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Select Paper: ChainSpace: Sequence-Aware Design for Machine Learning-Driven Polymer Engineering
Papers
Papers
2022 – Present
2022 – Present
Materials informatics & gene delivery · 11 publications
JOURNAL COVER ART · VOL. 227
2026 · MACRO. CHEM. PHYS.
Polymeric Delivery of DNA-Encoded Biologics
Ting, J. M.; Dykeman-Bermingham, P.; Cairns, C. E.; Petersen, S. R.; Snell, N. J.; Miskin, R. P.; Fisher, J. D.; Murthy, S.; Kevlahan, S. H.; Guzman, G.; Neenan, T. X.
2025 · CHEMRXIV
ChainSpace: Sequence-Aware Design for Machine Learning-Driven Polymer Engineering
Guzman, G.*; Ting, J. M.*; Murthy, S.; Neenan, Thomas X.; Kevlahan, S. H.
DOI: 10.26434/chemrxiv-2025-cs3gj
2025 · BIORXIV
In Vivo Production of a Protein via the Delivery of Plasmid DNA by a Computationally Designed Polymer Nanoparticles (PNP)
Fisher, J.; Petersen, S.; Heynes, O.; Patil, S.; Tamayo-Mendoza, T.; Oviedo, F.; Guzman, G.; Van Reet, J.; Ting, J. M.; Kevlahan, S.; Neenan, Thomas X.; Murthy, S. K.
DOI: 10.1101/2025.02.14.638338
JOURNAL COVER ART · VOL. 15
Predictive Design of Multimonomeric Polyelectrolytes Enables Lung-Specific Gene Delivery
Ting, J. M.; Fisher, J. D.; Conyers, T.; Patil, S.; Tamayo, T.; Oviedo, F.; Murthy, S. K.
Polym. Chem., 2024
2024 · POLYM. CHEM.
Predictive Design of Multimonomeric Polyelectrolytes Enables Lung-Specific Gene Delivery
Ting, J. M.; Fisher, J. D.; Conyers, T.; Patil, S.; Tamayo, T.; Oviedo, F.; Murthy, S. K.
DOI: 10.1039/D4PY00196F
2024 · ACS POLYM. AU
Finding Professional Growth and Fulfillment for Early-Career Polymer Scientists and Engineers in Industry
Ting, J. M.; Sims, M. B.
DOI: 10.1021/acspolymersau.4c00039
2023 · CHEM. COMMUN.
Frontiers in Nonviral Delivery of Small Molecule and Genetic Drugs, Driven by Polymer Chemistry and Machine Learning for Materials Informatics
Ting, J. M.; Tamayo, T.; Petersen, S. R.; Van Reet, J.; Ahmed, U. A.; Snell, N. J.; Fisher, J. D.; Stern, M.; Oviedo, F.
(2023 Emerging Investigators) 10.1039/D4CC90057J
DOI: 10.1039/D3CC04705A
ChemComm Milestones-First Independent Articles
2023 · MACROMOLECULES
Effect of Charged Block Length Mismatch in Double Diblock Polyelectrolyte Complex Micelle Cores
Stevens, K. C.; Marras, A. E.; Campagna, T.; Ting, J. M.; Tirrell, M. V.
ACS AuthorChoice - Open Access
DOI: 10.1021/acs.macromol.3c00555
JOURNAL COVER ART · VOL. 17, ISS. 23
Targeted polymersome delivery of a stapled peptide for drugging the p53:BCL-2-family axis in diffuse large B-cell lymphoma
Schnorenberg, M. R.; Hawley, K. M.; Thomas-Toth, A. T.; Watkins, E. A.; Tian, Y.; Ting, J. M.; Leak, L. B.; Kucera, I. M.; Raczy, M. M.; Kung, A. L.; Hubbell, J. A.; Tirrell, M. V.; LaBelle, J. L.
ACS Nano, 2023
2023 · ACS NANO.
