Funding
2025 "Heeyoung Academic Research Grant" supported by the Konyang University of Korea [Role: PI]
2024 “Sejong Science Fellowship Grants Overseas Training Track” supported by the National Research Foundation of Korea(NRF) funded by Korea Government(Ministry of science and ICT) [Role: PI]
Publications (Click to Google Scholar)
2026
36. Seo, J.; Moon, K.M.; Jeong, H.H.; Park, S.-Y.; Kim, A.; Hwang, J.Y.; Hwang, S.; Park, M.H.; Jung, W.-K.; Park, S.-H.; Kim, H.-R.; Jo, S.-H.; Lee, M.; Lee, B. Inhibitory Effects of Extracellular Vesicles Derived from Sargassum Serratifolium on Melanogenesis Partially by Suppressing Melanin Transport. Marine Drugs 2026, 24, 344.
35. Cheung, C.; Li, Z.; Jo, S.-H.; Lee, S.-H.; Heo, S.C. Dynamic Mechanical Loading Reprograms Meniscus Cell-Derived Extracellular Vesicles to Enhance Their Regenerative Potency. Advanced Materials Interfaces 2026, e00012.
2025
34. Shahid, U.; Vu, T.T.; Kim, S.-H.; Ramamoorthy, S.; Jo, S.-H.; Cho, H.; Lee, S.J.; Park, S.-H.; Lim, K.T. Near-Infrared Responsive, Mesoporous Silica Nanoparticle-Incorporated Injectable Hydrogels for on-Demand Anticancer Drug Delivery Applications. International Journal of Biological Macromolecules 2025, 148556.
33. Vu, T.T.*; Jo, S.-H.*; Shahid, U.; Kim, S.-H.; Kim, B.K.; Lee, G.; Jung, W.-K.; Park, S.-H.; Lim, K.T. NIR/Reduction-Responsive, Extracellular Matrix-Based Injectable Hydrogels for Photothermal and Chemo-Cancer Therapy. Applied Materials Today 2025, 44, 102724. (*: Equal contributions as first authors)
32. Kim, B.K.; Kumar, P.; Yadav, S.; Jo, S.-H.; Kim, S.-H.; Cho, H.; Park, S.-H.; Lim, K.T. Redox-Responsive Core-Cross-Linked Micelles of Miktoarm Maltoheptaose-b-Poly (Furfuryl Methacrylate) for Enhanced Anticancer Drug Delivery. Carbohydrate Polymers 2025, 123808.
31. Nam, Y.; Lee, D.; Woerner, J.; Lee, S.-H.; Lee, M.J.; Jo, S.-H.; Jung, J.; Heo, S.C.; Jo, C.H.; Kim, D. Phenome-Wide Comorbidity Network Analysis Reveals Clinical Risk Patterns in Enthesopathy and Enthesitis. medRxiv 2025.
30. Jo, S.-H.; Kim, S.-H.; Heo, S.C.; Cho, H.; Esfahani, I.J.; Park, S.-H. Exploring the Therapeutic Potential of Extracellular Vesicles Anchored to the Sea Cucumber Extracellular Matrix for Treating Atopic Dermatitis. Biomater Res 2025, 29, 0154.
2024
29. Gholamali, I.; Jo, S.-H.; Han, W.; Lim, J.; Rizwan, A.; Park, S.-H.; Lim, K.T. The Diels-Alder Cross-Linked Gelatin/Dextran Nanocomposite Hydrogels with Silver Nanoparticles for Wound Healing Applications: Synthesis, Characterization, and In Vitro Evaluation. Gels 2024, 10, 408.
28. Gholamali, I.; Vu, T.T.; Jo, S.-H.; Park, S.-H.; Lim, K.T. Exploring the Progress of Hyaluronic Acid Hydrogels: Synthesis, Characteristics, and Wide-Ranging Applications. Materials 2024, 17, 2439.
27. Karthika, V.*; Jo, S.-H.*; Yadav, S.; Reddy, O.S.; Lim, H.G.; Lee, W.-K.; Park, S.-H.; Lim, K.T. Self‐Signal‐Triggered Drug Delivery System for Tumor Therapy Using Cancer Cell Membrane‐Coated Biocompatible Mn3O4 Nanocomposites. Advanced Biology 2024, 2300375. (*: Equal contributions as first authors)
26. Vu, T.T.*; Jo, S.-H.*; Kim, S.-H.; Kim, B.K.; Park, S.-H.; Lim, K.T. Injectable and Multifunctional Hydrogels Based on Poly (N-Acryloyl Glycinamide) and Alginate Derivatives for Antitumor Drug Delivery. ACS Applied Materials & Interfaces 2024, 16, 15322–15335. (*: Equal contributions as first authors)
25. Ali, I.; Rizwan, A.; Vu, T.T.; Jo, S.-H.; Oh, C.-W.; Kim, Y.H.; Park, S.-H.; Lim, K.T. NIR-Responsive Carboxymethyl-Cellulose Hydrogels Containing Thioketal-Linkages for on-Demand Drug Delivery System. International Journal of Biological Macromolecules 2024, 260, 129549.
