Jitendra Maharana, Ph.D.
Structural Biologist
Cryo-EM | Computational Biophysics
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NEWS
NEWS
New article entitled "Cryo-EM and cryo-ET reveal the molecular architecture and host interactions of mycobacteriophage Douge" published on 24th July, 2025 in Cell Reports. 👇🏽
ABOUT ME
I am currently a Postdoctoral Researcher at the Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan. My research integrates structural biology and computational biophysics to dissect the molecular mechanisms of the phage–host interactions. By applying Cryo-EM, Cryo-ET, and MD simulations, I am currently studying the structure and dynamics of bacteriophage sub-components and delineating their key role in phage–host interaction. The finding would provide foundation for future mycobacterium phage-engineering efforts.
EDUCATION
Ph.D. in Structural Biology | 2018 - 2025
Academia Sinica, Taipei & National Tsing Hua University, Hsinchu, Taiwan
M.Sc. in Bioinformatics | 2009 - 2011
Orissa University of Agriculture and Technology, Bhubaneswar, Odisha, India
B.Sc. in Botany (Honours) | 2006 - 2009
Nayagarh Autonomous College (Utkal University), Nayagarh, Odisha, India
RESEARCH EXPERIENCE
Postdoctoral Researcher - Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan. (Aug. 2025 – Ongoing)
Senior Research Fellow - Dept. of Agricultural Biotechnology, Assam Agricultural University, India. (2016 – 2018)
Worked on AGPase subunit interactions and eIF4A1–ATP binding in rice. Also contributed to structure-based lead identification targeting MabA protein of M. tuberculosis. (Published three first/co-first author articles)
Independent researcher - Dept. of Bioinformatics, Orissa University of Agriculture and Technology, Bhubaneswar, India. (2014 – 2016)
Independently investigated death domain interactions (CARDs/PYDs) and the ATP/ADP-bound dynamics of NLRP proteins. (Published seven first/co-first authored articles)
Senior Research Fellow - Biotechnology Lab., Central Inland Fisheries Research Institute, Barrackpore, India. (2012 – 2014)
Studied the how zebrafish NOD1/2 interacts with PGNs, ATP and adaptor molecule. (Published four first-authored articles)
Assistant (Project) - Fish Immunology Lab., Central Institute of Freshwater Aquaculture, Bhubaneswar, India. (2011 – 2012)
Studied NOD2-MDP interaction using molecular modeling approaches. (Published one co-first-authored article)
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