LIST OF FULL PUBLICATIONS

2025

1. Park, S. & Lee,J. M. (2025) Deubiquitinase dynamics: methodologies for understanding substrate interactions, BMB Reports, 58(5): 191-202

2. Lee, I., Kim, G. M.,  Kim, J.,  Lee, B.,  Lee, J. M.,  Lee, D. C. (2025) Penicillamine-induced decomposition of copper sulfide nanocrystals after microbial infection treatment, Chemical Engineering Journal https://doi.org/10.1016/j.cej.2024.159195

2024

1. Oh, J., Park, S., Kim, J., Yeom, S., Lee, J.M., Lee, E.J., Cho, Y.J., Lee, J.S. (2024) Swd2/Cps35 determines H3K4 tri-methylation via interactions with Set1 and Rad6, BMC biology, 22(1), 105 

2023

1. Yang, S.M.#, Kim, J.#, Lee, J-Y.#, Lee, J-S.*, Lee, J.M.* (2023) Regulation of glucose and glutamine metabolism to overcome cisplatin resistance in intrahepatic cholangiocarcinoma, BMB reports, 56 (11), 600-605 (# : Equal contribution, *: Co-correspondence).

2. Lee, J.H.#, Park, S-A.#, Park, I-G., Yoon, B.K., Lee, J-S.*, Lee, J.M.* (2023) Stem Cell Properties of Gastric Cancer Stem-Like Cells under Stress Conditions Are Regulated via the c-Fos/UCH-L3/β-Catenin Axis, Molecules and Cells, 46 (8), 476-485 (# : Equal contribution, *: Co-correspondence).

3. Lee, J. M., Hammarén, H.M., Savitski, M.M., and Baek, S.H. (2023) Control of Protein Stability by Posttranslational Modifications. Nature Communications, 14 (1), 201 DOI: 10.1038/s41467-023-35795-8

관련 기사:

https://news.kaist.ac.kr/news/html/news/?mode=V&mng_no=26710

https://ibric.org/myboard/read.php?Board=news&id=348636&ksr=1&FindText=%EC%9D%B4%EC%A7%80%EB%AF%BC

https://www.yna.co.kr/view/AKR20230201031400063?input=1195m

4. Im, H.#, Baek, H. J.#, Yang, E., Kim, K., Oh, S. K., Lee, J. S., Kim, H.*, Lee, J. M.* (2023) ROS inhibits RORα degradation by decreasing its arginine methylation in liver cancer. Cancer Science 114 (1), 791-805 (# : Equal contribution, *: Co-correspondence).

2022

1. Shin, C-H.#, Park, S. C.#, Park, I-G., Kim, H., Lee, C., Kim, S-H., Lee, J.*, Lee, J. M.*, Oh, S. J.* (2022) Cytosolic microRNA-inducible nuclear translocation of Cas9 protein for disease-specific genome modification Nucleic Acids Research  50 (10), 5919-5933 (# : Equal contribution, *: Co-correspondence).

관련 기사:

국내 연구진, 질병 세포만 쏙쏙 노리는 유전자 가위 개발 : 동아사이언스 (dongascience.com)

KAIST, 질병세포만 찾아 교정 치료 가능...유전자 가위 시스템 개발 < 뉴스플러스 < 대학일반 < 대학뉴스 < 기사본문 - 대학저널 (dhnews.co.kr)

질병 세포만 찾아 절단…KAIST, 유전자 가위 '셀프 체크인' 개발 | 연합뉴스 (yna.co.kr)

NEWS (kaist.ac.kr)

https://gsmse.kaist.ac.kr/boards/view/board_news/12921

메디소비자뉴스 (medisobizanews.com)

2. Park, I-G., Jeon, M., Kim, H.*, and Lee, J. M.* (2022) Coordinated Methyl Readers: Functional Communications in Cancer. Semin Cancer Biol 83, 88-99 (*: Co-correspondence).

관련 기사: http://www.kangwon.ac.kr/www/selectBbsNttView.do?bbsNo=249&nttNo=143667&key=100

한빛사 링크: https://www.ibric.org/hanbitsa/treatise_index_for_author.php?idauthorid=7906

----- Starting New Job position @ KAIST -----

3. Park, S. C., and Lee, J. M. (2022) Ezh2 promotes TRβ lysine methylation-mediated degradation in hepatocellular carcinoma. Genes & Genomics  44, 369-377.

2021

1. Lee, J. M., Kim, H., and Baek S. H. (2021) Unraveling the physiological roles of retinoic acid receptor-related orphan receptor α. Experimental & Molecular Medicine 53, 1278-1286.

2020

1. Oh, S. R.# , Boo, K.# , Kim, J., Baek, S. A., Jeon, Y., You, J., Lee, H., Choi, H-J, Park, D.*,  Lee, J. M.*, Baek, S. H.* (2020) The chromatin-binding protein PHF6 functions as an E3 ubiquitin ligase of H2BK120 via H2BK12Ac recognition for activation of trophectodermal genes. Nucleic Acids Research 48 (16), 9037-9052 (# : Equal contribution, *: Co-correspondence). 