2023
24. Rizwan, A.; Ali, I.; Jo, S.-H.; Vu, T.T.; Gal, Y.-S.; Kim, Y.H.; Park, S.-H.; Lim, K.T. Facile Fabrication of NIR-Responsive Alginate/CMC Hydrogels Derived through IEDDA Click Chemistry for Photothermal–Photodynamic Anti-Tumor Therapy. Gels 2023, 9, 961.
23. Seo, J.-W., Jo, S.-H., Kim, S.-H., Choi, B.-H., Cho, H., Yoo, J. J. & Park, S.-H. Application of Cartilage Extracellular Matrix to Enhance Therapeutic Efficacy of Methotrexate. Tissue Engineering and Regenerative Medicine 1–13 (2023).
22. Vu, T. T., Yadav, S., Reddy, O. S., Jo, S.-H., Joo, S.-B., Kim, B. K., Park, E. J., Park, S.-H. & Lim, K. T. Reduction-Responsive Chitosan-Based Injectable Hydrogels for Enhanced Anticancer Therapy. Pharmaceuticals 16, 841 (2023).
21. Rizwan, A., Gulfam, M., Jo, S.-H., Seo, J.-W., Ali, I., Vu, T. T., Joo, S.-B., Park, S.-H. & Lim, K. T. Gelatin-based NIR and reduction-responsive injectable hydrogels cross-linked through IEDDA click chemistry for drug delivery application. European Polymer Journal 191, 112019 (2023).
20. Vu, T. T., Gulfam, M., Jo, S.-H., Rizwan, A., Joo, S.-B., Lee, B., Park, S.-H. & Lim, K. T. The effect of molecular weight and chemical structure of cross-linkers on the properties of redox-responsive hyaluronic acid hydrogels. International Journal of Biological Macromolecules 238, 124285 (2023).
19. Yadav, S., Ramesh, K., Reddy, O. S., Karthika, V., Kumar, P., Jo, S.-H., Yoo, S. I., Park, S.-H. & Lim, K. T. Redox-Responsive Comparison of Diselenide and Disulfide Core-Cross-Linked Micelles for Drug Delivery Application. Pharmaceutics 15, 1159 (2023).
18. Gulfam, M., Jo, S.-H., Vu, T. T., Ali, I., Rizwan, A., Joo, S.-B., Park, S.-H. & Lim, K. T. NIR-degradable and biocompatible hydrogels derived from hyaluronic acid and coumarin for drug delivery and bio-imaging. Carbohydrate Polymers 120457 (2022).
17. Kumar, P., Kim, S.-H., Yadav, S., Jo, S.-H., Yoo, S., Park, S.-H. & Lim, K. T. Redox-Responsive Core-Cross-Linked Micelles of Miktoarm Poly (ethylene oxide)-b-poly (furfuryl methacrylate) for Anticancer Drug Delivery. ACS Applied Materials & Interfaces (2023).
16. Singh, A. A., Jo, S.-H., Kiddane, A. T., Niyonizigiye, I. & Kim, G.-D. Indole‐3‐carbinol induces apoptosis in AGS cancer cells via mitochondrial pathway. Chemical Biology & Drug Design (2023).
15. Lee, S.-H., Jo, S.-H., Kim, S.-H., Kim, C.-S. & Park, S.-H. Anti-Osteoarthritic Effects of Cartilage-Derived Extracellular Matrix in a Rat Osteoarthritis Model. Tissue Engineering and Regenerative Medicine 20, 83–92 (2023).
2022
14. Kim, S.-H., Jo, S.-H., Kim, B. K. & Park, S.-H. Tissue Engineered Mini-Cornea Model for Eye Irritation Test. Tissue Engineering and Regenerative Medicine 1–11 (2022).
13. Gulfam, M.*, Jo, S.-H.*, Jo, S.-W., Vu, T. T., Park, S.-H. & Lim, K. T. Highly porous and injectable hydrogels derived from cartilage acellularized matrix exhibit reduction and NIR light dual-responsive drug release properties for application in antitumor therapy. NPG Asia Materials 14, 1–17 (2022). (*: Equal contributions as first authors)
12. Ali, I., Gulfam, M., Jo, S.-H., Seo, J.-W., Rizwan, A., Park, S.-H. & Lim, K. T. Reduction-responsive and bioorthogonal carboxymethyl cellulose based soft hydrogels cross-linked via IEDDA click chemistry for cancer therapy application. International Journal of Biological Macromolecules 219, 109–120 (2022).
11. Joo, S.-B., Gulfam, M., Jo, S.-H., Jo, Y.-J., Vu, T. T., Park, S.-H., Gal, Y.-S. & Lim, K. T. Fast Absorbent and Highly Bioorthogonal Hydrogels Developed by IEDDA Click Reaction for Drug Delivery Application. Materials 15, 7128 (2022).
