Publications

Full Publication List
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indicates co-first authors and * indicates (co-)corresponding authors.

25.  Jeongcheol Shin,* Mi Hee Lim,* and Jiyeon Han* Bull. Korean Chem. Soc. 2024, 45, 593.
"NMR Spectroscopic Investigations of Transition Metal Complexes in Organometallic and Bioinorganic Chemistry"

24. Daeun Shim and Jiyeon Han* BMB Rep. 2023, 56, 575-583.
"Coordination Chemistry of Mitochondrial Copper Metalloenzymes: Exploring Implications for Copper Dyshomeostasis in Cell Death"

23Eunju Nam, Yuxi Lin, Jiyong Park, Hyunsu Do, Jiyeon Han, Bohyeon Jeong, Subin Park, Da Yong Lee, Mingeun Kim, Jinju Han,* Mu-Hyun Baik,* Young-Ho Lee,* Mi Hee Lim* Adv. Sci. 2023, 2307182.
"APP-C31: An Intracellular Promoter of Both Metal-Free and Metal-Bound Amyloid-β40 Aggregation and Toxicity in Alzheimer's Disease"

22.  Jiyeon Han* Dalton Trans. 2023, 52, 15277-15296.
  "Copper Trafficking System in Cells: Insights into Coordination Chemistry and Toxicity"

21.  Jeasang Yoo, Jiyeon Han,* Mi Hee Lim* RSC Chem. Biol. 2023, 4, 548.
  "Transition Metal Ions and Neurotransmitters: Coordination Chemistry, and Implications for Neurodegeneration"

20.  Seongmin Park, Chanju Na, Jiyeon Han,* Mi Hee Lim* Metallomics 2023, 15, mfac102.
  "Methods for Analyzing the Coordination and Aggregation of Metal–Amyloid-β"

19.  Jong-Min Suh, Mingeun Kim, Jeasang Yoo, Jiyeon Han, Cinthya Paulina, Mi Hee Lim* Coord. Chem. Rev. 2023, 478, 214978.
"Intercommunication between Metal Ions and Amyloidogenic Peptides or Proteins in Protein Misfolding Disorders"

18.   Jiyeon Han, Jiwon Yoon, Jeongcheol Shin, Eunju Nam, Tongrui Qian, Yulong Li, Kiyoung Park,* Seung-Hee Lee,* Mi Hee Lim* Nat. Chem. 2022, 14, 1021–1030.
“Conformational and Functional Changes of the Native Neuropeptide Somatostatin Occur in the Presence of Copper and Amyloid-β”
*Note: This paper was highlighted in multiple media. [Link]🖱️

17.   Jiyeon Han, Zhi Du, Mi Hee Lim* Acc. Chem. Res. 2021, 54, 3930–3940.
“Mechanistic Insight into the Design of Chemical Tools to Control Multiple Pathogenic Features in Alzheimer’s Disease”

16.   Eunju Nam, Jiyeon Han, Sunhee Choi, Mi Hee Lim* Chem. Commun. 2021, 57, 7637–7640.
“Distinct Impact of Glycation towards the Aggregation and Toxicity of Murine and Human Amyloid-β”
*Note: This paper was contributed to the Special Issue of "Multimolecular Crowding in Biosystems".

15.   Yelim Yi, Yuxi Lin, Jiyeon Han, Hyuck Jin Lee, Nahye Park, Geewoo Nam, Young S. Park, Young-Ho Lee,* Mi Hee Lim* Chem. Sci. 2021, 12, 2456–2466. (Co-authorship)
“Impact of Sphingosine and Acetylsphingosines on the Aggregation and Toxicity of Metal-free and Metal-induced Amyloid-β”

14.   Jiyeon Han, Hyuck Jin Lee, Kyu Yeon Kim, Geewoo Nam, Junghyun Chae, Mi Hee Lim* Proc. Natl. Acad. Sci. U. S. A. 2020, 117, 5160–5167.
“Mechanistic Approaches for Chemically Modifying the Coordination Sphere of Copper–Amyloid-β Complexes”
*Note: This paper was highlighted in multiple media. [Link]🖱️

13.   Mingeun Kim, Juhye Kang, Misun Lee, Jiyeon Han, Geewoo Nam, Eunyoung Tak, Min Sun Kim, Hyuck Jin Lee, Eunju Nam, Jiyong Park, Soo Jin Oh, Ji-Yoon Lee, Joo-Yong Lee,* Mu-Hyun Baik,* Mi Hee Lim* J. Am. Chem. Soc. 2020, 142, 8183–8193.
“Minimalistic Principles for Designing Small Molecules with Multiple Reactivities against Pathological Factors in Dementia”
*Note: This paper was selected as the “ACS Editors' Choice" 

12.   Yelim Yi, Jiyeon Han, Min Hee Park, Nahye Park, Eunju Nam, Hee Kyung Jin,* Jae-sung Bae,* Mi Hee Lim* Chem. Commun. 2019, 55, 5847–5850.
“Tunable Regulatory Activities of 1,10-Phenanthroline Derivatives towards Acid Sphingomyelinase and Zn(II)–Amyloid-β”
*Note: This paper was featured as the “Front Cover”.

