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46. One-step synthesis of 2-arylindoles from indolines via Pd-catalyzed oxidative dehydrogenation and C2-selective arylation
Y. S. Yang, J. Yoo, J. Jeon, J. H. Bak, J. W. Shin, H. J. Won, H. S. Hwang, J. H. Kim, J. Sim*, N. J. Kim*
RSC Advances 2025, 15, 28131-28135 Link
45. Natural products targeting the metabolism of amino acids: from discovery to synthetic development
H. S. Kim, A. H. E. Hassan, K. Moon, J. Sim*
Natural Product Reports 2025 Link
44. Discovery of Cyclopentane-Based Phospholipids as Miltefosine Analogs with Superior Potency and Enhanced Selectivity Against Naegleria fowleri
A. H. E. Hassan, H. G. Le, T. C. Vo, M. Kim, J. H. No, M. H. Aboutaleb, J. Sim, B. K. Na*, Y. S. Lee*
Pharmaceuticals 2025, 18, 984. Link
43. Photoinduced Site-Selective Alkylation Enabling Synthesis of C‑3 Alkylated Quinoxalinone on DNA
K. S. Kim▽, J. Ra▽, H. B. Madala, E. Jang, S. Kang, M. Yoo, T. M. B. Thinh, K. Moon, J. Sim*
Organic Letters 2025, 27, 4777-4781. Link
42. Design, synthesis and evaluation of acetylcholine antitumor lipid hybrids led to identification of a potential anticancer agent disrupting the CDK4/6 Rb pathway in lung cancer
A. H. E. Hassan, E. S. Bae, Y. Jeong, C. W. Ock, S. M. El-Sayed, M. Kim, M. F. Radwan, T. S. Ibrahim, J.-Y. Cho, B. Y. Park, J. Sim, S. K. Lee*, Y. S. Lee*
RSC Medicinal Chemistry 2025, Advance Article Link
41. Photoredox Catalyzed Oxidative C-H Alkylation of Glycine Derivatives with 4-alkyl-1,4-dihydropyridines
H. B. Madala#, E. Jang#, H. S. Jang, S. K. Kim, J. Sim*
Synthesis 2024, 56, 2339-2346. Link
40. Synthesis of 2,3-Benzotropones via Palladium(II)-Catalyzed Aerobic Dehydrogenation from 1‑Benzosuberones and Sequential Diels−Alder Reaction to Yield Benzobicyclo[3.2.2]nonenones
H.-S. Y, J.-W. S, Y. H. J, Y.-S. Y, S. H. S, H.-J. W, S. L. K, J. Sim*, N.-J. K*
The Journal of Organic Chemistry 2024, 89, 3102-3110. Link
39. Role of microsomal metabolism in bromfenac-induced cytotoxicity
J. S. Jeon , H. Kim, S. Jo, J. Sim**, S. K. Kim*
Chemico-Biological Interactions 2024, 391, 110903. Link
38. Chemical Glycosylation with p‑Methoxyphenyl (PMP) Glycosides via Oxidative Activation
H. S. Kim# , E. Jang#, H. I. Kim, H. B. Madala, J.-Y. Lee, S. K. Kim*, J. Sim*
Organic Letters 2023, 25, 3471-3475. Link
37. Enhancement of the therapeutic efficacy of the MAP regimen using thiamine pyrophosphate-decorated albumin nanoclusters in osteosarcoma treatment
S.-Y. Yoo, Y.-H. Mun, N.-W. Kang, J. M. Koo, D. H. Lee, J. H. Yoo, S. M. Lee, S. Koh, J. C. Park, T. Kim, E. K. Shin, H. S. Lee, J. Sim, K. W. Kang, S. K. Kim, C.-W. Cho, M. G. Kim*, D.-D. Kim*, J.-Y. Lee*
Bioengineering & Translational Medicine 2022, e10472. Link
