Mechanically-induced Septin Networks Protect Nuclear Integrity
Margaret E Utgaard, Alexia Caillier, Shreya Chandrasekar, Joseph J Tidei, Harikrushnan Balasubramanian, Rachel M Lee, Owen Puls, Satya Khuon, Jesse Aaron, Teng-Leong Chew, Jordan R Beach*, Patrick W Oakes*
bioRxiv in revision
Smooth Muscle Myosin 2 Filaments Dynamically Assemble and Stabilize During Induced Contractility
Sasha K. Demeulenaere, Margaret A. Bennett, Bradley Somerfield, Huini Wu, Margaret E. Utgaard, Hiral Patel, Stefano Sala, Elizabeth R. Longtine, Ahmed Zied, Jonathan A. Kirk, Patrick W. Oakes, Jordan R. Beach.
bioRxiv resubmitted
Local RhoA activation induces anillin-independent septin recruitment in interphase cells
Shreya Chandrasekar, Margaret E Utgaard, Bradley Somerfield, Huini Wu, Jordan R Beach*, Patrick W Oakes*
MBoC 2025
Myosin 2 – A general contractor for the cytoskeleton
Tidei, J. J., Oakes, P.W., Beach, J.R.
Curr Opin Cell Biol 2025
Non-muscle myosin 2 can incorporate into established filaments in cells without an assembly competence domain
Wu K., Patel H., Wu H., Quintanilla, M.A., Bennett M.A., Sala S.*, Beach J.R.*
MBoC 2025
Local Monomer Levels and Established Filaments Potentiate Non-Muscle Myosin 2 Assembly
Quintanilla M. A., Patel H., Wu H., Sochacki K. A., Akamatsu M., Rotty J. D., Korobova F., Bear J. E., Taraska J. W., Oakes P. W.*, & Beach J. R.*
J Cell Biol. 2024
Non-muscle myosin 2 at a glance
Quintanilla MA, Hammer JA, Beach JR.
J Cell Sci. 2023
Non-muscle myosin 2 filaments are processive in cells
Eric A. Vitriol, Melissa A. Quintanilla, Joseph J. Tidei, Lee D. Troughton, Abigail Cody, Bruno A. Cisterna, Makenzie L. Jane, Patrick W. Oakes, Jordan R. Beach.
Biophys J. 2023
Pulling in new directions: Myosin 2, Piezo, and metabolism
Quintanilla, MA, Hammer JA, and Beach, JR.
F1000 Review. 2019
LIM Domain Proteins link molecular and global tension by recognizing strained actin in adhesions
Stefano Sala, View ORCID Shreya Chandrasekar, Lee Troughton, Huini Wu, Jordan R. Beach, Patrick W. Oakes
Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract
Alexander J. Nelson, Tatematsu K. Bruna, Jordan R. Beach, Dorothy K. Sojka, Yee Ling Wu.
A glyoxal-specific aldehyde signaling axis in Pseudomonas aeruginosa that influences quorum sensing and infection
Christopher J Corcoran, Bonnie J Cuthbert, David G Glanville, Mailyn Terrado, Diana Valverde Mendez, Benjamin P Bratton, Daniel E Schemenauer, Valerie L Tokars, Thomas G Martin, Lawrence W Rasmussen, Matthew C Madison, Andrew F Maule, Joshua W Shaevitz, Boo Shan Tseng, Julian P Whitelegge, Catherine Putonti, Amit Gaggar, Jordan R Beach, Jonathan A Kirk, Alfonso Mondragón , Abby R Kroken, Jonathan P Allen, Celia W Goulding, Andrew T Ulijasz
Nat Comms 2025
The PCM scaffold enables RNA localization to centrosomes
Junnan Fang, Weiyi Tian, Melissa A. Quintanilla, Jordan R. Beach, Dorothy A. Lerit.
MBoC 2025
Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling.
Wang H, Hou W, Perera A, Bettler C, Beach JR, Ding X, Li J, Denning MF, Dhanaraja A, Cotler SJ, Joyce C, Yin J, Ahmed F, Roberts LR, Qiu W.
Cell Rep. 2021
Conditional Myh9 and Myh10 inactivation in adult mouse renal epithelium results in progressive kidney disease
Otterpohl KL, Busselman BW, Ratnayake I, Hart RG, Hart K, Evans C, Phillips CL, Beach JR, Ahrenkiel P, Molitoris B, Surendran K, Chandrasekar I.
JCI Insight. 2020
Inhibitory and stimulatory micropeptides preferentially bind to different conformations of the cardiac calcium pump
Cleary SR, Fang X, Cho EE, Pribadi MP, Seflova J, Beach JR, Kekenes-Huskey PM, Robia SL.
J Biol Chem. 2022
Re-evaluating the roles of myosin 18Aα and F-actin in determining Golgi morphology
Bruun K*, Beach JR*, Remmert K, and Hammer JA. Cytoskeleton (Hoboken). 2017 *indicates equal contribution
Actin Dynamics and Competition for Myosin Monomer Govern the Sequential Amplification of Myosin Filaments
Beach JR, Kyle Bruun, Lin Shao, Dong Li, Zac Swider, Kirsten Remmert, Yingfang Zhang, Mary Anne Conti, Robert Adelstein, Nasser Rusan, Eric Betzig, John Hammer. Nat Cell Biol. 2017
Myosin II Coassembly and Isoform-Specificity in Mammalian Systems
Beach JR and Hammer 3rd JA. Exp Cell Res. Review. 2015
Myosin 18A Coassembles with Nonmuscle Myosin 2 to Form Mixed Bipolar Filaments
Billington N*, Beach JR*, Heissler SM, Guzik-Lendrum S, Nagy A, Takagi Y, Shao L, Li D, Remmert K, Yang Y, Barzik M, Betzig E, Hammer 3rd JA, Sellers JR. Curr Biol. 2015 *indicates equal contribution
Non-muscle Myosin II Isoforms Coassemble in Living Cells
Beach JR*, Shao L, Remmert K, Li D, Betzig E, Hammer 3rd J*. Curr Biol. 2014 *co-corresponding author