Targeted polymersome delivery of a stapled peptide for drugging the p53:BCL-2-family axis in diffuse large B-cell lymphoma
Schnorenberg, M. R.; Hawley, K. M.; Thomas-Toth, A. T.; Watkins, E. A.; Tian, Y.; Ting, J. M.; Leak, L. B.; Kucera, I. M.; Raczy, M. M.; Kung, A. L.; Hubbell, J. A.; Tirrell, M. V.; LaBelle, J. L.
ACS AuthorChoice - Open Access
2022 · MOL. SYST. DES. ENG.
In Silico Active Learning for Small Molecule Properties
Schneider, L.; Schwarting, M.; Mysona, J.; Liang, H.; Han, M.; Rauscher, P. M.; Ting, J. M.; Venkatram, S.; Ross, R. B.; Schmidt, K. J.; Blaiszik, B.; Foster, I.; de Pablo, J. J.
DOI: 10.1039/D2ME00137C
2022 · PURE APPL. CHEM.
Launching a Materials Informatics Initiative for Industrial Applications in Materials Science, Chemistry, and Engineering
Ting, J. M.; Lipscomb, C. E.
Editorial on Special Issue on Cheminformatics: Data and Standards
2017 – 2021
2017 – 2021
Polyelectrolyte complexes & self-assembly · 27 publications
2021 · J. PHYS. CHEM. B
Advances in the Structural Design of Polyelectrolyte Complex Micelles
Marras, A. E.; Ting, J. M.; Stevens, K. C.; Tirrell, M. V.
ACS AuthorChoice - Open Access
2022 · J. ELECTROCHEM. SOC..
Translocation Behaviors of Synthetic Polyelectrolytes through Alpha-Hemolysin (α-HL) and Mycobacterium smegmatis Porin A (MspA) Nanopores
Wang, X.; Stevens, K. C.; Ting, J. M.; Marras, A. E.; Rezvan, G.; Wei, X.; Qazvini, N. T.; Tirrell, M. V.; Liu, C.
2021 · MOL. SYST. DES. ENG.
Complex Coacervation of Statistical Polyelectrolytes: Role of Monomer Sequences and Formation of Inhomogeneous Coacervates
Yu, B.; Rumyantsev, A. M.; Jackson, N. E.; Liang, H.; Ting, J. M.; Meng, S.; Tirrell, M. V.; de Pablo, J. J.
DOI: 10.1039/D1ME00076D
2020 · NAT. COMM.
Impact of Wet-Dry Cycling on the Phase Behavior and Compartmentalization Properties of Complex Coacervates
Fares, H. M.; Marras, A. E.*; Ting, J. M.*; Tirrell, M. V.; Keating, C. D.
(Open Access).
DOI: 10.1038/s41467-020-19184-z
ChemRxiv 2020 (Open Access) DOI: 10.26434/chemrxiv.12278318.v1
Nat. Res. Chem. Community · PME Website · PSU Website · Phys Org · ScienMag · ScienceDaily · EurekaAlert! · Condensates
2021 · METHODS ENZYMOL.
SAXS Methods for Investigating Macromolecular and Self-Assembled Polyelectrolyte Complexes
Marciel, A. B.; Srivastava, S.; Ting, J. M.; Tirrell, M. V.
(Open Access).
DOI: 10.1016/bs.mie.2020.09.013
2021 · J. CHEM ED.
Safety Moments in Chemical Safety Education
Ting, J. M.
DOI: 10.1021/acs.jchemed.0c00220
Wiki: Safety Culture · UMN Chemistry
JOURNAL COVER ART · VOL. 53, ISS. 18
Solid-to-Liquid Phase Transition in Polyelectrolyte Complexes
Meng, S.; Ting, J. M.; Wu, H.; Tirrell, M. V.
Macromolecules, 2020
2020 · MACROMOLECULES
Solid-to-Liquid Phase Transition in Polyelectrolyte Complexes
Meng, S.; Ting, J. M.; Wu, H.; Tirrell, M. V.
DOI: 10.1021/acs.macromol.0c00930
ChemRxiv 2020 (Open Access) DOI: 10.26434/chemrxiv.12121086.v1
2020 · COLLOID POLYM. SCI.
