Huh JW, Kim MJ, Kim J, Lee HG, Ryoo SB, Ku JL, Jeong SY, Park KJ, Kim D, Kim JF, Park JW. Enterotypical Prevotella and three novel bacterial biomarkers in preoperative stool predict the clinical outcome of colorectal cancer. Microbiome. 2022 Nov 28;10(1):203. doi: 10.1186/s40168-022-01388-8. (JCF 2022 IF = 15.5, 95.2% in Microbiology)
This paper revealed that the gut microbiota can predict the medical outcomes of colorectal cancer patients.
Fiber-digesting genus of Prevotella may improve the health of CRC patients
Kim KH*, Chung Y*, Huh JW*, Park DJ, Cho Y, Oh Y, Jeong H, Yoon J, Kang JH, Shin HS, Kim HC, Kwon SK, Seo KY, Oh SH, Seong JK, Ha SJ, Nam KT, Kim JF. Gut microbiota of the young ameliorates physical fitness of the aged in mice. Microbiome. 2022 Dec 26;10(1):238. doi: 10.1186/s40168-022-01386-w. (*Co-first authors) (JCF 2022 IF = 15.5, 95.2% in Microbiology)
This paper demonstrated that the gut microbiome of the young donor can rejuvenate the aged phenotype of skin and muscle in mice
This also identified a host gene that is regulated by the 'young' microbiome and affects the skin phenotype.
Huh JW, Roh TY. Opportunistic detection of Fusobacterium nucleatum as a marker for the early gut microbial dysbiosis. BMC Microbiol. 2020 Jul 13;20(1):208. doi: 10.1186/s12866-020-01887-4. (JCF 2020 IF = 3.6)
This paper suggested a novel method for identifying 'dysbiosis' in the early phase from a longitudinal perspective.
Song HS, Park S, Huh JW, Lee YR, Jung DJ, Yang C, Kim SH, Kim HM, Kim YM. N-glycosylation of UNC93B1 at a Specific Asparagine Residue Is Required for TLR9 Signaling. Front Immunol. 2022 Jul 7;13:875083. doi: 10.3389/fimmu.2022.875083. (JCF 2022 IF = 7.3)
Kang W, Park A, Huh JW, You G, Jung DJ, Song M, Lee HK, Kim YM. Flagellin-Stimulated Production of Interferon-β Promotes Anti-Flagellin IgG2c and IgA Responses. Mol Cells. 2020 Mar 31;43(3):251-263. doi: 10.14348/molcells.2020.2300. (JCF 2020 IF = 5.0)
Huh JW*, Shibata T*, Hwang M, Kwon EH, Jang MS, Fukui R, Kanno A, Jung DJ, Jang MH, Miyake K, Kim YM. UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5. Proc Natl Acad Sci U S A. 2014 May 13;111(19):7072-7. doi: 10.1073/pnas.1322838111. Epub 2014 Apr 28. (*Co-first authors) (JCF 2014 IF = 9.7, 93.9% in Multidisciplinary Science)
Kim J, Huh J, Hwang M, Kwon EH, Jung DJ, Brinkmann MM, Jang MH, Ploegh HL, Kim YM. Acidic amino acid residues in the juxtamembrane region of the nucleotide-sensing TLRs are important for UNC93B1 binding and signaling. J Immunol. 2013 May 15;190(10):5287-95. doi: 10.4049/jimmunol.1202767. Epub 2013 Apr 12. (JCF 2013 IF = 5.4, 83.7% in Immunology)