There are large variety of organic compounds that can serve as the indicator of air pollution in the environment such as polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), Polycyclic aromatic hydrocarbon (PAHs), Polychlorinated Naphthalene (PCN). Due to their persistent characteristics, they are also a threat to human health.
Micro-plastics are gaining much more attention in the recent years. With the size of millimeter to micron, they can penetrate into and accumulate in human and animal's body. However, the high volume sampling and analysis methodology of ambient air micro-plastics have yet developed, our team focuses on how to effectively collect and separate large amount of micro-plastics. Purified micro-plastics will go through chemical analysis to study their characteristics and possible sources.
Historically, air quality index (AQI) has been used as warning system to advise human’s activities. However, AQI calculation solely depends on air pollution concentration including particulate matter, however each particulate matter as different components based on their sources. Biological researches suggested that oxidative stress might be better in predicting acute human impact.
We proposed the development of an oxidative potential monitoring system for aerosols. The result of the monitoring system will be compared with cellular experiment for validation. At the same time, an epidemiological research is conducted to identify how different levels of oxidative stress influenced health outcome.
Ubiquitous in daily life, the hazard of PFAS lies not in acute toxicity, but in chronic, low-dose bioaccumulation through multiple exposure pathways. By leveraging molecular mimicry, PFAS disrupt cellular receptors and signaling pathways, leading to multi-systemic health impairments across metabolic, immune, and reproductive systems, as well as carcinogenicity. This underlying mechanism has driven increasingly stringent regulatory standards—such as drinking water thresholds—by global academia, the U.S. EPA, and the European Union in recent years.