Effect of Mixed Solvents on Polyelectrolyte Complexes with Salt
Meng, S.; Liu, Y; Yeo, J.; Ting, J. M.; Tirrell, M. V.
(Open Access)
DOI: 10.1007/s00396-020-04637-0
2020 · MOLECULES
Comparing Zwitterionic and PEG Exteriors of Polyelectrolyte Complex Micelles
Ting, J. M.*; Marras, A. E.*; Mitchell, J. D.; Campagna, T.; Tirrell, M. V.
(Open Access) DOI: 10.3390/molecules25112553
ChemRxiv 2020 (Open Access) DOI: 10.26434/chemrxiv.12237020
Materials Data Facility 2020 (Open Access) DOI: 10.18126/n4un-6usf
Molecules 7/2020 Featured Paper
2019 · CHEMRXIV
Patterning Polyelectrolyte Complexes with Alternating Monomer Sequence Distributions
Herzog-Arbeitman, A.*; Ting, J. M.*; Meng, S.; Wu, H.; Tirrell, M. V.
ChemRxiv 2019 (Open Access) DOI: 10.26434/chemrxiv.11320439.v1
2020 · MACROMOLECULES
Effects of Non-Electrostatic Intermolecular Interactions on the Phase Behavior of pH-Sensitive Polyelectrolyte Complexes
Li, L.; Srivastava, S.; Meng, S.; Ting, J. M.; Tirrell, M. V.
DOI: 10.1021/acs.macromol.0c00999
ChemRxiv 2020 (Open Access) DOI: 10.26434/chemrxiv.12213509
2020 · ACS CHEM. HEALTH SAF.
Lessons Learned from the Creation and Development of a Researcher-Led Safety Organization at The University of Chicago
Zinn, S. R.; Slaw, B.; Lettow, J. R.; Menssen, R. J.; Wright, J. H.; Mormann, K.; Ting, J. M.
2020 · ACS MACRO LETT.
Spatiotemporal Formation and Growth Kinetics of Polyelectrolyte Complex Micelles with Millisecond Resolution
Wu, H.*; Ting, J. M.*; Meng, S.; Yu, B.; Jackson, N. E.; de Pablo, J. J.; Tirrell, M. V.
DOI: 10.1021/acsmacrolett.0c00543
ChemRxiv 2019 (Open Access) DOI: 10.26434/chemrxiv.9876395
2020 · MACROMOLECULES
Mechanism of Dissociation Kinetics in Polyelectrolyte Complex Micelles
Wu, H.; Ting, J. M.; Tirrell, M. V.
DOI: 10.1021/acs.macromol.9b01814
ChemRxiv 2019 (Open Access) DOI: 10.26434/chemrxiv.9736385.v1
C&EN CAREERS FEATURE · VOL. 97, ISS. 35
Why Postdocs Should Spend Time Building Bridges
Chem. Eng. News, 2019
Ting, J. M.
JOURNAL COVER ART · VOL. 8, ISS. 7
Interparticle Interactions in Dilute Solutions of Polyelectrolyte Complex Micelles
Wu, H.*; Ting, J. M.*; Weiss, T. M.; Tirrell, M. V.
ACS Macro Lett., 2019
2019 · J. CHEM ED.
Integrating Systems Thinking Into Teaching Emerging Technologies
Fowler, W.*; Ting, J. M.*; Meng, S.; Li, L.; Tirrell, M. V.
DOI: 10.1021/acs.jchemed.9b00280
2019 · ACS MACRO LETT.
Controlling Complex Coacervation via Random Polyelectrolyte Sequences
Rumyantsev, A. M.; Jackson, N. E.; Yu, B.; Ting, J. M.; Chen, W.; Tirrell, M. V.; de Pablo, J. J.
DOI: 10.1021/acsmacrolett.9b00494
2019 · ACS MACRO LETT.
Interparticle Interactions in Dilute Solutions of Polyelectrolyte Complex Micelles
Wu, H.; Ting, J. M.; Weiss, T. M.; Tirrell, M. V.
