, Acampora D, Simeone A, Di Nardo AA, Prochiantz A, Moya KL**, Kim JW**. (2014) Graded Otx2 activities demonstrate dose-sensitive eye and retina phenotypes. Hum Mol Genet 23: 1742 - 1753.
2013
Kim HJ, Woo HM, Ryu J, Bok J, Kim JW, Choi SB, Park MH, Park HY, Koo SK. (2013) Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development. PLoS One. 2013;8(2): e55609.
2012
Kim HT, Kim JW. (2012) Compartmentalization of vertebrate optic neuroephithelium: external cues and transcription factors. Mol Cells 33, 317 – 324 (review).
Jo HS, Kang KH, Joe CO, Kim JW. (2012) Pten coordinates retinal neurogenesis by regulating Notch signalling. EMBO J. 31: 817 - 828.
2011
Kwak SS, Suk J, Choi JH, Yang S, Kim JW, Sohn S, Chung JH, Hong YH, Lee DH, Ahn JK, Min H, Fu YM, Meadows GG, Joe CO. (2011) Autophagy induction by tetrahydrobiopterin deficiency. Autophagy 7: 1323 - 1334.
Lee EJ, Kim N, Kang KH, Kim JW. (2011) Phosphorylation/inactivation of PTEN by Akt-independent PI3K signaling in retinal pigment epithelium. Biochem Biophys Res Commun 414: 384 - 389.
2009
Lee JH, Suk J, Park J, Kim SB, Kwak SS, Kim JW, Lee CH, Byun B, Ahn JK, Joe CO. (2009) Notch signal activates hypoxia pathway through HES1-dependent SRC/signal transducers and activators of transcription 3 pathway. Mol Cancer Res 7: 1663 - 1671.
Kang KH, Lemke, G, Kim JW. (2009) The PI3K-PTEN tug-of-war, oxidative stress and retinal degeneration. Trends Mol Med 15: 191 – 198 (review).
2008
Kim JW**, Kang KH, Burrola P, Mak TW, Lemke G** (2008) Retinal degeneration triggered by inactivation of PTEN in the retinal pigment epithelium. Genes Dev 22: 3147 - 3157.
2006
Kim JW, Lemke G. (2006) Hedgehog-regulated localization of Vax2 controls eye development. Genes Dev 20: 2833 - 2847 (cover issue).