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The Sim group aims to the state-of-the-art research that could address problems in drug discovery. We focus on developing powerful organic transformations utilizing photoredox catalysis that could access to novel druglike structure . We are interested in applying this novel transformation in biomolecular modification and chemical library construction for drug development.
The Sim group aims to the state-of-the-art research that could address problems in drug discovery. We focus on developing powerful organic transformations utilizing photoredox catalysis that could access to novel druglike structure . We are interested in applying this novel transformation in biomolecular modification and chemical library construction for drug development.
2024. 03. Synthesis에 논문 게재
"Photoredox Catalyzed Oxidative C-H Alkylation of Glycine Derivatives with 4-alkyl-1,4-dihydropyridines"
2024. 03. Synthesis에 논문 게재
"Photoredox Catalyzed Oxidative C-H Alkylation of Glycine Derivatives with 4-alkyl-1,4-dihydropyridines"
2023. 05. Organic Letters에 논문 게재
"Chemical Glycosylation with p‑Methoxyphenyl (PMP) Glycosides via Oxidative Activation"
2023. 05. Organic Letters에 논문 게재
"Chemical Glycosylation with p‑Methoxyphenyl (PMP) Glycosides via Oxidative Activation"
2022. 12. Dr. Madala Hari Babu European Journal of Organic Chemistry에 논문 게재
"Persulfate-Mediated Oxidative C-H Functionalization of Glycinates to Access Diverse Unnatural Amino Acids"
2022. 12. Dr. Madala Hari Babu European Journal of Organic Chemistry에 논문 게재
"Persulfate-Mediated Oxidative C-H Functionalization of Glycinates to Access Diverse Unnatural Amino Acids"
2022. 09. Dr. Madala Hari Babu European Journal of Organic Chemistry에 논문 게재
"Radical-Mediated C-H Alkylation of Glycine Derivatives: A Straightforward Strategy for Diverse α-Unnatural Amino Acids"
2022. 09. Dr. Madala Hari Babu European Journal of Organic Chemistry에 논문 게재
"Radical-Mediated C-H Alkylation of Glycine Derivatives: A Straightforward Strategy for Diverse α-Unnatural Amino Acids"
2022. 01. 장은빈 학생 The Journal of Organic Chemistry에 논문 게재
"Photoredox-Catalyzed Oxidative Radical-Polar Crossover Enables the Alkylfluorination of Olefins"
2022. 01. 장은빈 학생 The Journal of Organic Chemistry에 논문 게재
"Photoredox-Catalyzed Oxidative Radical-Polar Crossover Enables the Alkylfluorination of Olefins"
2021.07. "Evaluation of Anti-Melanogenesis Activity of Enriched Pueraria lobata Stem Extracts and Characterization of Its Phytochemical Components Using HPLC–PDA–ESI–MS/MS" has been published in International Journal of Molecular Sciences
2021.06. 한국연구재단 기초연구실(BRL) 과제 선정
2021.05. "Effect of citric acid and heat treatment on the content of less-polar ginsenosides in flower buds of Panax ginseng" has been published in Preparative Biochemistry & Biotechnology
2021.03. 개인기초연구(우수신진연구) 과제 선정
2021.03. "A Review of the Pharmacological Activities and Recent Synthetic Advances of γ-Butyrolactones" has been published in International Journal of Molecular Sciences
2021.02. "Recent advances in development of hetero-bivalent kinase inhibitors " has been published in European Journal of Medicinal Chemistry
In Sim's laboratory, we are conducting research on all fields of pharmacy using organic synthesis such as photoreduction catalytic reaction development, chemical modification of biomolecule, natural product synthesis, and pharmaceutical chemistry.
Please contact us with many support from interested graduated, undergraduated students and postdoc.
In Sim's laboratory, we are conducting research on all fields of pharmacy using organic synthesis such as photoreduction catalytic reaction development, chemical modification of biomolecule, natural product synthesis, and pharmaceutical chemistry.
Please contact us with many support from interested graduated, undergraduated students and postdoc.
본 연구실에서는 광환원 촉매반응개발, Biomlecule의 chemical modification, 천연물 전합성, 의약화학 등 유기합성을 이용한 약학 전분야에 대한 연구를 수행하고 있습니다. 관심있는 학생, 박사후 연구원 의 많은 지원과 연락 바랍니다.
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