DOI: 10.1021/acsmacrolett.9b00226
ChemRxiv 2019 (Open Access) DOI: 10.26434/chemrxiv.7905275.v1
2019 · POLYM. CHEM.
Tuning PNIPAm Self-Assembly and Thermoresponse: Roles of Hydrophobic End-Groups and Hydrophilic Comonomer
Ohnsorg, M.; Ting, J. M.; Jones, S. D.; Jung, S.; Bates, F. S.; Reineke, T. M.
DOI: 10.1039/C9PY00180H
2019 · POLYMERS
Polyelectrolyte Complexation of Oligonucleotides by Charged Hydrophobic –Neutral Hydrophilic Block Copolymers
Marras, A. E.; Vieregg, J. R.; Ting, J. M.; Rubien, J. D.; Tirrell, M. V.
(Open Access)
ChemRxiv 2018 (Open Access) DOI: 10.26434/chemrxiv.7456322.v1
Materials Data Facility 2018 (Open Access) DOI: 10.18126/M2QW8R
2018 · J. CHEM. PHYS.
Non-Equilibrium Phenomena and Kinetic Pathways in Self-Assembled Polyelectrolyte Complexes
Wu, H.; Ting, J. M.; Werba, O.; Meng, S.; Tirrell, M. V.
DOI: 10.1063/1.5039621
2018 · ACS MACRO LETT.
Synthesis and Assembly of Designer Styrenic Diblock Polyelectrolytes
Ting, J. M.; Wu, H.; Herzog-Arbeitman, A.; Srivastava, S.; Tirrell, M. V.
DOI: 10.1021/acsmacrolett.8b00346
ChemRxiv 2018 (Open Access) DOI: 10.26434/chemrxiv.6223760.v1
JOURNAL COVER ART · VOL. 29, ISS. 4
Advances in Polymer Design for Enhancing Oral Drug Solubility and Delivery
Ting, J. M.; Porter III, W. W.; Mecca, J. M.; Bates, F. S.; Reineke, T. M.
Bioconjugate Chem., 2018
2019 · ACS OMEGA
Evaluating Large-Scale STEM Outreach Efficacy with a Consistent Theme: Thermodynamics for Elementary School Students
DeWilde, J. F.; Rangnekar, E.*; Ting, J. M.*; Franek, J. E.; Bates, F. S.; Hillmyer, M. A.; Blank, D. A.
(Open Access)
ChemRxiv 2018 (Open Access) DOI: 10.26434/chemrxiv.7462067.v1
UMN Chemistry News · Wiki: Science Outreach
2018 · ACS MACRO LETT.
Open-to-Air RAFT Polymerization in Complex Solvents: From Whisky to Fermentation Broth
Schneiderman, D. K.; Ting, J. M.; Purchel, A. A.; Miranda, R. Jr.; Tirrell, M. V.; Reineke, T. M.; Rowan, S. J.
DOI: 10.1021/acsmacrolett.8b00069
2018 · BIOCONJUGATE CHEM.
Advances in Polymer Design for Enhancing Oral Drug Solubility and Delivery
Ting, J. M.; Porter III, W. W.; Mecca, J. M.; Bates, F. S.; Reineke, T. M.
DOI: 10.1021/acs.bioconjchem.7b00646
PhysOrg · Technology.org · Wiki: Spray Drying · OnDrugDelivery
2017 · CHEM. SOC. REV.
Molecular Engineering Solutions for Therapeutic Peptide Delivery
Acar, H.; Ting, J. M.; Srivastava, S.; LaBelle, J. L.; Tirrell, M. V.
DOI: 10.1039/C7CS00536A
IME News · Wiki: Molecular Engineering
2017 · J. CHEM. EDUC.
Polymer Day: Outreach Experiments for High School Students
Ting, J. M.; Ricarte, R. G.*; Schneiderman, D. K.*; Jiang, Y.; Saba, S. A.; Hillymer, M. A.; Bates, F. S.; Reineke, T. M.; Macosko, C. W.; Lodge, T. P.