35. Radical-Mediated C-H Alkylation of Glycine Derivatives: A Straightforward Strategy for Diverse α-Unnatural Amino Acids
H. B. Madala, J. Sim*
European Journal of Organic Chemistry 2022, e202200859. Link
34. Ligand-Controlled Regiodivergent Direct Arylation of Indoles via Oxidative Boron Heck Reaction
Y. Yang, S. Lee, S. H. Son, H. Yoo, Y. H. Jang, J. Shin, H. Won, J. Sim* , N. Kim *
Organic Chemistry Frontiers 2022, 9, 5906-5911. Link
33. Photoredox-Catalyzed Oxidative Radical–Polar Crossover Enables the Alkylfluorination of Olefins
E. Jang, H. I. Kim, H. S. Jang, J. Sim*,
The Journal of Organic Chemistry 2022, 87, 2640–2650. Link
32. Total Syntheses of Pladienolide-Derived Spliceosome Modulators
J. Sim*, E. Jang, H. J. Kim, H. Jeon *
Molecules 2021, 26, 5938-5962. Link
31. Evaluation of Anti-Melanogenesis Activity of Enriched Pueraria lobata Stem Extracts and Characterization of Its Phytochemical Components Using HPLC–PDA–ESI–MS/MS
D. Gao , J. H. Kim, C. T. Kim, W. S. Jeong, H. M. Kim, J. Sim *, J. S. Kang *
International Journal of Molecular Sciences 2021, 22, 8105-8115. Link
30. Effect of citric acid and heat treatment on the content of less-polar ginsenosides in flower buds of Panax ginseng
D. Gao, J. H. Kim, L. B. Vinh, E. Y. Seo, S. Y. Yang , C. W. Cho, Y. H. Kim, K. T. Kim, J. Sim*, J. S. Kang*
Preparative Biochemistry & Biotechnology 2021, 144-153. Link
29. A Review of the Pharmacological Activities and Recent Synthetic Advances of γ-Butyrolactones Recent advances in development of hetero-bivalent kinase inhibitors
J. Hur, J. Jang *, J. Sim *
International Journal of Molecular Sciences 2021, 22, 2769-2816. Link
28. Recent advances in development of hetero-bivalent kinase inhibitors
S. Lee, J. Kim, J. Jo, J. W. Chang, J. Sim*, H. Yun*
European Journal of Medicinal Chemistry 2021, 216, 113318-113337. Link
27. Collective Syntheses of Guaiane Sesquiterpenes: Stereoselective Syntheses of (+)-Dysodensiol F, (+)-10β,14-Dihydroxy-allo-aromadendrane, and (−)-Dendroside C Aglycon
H. S. Kim, H. Park, J. Lim, C. Lim, T. Kim, S. Lee, J. S Hur, J. Sim*, H. J. Choi*, Y-G. Suh*
Journal of Organic Chemistry 2020, 85, 13779−13792. Link
26. Concise Synthesis of Catechin Metabolites 5-(3′,4′-Dihydroxyphenyl)-γ-valerolactones (DHPV) in Optically Pure Form and Their Stereochemical Effects on Skin Wrinkle-Reducing Activities
J. Hur, A-R. Kim, H. S. Kim, C. Lim, T. Kim, T.-A. Kim, J. Sim,* Y.-G. Suh*
Molecules 2020, 25, 1970-1979. Link
25. Multifunctional Building Blocks Compatible with Photoredox-Mediated Alkylation for DNA-Encoded Library Synthesis
S. O. Badir,§ J. Sim,§ K. Billings, A. Csakai, X. Zhang, W. Dong, G. A. Molander (§S.O.B. and J.S. contributed equally)
Organic Letters 2020. 22, 1046-1051. Link