11.   Min Seon Kim, Tae Geun Jo, Minuk Yang, Jiyeon Han, Mi Hee Lim,* Cheal Kim* Spectrochim. Acta A Mol. Biomol. Spectrosc. 2019, 211, 34–43.
“A Fluorescent and Colorimetric Schiff Base Chemosensor for the Detection of Zn2+ and Cu2+: Application in Live Cell Imaging and Colorimetric Test Kit”

10.   Jiyeon Han, Hyuck Jin Lee, Kyu Yeon Kim, Shin Jung C. Lee, Jong-Min Suh, Jaeheung Cho, Junghyun Chae,* Mi Hee Lim* ACS Chem. Neurosci. 2018, 9, 800–808.
“Tuning Structures and Properties for Developing Novel Chemical Tools towards Distinct Pathogenic Elements in Alzheimer’s Disease”

9.   Eunju Nam, Jiyeon Han, Jong-Min Suh, Yelim Yi, Mi Hee Lim* Curr. Opin. Chem. Biol. 2018, 43, 8–14.
“Link of Impaired Metal Ion Homeostasis to Mitochondrial Dysfunction in Neurons”

8.    Ji Hye Kang, Jiyeon Han, Hyojin Lee, Mi Hee Lim,* Ki-Tae Kim, Cheal Kim* Dyes Pigm. 2018, 152, 131–138.
“A Water-soluble Fluorescence Chemosensor for the Sequential Detection of Zn2+ and Pyrophosphate in Living Cells and Zebrafish”

7.    Jae Min Jung, Ji Hye Kang, Jiyeon Han, Hyojin Lee, Mi Hee Lim, Ki-Tae Kim,* Cheal Kim* Sens. Actuators B Chem. 2018, 267, 58–69.
“A Novel “Off-on” Type Fluorescent Chemosensor for Detection of Zn2+ and Its Zinc Complex for “On-off” Fluorescent Sensing of Sulfide in Aqueous Solution, In Vitro and In Vivo

6.    Jin Yeong Yun, Tae Geun Jo, Jiyeon Han, Hyo Jung Jang, Mi Hee Lim, Cheal Kim* Sens. Actuators B Chem. 2018, 255, 3108–3116.
“A Highly Sensitive and Selective Fluorescent Chemosensor for the Sequential Recognition of Zn2+ and S2- in Living Cells and Aqueous Media”

5.    Eunju Nam, Jeffrey S. Derrick, Seunghee Lee, Juhye Kang, Jiyeon Han, Shin Jung C. Lee, Su Wol Chung,* Mi Hee Lim* ACS Chem. Neurosci. 2018, 9, 2655–2666.
"Regulatory Activities of Dopamine and Its Derivatives towards Metal-free and Metal-induced Amyloid-β Aggregation, Oxidative Stress, and Inflammation in Alzheimer’s Disease"

4.    Tae Geun Jo, Jae Min Jung,* Jiyeon Han, Mi Hee Lim, Cheal Kim* RSC Adv. 2017, 7, 28723–28732.
“A Single Fluorescent Chemosensor for Multiple Targets Cu2+, Fe2+/3+ and Al3+ in Living Cells and a Near-Perfect Aqueous Solution”

3.    Ha Yeong Jeong, Seong Yeol Lee,* Jiyeon Han, Mi Hee Lim,* Cheal Kim* Tetrahedron 2017, 73, 2690–2697.
“Thiophene and Diethylaminophenol-based “Turn-on” Fluorescence Chemosensor for Detection of Al3+ and F- in a Near-Perfect Aqueous Solution”

2.    Tae Geun Jo, Kwon Hee Bok, Jiyeon Han, Mi Hee Lim, Cheal Kim* Dyes Pigm. 2017, 139, 136–147.
"Colorimetric Detection of Fe3+ and Fe2+ and Sequential Fluorescent Detection of Al3+ and Pyrophosphate by an Imidazole-based Chemosensor in a Near-Perfect Aqueous Solution"

1.     Michael W. Beck, Jeffrey S. Derrick, Richard A. Kerr, Shin Bi Oh, Woo Jong Cho, Shin Jung C. Lee, Yonghwan Ji, Jiyeon Han, Zahra Aliakbar Tehrani, Nayoung Suh, Sujeong Kim, Scott D. Larsen, Kwang S. Kim,* Joo-Yong Lee,* Brandon T. Ruotolo,* Mi Hee Lim* Nat. Commun. 2016, 7, 13115.
"Structure-Mechanism-Based Engineering of Chemical Regulators for Distinct Pathological Factors in Alzheimer’s Disease"
*Note: This paper was highlighted in multiple media. [Link]🖱️