DOI: 10.1021/acs.jchemed.6b00767
ACS AuthorChoice - Open Access
Chem Ed XChange · Chem Ed XChange 2 · DiversifyChem · Wiki: Science Outreach
2017 · MACROMOLECULES
Direct observation of nanostructures during aqueous dissolution of polymer/drug particles
Ricarte, R. G.; Li, Z.; Johnson, L.; Ting, J. M.; Reineke, T. M.; Bates, F. S.; Hillmyer, M. A.; Lodge, T. P.
DOI: 10.1021/acs.macromol.7b00372
2013 – 2016
2013 – 2016
Polymer excipients for oral drug delivery · 4 publications
2016 · ACS CENT. SCI.
High–throughput Excipient Discovery Enables Oral Delivery of Poorly Soluble Pharmaceuticals
Ting, J. M.; Tale, S.; Purchel, A. A.; Jones, S. D.; Widanapathirana, L.; Tolstyka, Z. P.; Li, G.; Guillaudeu, S. J.; Bates, F. S.; Reineke, T. M.
DOI: 10.1021/acscentsci.6b00268
ACS AuthorChoice - Open Access
Patent · Minnesota Daily · EurekAlert! · Tablets & Capsules · Science Daily · PhysOrg · AIChE YP Blog · UMN College of Science & Engineering News
2015 · ACS BIOMAT. SCI. ENG.
Deconstructing HPMCAS: Excipient Design to Tailor Polymer–drug Interactions for Oral Drug Delivery
Ting, J. M.; Navale, T. S.; Jones, S. D.; Bates, F. S.; Reineke, T. M.
DOI: 10.1021/acsbiomaterials.5b00234
ACS Editors’ Choice Award - Open Access
1st ACS Editors' Choice distinction in this journal · AIChE Young Professionals Graduate Student Research Spotlight · UMN CEMS News · UMN Chem News
2014 · MACROMOLECULES
Design of Tunable Multicomponent Polymers as Modular Vehicles to Deliver Highly Lipophilic Drugs
Ting, J. M.*; Navale, T. S.*; Bates, F. S.; Reineke, T. M.
DOI: 10.1021/ma501839s
2013 · ACS MACRO LETT.
Precise Compositional Control and Systematic Preparation of Multimonomeric Statistical Copolymers
Ting, J. M.*; Navale, T. S.*; Bates, F. S.; Reineke, T. M.
DOI: 10.1021/mz4003112
Patents & Other Cover Arts
Patents & Other Cover Arts
PATENT APPLICATION
Pressure sensitive adhesive compositions comprising polymerized amide monomers, articles, and methods
Application No. PA100265US01.
PATENT APPLICATION
Copolymers as Excipients for Effective Solubilization of Poorly Water-Soluble Substances from Solid Mixtures
Reineke, T. M.; Tale, S.; Bates, F. S.; Ting, J. M.; Widanapathirana, L.; Guillaudeu, S.; Li, G.
Application No. 62/127,874, filed March 2015.
PATENT APPLICATION
Sugar containing, amphiphilic copolymers
Navale, T. S.; Ting, J. M.; Bates, F. S.; Reineke, T. M.
Application No. 61/819,923, filed May 2013.
PATENT APPLICATION
Sugar free, random copolymers made from at least three monomers
Navale, T. S.; Ting, J. M.; Bates, F. S.; Reineke, T. M.
Application No. 61/819,928, filed May 2013.
COVER ART & REPORT DESIGN
Frontiers in Polymer Science and Engineering: Report of a 2016 NSF Workshop
Chaired by Frank S. Bates; Steering committee included Pat Brant, Geoffrey Coates, Jane Lipson, Chinedum Osuji, Juan de Pablo, Stuart J. Rowan, Rachel Segalman, and Karen I. Winey.
JOURNAL COVER ART · VOL. 50, ISS. 10
50th Anniversary Perspective: There Is a Great Future in Sustainable Polymers
Schneiderman, D. K.; Hillmyer, M. A.
Macromolecules, 2017
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