24. Open-Air Alkylation Reactions in Photoredox-Catalyzed DNA Encoded Library Synthesis
P. Phelan, S. B. Lang, J. Sim, S. Berritt, A. Peat, K. Billings, L. Fan, G. A. Molander
Journal of The American Chemical Society 2019, 141, 3723-3732. Link
23. Synthesis of α-Fluoro-α-Amino Acid Derivatives via Photoredox-Catalyzed Carbofluorination
J. Sim, M. A. Campbell, G. A. Molander
ACS Catalysis 2019, 9, 1558-1563. Link
22. Indium(III) Triflate-Catalyzed Glycosylation via an Ambient Activation of Glycosyl Fluoride
J. Sim, S. Kim, J. Huh, C. Lim, H. Kim, Y.-G. Suh
Asian Journal of Organic Chemistry 2018, 8, 107-110. Link
21. Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for AngiogenesisRelated Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy
H. An, S. Lee, J. M. Lee, D. H. Jo, J. Kim, Y.-S. Jeong, M. J. Heo, C. S. Cho, H. Choi, J. H. Seo, S. Hwang, J. Lim, T. Kim, H. O. Jun, J. Sim, C. Lim, J. Hur, J. Ahn, H. S. Kim, S.-Y. Seo, Y. Na, S.-H. Kim, J. Lee, J. Lee, S.-J. Chung, Y.-M. Kim, K. Kim, S. G. Kim, J. H. Kim, Y.-G. Suh
Journal of Medicinal Chemistry 2018, 61, 9266-9286. Link
20. Conformationally-Inspired Total Syntheses of Ohmyungsamycins A and B and Structural Revision of Ohmyungsamycin B
J. Hur, J. Jang, J. Sim, W. S. Son, H.-C. Ahn, T. S. Kim, Y.-H. Shin, C. Lim, S. Lee, H. An, S.-H. Kim, D.-C. Oh, E.-K. Jo, J. Jang, J. Lee, Y.-G. Suh
Angewandte Chemie International Edition 2018, 57, 3123-3127. Link
19. Stereoselective Synthesis of 1,4,5-Tri-cis-guaiane Sesquiterpene: First Total Synthesis of (−)-Dendroside C Aglycon
J. Sim, H. Park, J. Lim, I. Yoon, C. Lim, H. An, H. Yun, H. J. Choi, Y.-G. Suh
Organic Letters 2018, 20, 586-589. Link
18. Asymmetric Total Synthesis of (+)-(3E)‑Pinnatifidenyne via Abnormally Regioselective Pd(0)-Catalyzed Endocyclization
H, S. Kim, T. Kim, J. Ahn, H. Yun, C. Lim, J. Jang, J. Sim, H. An, Y.-J. Surh, J. Lee, Y.-G. Suh
The Journal of Organic Chemistry 2018, 83, 1997-2005. Link
17. Total Synthesis of (+)-Brasilenyne via Concise Construction of Oxonane Framework Containing 1,3-cis,cis-Diene
C. Lim, J. Ahn, J. Sim, H. Yun, J. Hur, H. An, J. Jang, S. Lee, Y.-G. Suh
Chemical Communication 2018, 54, 467-470. Link
16. Practical and Sustainable Synthesis of Optically Pure Levocabastine, a H1 Receptor Antagonist
S. K. Kang, D. H. Nam, J. Ahn, J. Lee, J. Sim, J. Lee, Y.-G. Suh
Molecules 2017, 22, 1971-1980. Link
15. Nicrophorusamides A and B, Antibacterial Chlorinated Cyclic Peptides from a Gut Bacterium of the Carrion Beetle Nicrophorus concolor
Y.-H. Shin, S. Bae, J. Sim, J. Hur, S.-I. Jo, J. Shin, Y.-G. Suh, K.-B. Oh, D.-C. Oh
Journal of Natural Products 2017, 80, 2962-2968. Link
14. Practical and Efficient Synthesis of Gefitinib via Selective O-Alkylation: A Novel Concept for a Transient Protection Group
