Publications

Selected publications

1. LG Jang*, JW Huh*, et al. Mouth-to-gut microbial transmission signatures enable robust, non-invasive diagnosis of gastrointestinal cancers. Cell Host & Microbe. 2026 Aug 20; doi.org/10.1016/j.chom.2026.07.007 (*Co-first; IF = 23.2, 98.5% in Microbiology; 한빛사 논문)

   • • This study performed paired oral–fecal microbiome analysis in healthy individuals and patients with gastrointestinal (GI) cancers, complemented by extensive meta-analysis to chracterize generalizable oral-to-gut microbial  dynamics. 

     • GI cancer patients showed impaired decoupling between the oral and gut microbiomes, and ectopic transmission of oral bacteria was demonstrated to be a robust predictor of the GI cancers.

2. JW Huh, et al Enterotypical Prevotella and three novel bacterial biomarkers in preoperative stool predict the clinical outcome of colorectal cancer. Microbiome. 2022 Nov 28;10(1):203. doi: 10.1186/s40168-022-01388-8. (IF = 15.5, 96.5% in Microbiology; 한빛사 논문) 

• This paper revealed that the gut microbiota can predict the medical outcomes of colorectal cancer patients

• Fiber-digesting genus of Prevotella may improve the health of CRC patients

3. KH Kim*, Y Chung*, JW Huh*, et al. Gut microbiota of the young ameliorates physical fitness of the aged in mice. Microbiome. 2022 Dec 26;10(1):238. doi: 10.1186/s40168-022-01386-w. (*Co-first; IF = 15.5, 96.5% in Microbiology; 한빛사 논문) 

• This paper demonstrated that the gut microbiome of the young donor can rejuvenate the aged phenotype of skin and muscle in mice

• This also identified a host gene that is regulated by the 'young' microbiome and affects the skin phenotype

4. JW Huh$, et al. Charge-dependent localization of Toll-like receptor 5 at the plasma membrane. Mol Cells. 2025 Nov;48(11):100275. doi: 10.1016/j.mocell.2025.100275. Epub 2025 Sep 5. ($Correspondence; IF = 8.2, 88.3% in Molecular Biology)

5. JW Huh and TY Roh. Opportunistic detection of Fusobacterium nucleatum as a marker for the early gut microbial dysbiosis. BMC Microbiol. 2020 Jul 13;20(1):208. doi: 10.1186/s12866-020-01887-4.  (IF = 5.4, 78.1% in Microbiology) 

• This paper suggested a novel method for identifying 'dysbiosis' in the early phase from a longitudinal perspective. (cited# 87)

6. JW Huh*, T Shibata*, et al. UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5. Proc Natl Acad Sci U S A. 2014 May 13;111(19):7072-7. doi: 10.1073/pnas.1322838111. Epub 2014 Apr 28. (*Co-first; IF = 9.5, 90.4% in Multidisciplinary Science; 한빛사 논문) 

Others

1. J Kim, JW Huh, et al. Acidic amino acid residues in the juxtamembrane region of the nucleotide-sensing TLRs are important for UNC93B1 binding and signaling. J Immunol. 2013 May 15;190(10):5287-95. doi: 10.4049/jimmunol.1202767. Epub 2013 Apr 12. (IF = 5.4, 83.7% in Immunology)

2. HS Song, S Park, JW Huh, et al. N-glycosylation of UNC93B1 at a Specific Asparagine Residue Is Required for TLR9 Signaling. Front Immunol. 2022 Jul 7;13:875083. doi: 10.3389/fimmu.2022.875083. (IF = 7.3, 78.6% in Immunology) 

3. W Kang, A Park, JW Huh, et al.G You, DJ Jung, M Song, HK Lee, YM Kim. Flagellin-Stimulated Production of Interferon-β Promotes Anti-Flagellin IgG2c and IgA Responses. Mol Cells. 2020 Mar 31;43(3):251-263. doi: 10.14348/molcells.2020.2300. (IF = 8.2, 88.3% in Molecular Biology) 

4. S Kim, H Nam, E Lee, JW Huh, et al. Ion concentration polarization-based multifunctional microfluidic device for analysis of intracellular components. Sens. Actuator B-Chem. 2022. Nov 371(15). doi: 10.1016/j.snb.2022.132576 (IF = 7.7, 96.0% in Analytical Chemistry)

5. C Park, SA Lee, JH Hong, Y Suh, SJ Park, BK Suh, Y Woo, J Choi, JW Huh, et al. Disrupted-in-schizophrenia 1 (DISC1) and Syntaphilin collaborate to modulate axonal mitochondrial anchoring. Mol Brain. 2016 Jul 2;9(1):69. doi: 10.1186/s13041-016-0250-2. (IF = 2.9)