10. Hoang, H. T., Vu, T. T., Karthika, V., Jo, S.-H., Jo, Y.-J., Seo, J.-W., Oh, C.-W., Park, S.-H. & Lim, K. T. Dual cross-linked chitosan/alginate hydrogels prepared by Nb-Tz ‘click’reaction for pH responsive drug delivery. Carbohydrate Polymers 288, 119389 (2022).
9. Ramesh, K., Yadav, S., Mishra, A. K., Jo, S.-H., Park, S.-H., Oh, C.-W. & Lim, K. T. Interface‐cross‐linked micelles of poly (D, L‐lactide)‐b‐poly (furfuryl methacrylate)‐b‐poly (N‐acryloylmorpholine) for near‐infrared‐triggered drug delivery application. Polymers for Advanced Technologies 33, 2137–2148 (2022).
8. Jo, Y.-J., Gulfam, M., Jo, S.-H., Gal, Y.-S., Oh, C.-W., Park, S.-H. & Lim, K. T. Multi-stimuli responsive hydrogels derived from hyaluronic acid for cancer therapy application. Carbohydrate Polymers 286, 119303 (2022).
7. Yadav, S., Kumar, P., Jo, S.-H., Park, S.-H., Lee, W.-K., Yoo, S. I. & Lim, K. T. Redox-responsive properties of core-cross-linked micelles of poly (ethylene oxide)-b-poly (furfuryl methacrylate) for anticancer drug delivery application. Reactive and Functional Polymers 175, 105271 (2022).
6. Vu, T. T., Gulfam, M., Jo, S.-H., Park, S.-H. & Lim, K. T. Injectable and biocompatible alginate-derived porous hydrogels cross-linked by IEDDA click chemistry for reduction-responsive drug release application. Carbohydrate Polymers 118964 (2021).
5. Kim, T.-H., Heo, S.-Y., Oh, G.-W., Park, W. S., Choi, I.-W., Kang, H. W., Kim, H.-W., Kim, Y.-M., Jo, S.-H. & Park, S.-H. A phlorotannins‐loaded homogeneous acellular matrix film modulates post‐implantation inflammatory responses. Journal of Tissue Engineering and Regenerative Medicine 16, 51–62 (2022).
2021
4. Yadav, S., Ramesh, K., Kumar, P., Jo, S.-H., Yoo, S. I., Gal, Y.-S., Park, S.-H. & Lim, K. T. Near-Infrared Light-Responsive Shell-Crosslinked Micelles of Poly (d, l-lactide)-b-poly ((furfuryl methacrylate)-co-(N-acryloylmorpholine)) Prepared by Diels–Alder Reaction for the Triggered Release of Doxorubicin. Materials 14, 7913 (2021).
3. Jo, S.-H., Kim, S.-H., Kim, C. & Park, S.-H. Characterization of Marine Organism Extracellular Matrix-Anchored Extracellular Vesicles and Their Biological Effect on the Alleviation of Pro-Inflammatory Cytokines. Marine Drugs 19, 592 (2021).
2. Hoang, H. T., Jo, S.-H., Phan, Q.-T., Park, H., Park, S.-H., Oh, C.-W. & Lim, K. T. Dual pH-/thermo-responsive chitosan-based hydrogels prepared using" click" chemistry for colon-targeted drug delivery applications. Carbohydrate Polymers 260, 117812 (2021).
1. Jo, S.-H., Kim, C. & Park, S.-H. Novel Marine Organism-Derived Extracellular Vesicles for Control of Anti-Inflammation. Tissue Engineering and Regenerative Medicine 18, 71–79 (2021).
Patents
Sung-Han Jo, Won-Sang Yun, Seong-Jun Jung, and Sang-Hyug park “Tear collecting lens” (Number: 1020314880000)
Sung-Han Jo, Changsu Kim, and Sang-Hyug Park “Enhanced functional Pharmaceutical composition of extracellular vesicles derived marine animal” (Number: 1020220051297)
Sung-Han Jo, Changsu Kim, Sang-Hun Lee, and Sang-Hyug Park “Pharmaceutical composition for preventing or treating osteoarthritis comprising extracellular matrix derived cartilage tissue” (Number: 1020220051298)
Sung-Han Jo, Seon-Hwa Kim, and Sang-Hyug Park “Composition for preventing and treating atopic dermatitis comprising extracellular vesicles derived from sea cucumbers” (Number: 1020240003301)
Sung-Han Jo, Seon-Hwa Kim, and Sang-Hyug Park “Extracellular matrix derived cartilage tissue based hydrogel and method for preparing the same” (Number: 1020240014570)
Sung-Han Jo, Seon-Hwa Kim, and Sang-Hyug Park "Injectable tissue regenerative therapeutic comprising extracellular matrix synthesized by tenocytes" (Number: 1020250126196)
Technology Transfer
Transferred “Composition for preventing and treating atopic dermatitis comprising extracellular vesicles derived from sea cucumbers” patent to Glopex Co., Ltd.
Transferred “Pharmaceutical composition for preventing or treating osteoarthritis comprising extracellular matrix derived cartilage tissue” patent to ATEMs Co., Ltd.