S. K. Kang, S. W. Lee, D. Woo, J. Sim, Y.-G. Suh
Synthetic Communication 2017, 47, 1990-1998. Link
13. Construction of the Azacyclic Core of Tabernaemontanine-Related Alkaloids via Tandem Reformatsky−Aza-Claisen Rearrangement
Y.-G. Suh, C. Lim, J. Sim, J. K. Lee, Y.-J. Surh, S.-M. Paek
The Journal of Organic Chemistry 2017, 82, 1464-1470. Link
12. A Highly Stereoselective and Efficient Synthesis of Enantiomerically Pure Sitagliptin
S. K. Kang, G. H. Cho, H. J. Leem, B. K. Soh, J. Sim, Y.-G. Suh
Tetrahedron: Asymmetry 2016, 28, 34-40. Link
10. Studies on the Aza-Claisen Rearrangement of 7 to 9-membered Vinylazacycles
S.-H. Kim, W.-I. Lee, S.-M. Kim, J.-K. Jung, J. Jang, J. Sim, J.-W. Jung, Y.-G. Suh
Heterocycles 2016, 92, 886-899. Link
09. Divergent Synthetic Route to New Cyclopenta[c]pyran Iridoids: Syntheses of Jatamanin A, F, G and J, Gastrolactone and Nepetalactone
J. Sim, I. Yoon, H. Yun, H. An, Y.-G. Suh
Organic & Biomolecular Chemistry 2016, 14, 1244-1251. Link
08. Synthesis and Synthesis-Based Structural Elucidation of (-)-Macrosphelides J and K
H. An, S.-H. Kim, H. Kim, K. Kim, J. Sim, J. Jang, S.-M. Paek, Y.-G. Suh, H. Yun
Heterocycles 2015, 51, 9026-9029. Link
07. Total Synthesis of (-)-Deguelin via an Iterative Pyran-ring Formation Strategy
S. Lee, H. An, D.-J. Chang, J. Jang, K. Kim, J. Sim, J. Lee, Y.-G. Suh
Chemical Communication 2015, 51, 9026-9029 [IF=6.3]. Link
06. Efficient Strategy for the Stereoselective Synthesis of 2,3-Disubstituted Benzo[α]quinolizidine Alkaloids: Concise Synthesis of (-)-Protoemetinol
H. Moon, H. An, J. Sim, K. Kim, S.-M. Paek, Y.-G. Suh
Tetrahedron Letters 2015, 56, 608-611. Link
05. Design and Synthesis of a Macrosphelide A-Biotin Chimera
H. Yun, J. Sim, H. An, J. Lee, H. S. Lee, Y. K. Shin, S.-M. Paek, Y.-G. Suh
Organic & Biomolecular Chemistry 2014, 12, 7127-7135. Link
04. Microwave-assisted Synthesis of 3-Substituted Indoles via Intramolecular Arene-alkene Coupling of o-Iodoanilino Enamines
W.-I. Lee, J.-W. Jung, J. Sim, H. An, Y.-G. Suh
Tetrahedron 2013, 35, 7211-7219. Link
03. Achiral Auxiliary-assisted Chiral Transfer via Microwave-accelerated Aza-Claisen Rearrangement: A Short Synthesis of (+)-1-Hydroxyquinolizidinone
J. Sim, H. Yun, J.-W. Jung, S. Lee, N.-J. Kim, Y.-G. Suh
Tetrahedron Letters 2012, 53, 4813-4815 Link
02. Asymmetric Formal Synthesis of Schulzeines A and C
J. Jang, J.-W. Jung, J. Ahn, J. Sim, D.-J. Chang, D.-D. Kim, Y.-G. Suh
Organic & Biomolecular Chemistry 2012, 10, 5202-5204 Link
01. Asymmetric Syntheses of 1-Deoxy-6,8a-di-epi-castanospermine and 1-Deoxy-6-epi-castanospermine
H. Yun, J. Kim, J. Sim, S. Lee, Y. T. Han, D.-J. Chang, D.-D. Kim, Y.-G. Suh
The Journal of Organic Chemistry 2012, 77, 5389-5393. Link
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