관련 기사: http://www.hkn24.com/news/articleView.html?idxno=313099

https://bit.ly/2Ec1uWb

2. Lee, I. K.*, Song, H.*, Kim, H., Kim, I. S., Tran, N. L., Kim, S-H.,  Oh, S. J.#, Lee, J. M.# (2020). RORα Regulates Cholesterol Metabolism of CD8+ T cells for Anti-Cancer Immunity. Cancers. 12 (7), 1733. (*: Equal contribution, # : Co-correspondence)

3.  Song, H., Chu. J. W., Park, S. C., Im, H., Park, I-G., Kim, H.*, Lee, J. M.* (2020). Isoform-specific lysine methylation by SET7 of RORα2 is required for association of the TIP60 coactivator complex in prostate cancer progression. Int J Mol Sci. 21 (5), 1622. (* : Co-correspondence)

2019

1. Oh, S. K., Kim, D. H., Kim, K. K., Boo, K. J., Yu, Y. S., Kim, I. S., Jeon, Y., Lee, H., Im, S. -K., Lee, S. -H., Lee, J. M., Ko, Y. H., Park, D. C., Fang, S. S., and Baek, S. H. (2019). RORα Is Crucial for Attenuated Inflammatory Response to Maintain Intestinal Homeostasis. Proc. Natl. Acad. Sci. USA. 116, 21140-21149.

2.  Park, S. C.*, Park, I-G.*, Kim, H., Lee, J. M. (2019). N-terminal Domain Mediated Regulation of RORα1 Inhibits Invasive Growth in Prostate Cancer. Int J Mol Sci. 20 (7), 1684. (* : Equal contribution)

----- Returning to academia after 7 years in industry -----

2017

1. Kim, K.* Lee, J. M.* Yu, Y. S., Kim, H., Nam, H. J., Moon, H. -G., Noh, D. -Y., Kim, K. I., Fang, S., Baek, S. H. (2017). RORα2 requires LSD1 to enhance tumor progression in breast cancer. Sci Rep. 7, 11994. (* : Equal contribution)

2016

1. Lee, J. M., Lee, S. H., Hwang, J. W., Oh, S. J., Kim, B., Jung, S., Shim, S. H., Lin, P. W., Lee, S. B., Cho, M. Y., Koh, Y. J., Kim, S. Y., Ahn, S., Lee, J., Kim, K. M., Cheong, K. H., Choi, J., and Kim, K. -A. (2016). Novel strategy for a bispecific antibody: induction of dual target internalization and degradation. Oncogene. 35, 4437-46.

2. Lee, B. S., Kim, H. J., Hwang, J. W., Cheong, K. H., Kim, K. -A., Cha, H. Y., Lee, J. M., Kim, C. H. (2016). The Dual Inhibition of Met and EGFR by ME22S, a Novel Met/EGFR Bispecific Monoclonal Antibody, Suppresses the Proliferation and Invasion of Laryngeal Cancer. Ann Surg Oncol. 23, 2046-53.

2015

1. Lee, J.*, Ou, S. H.*, Lee, J. M.*, Kim, H. C., Hong, M., Kim, S. Y., Jang, J., Ahn, S., Kang, S. Y., Lee, S., Kim, S. T., Kim, B., Choi, J., Kim, K. -A., Lee, J., Park, C., Park, S. H., Park, J. O., Lim, H. Y., Kang, W. K., Park, K., Park, Y. S., Kim, K. M. (2015). Gastrointestinal malignancies harbor actionable MET exon 14 deletions. Oncotarget. 6, 28211-22. (* : Equal contribution)

2014

1. Oh, Y. M., Lee, S. B., Choi, J., Suh, H. Y., Shim, S., Song, Y. J., Kim, B., Lee, J. M., Oh, S. J., Jeong, Y., Cheong, K. H., Song, P. H., Kim, K. -A. (2014). USP8 modulates ubiquitination of LRIG1 for Met degradation. Sci Rep. 4, 4980.

2. Kim, B., Wang, S., Lee, J. M., Jeong, Y., Ahn, T., Son, D. S., Park, H. W., Yoo, H. S., Song, Y. J., Lee, E., Oh, Y. M., Lee, S. B., Choi, J., Murray, J. C., Zhou, Y., Song, P. H., Kim, K. -A., Weiner, L. M. (2015). Synthetic lethal screening reveals FGFR as one of the combinatorial targets to overcome resistance to Met-targeted therapy. Oncogene. 34, 1083-93. 

3. Lee, J. M., Kim, B., Lee, S.B., Jeong, Y., Oh, Y.M., Song, Y.-J., Jung, S. -Y., Choi, J., Lee, S., Cheong K. H., Kim, D., Park, H. W., Han, Y. K., Kim, G. W., Choi, H., Song, P. H., and Kim, K. (2014). Cbl-independent degradation of Met: ways to avoid agonism of bivalent Met targeting antibody. Oncogene. 33, 34-43.

4. Shin, D., Kim, I. S., Lee, J. M., Shin, S. Y., Lee, J. H., Baek, S. H., Cho, K. H. (2014). The hidden switches underlying RORα-mediated circuits that critically regulate uncontrolled cell proliferation. J Mol Cell BIol. 6, 338-48.

2012

1.  Lee, J. M., Lee, J. S., Kim, H. K., Kim, K., Park, H. J., Kim, J.-Y., Lee, S. H., Kim, I. S., Kim, J.M., Lee, M. K., Chung, C. H., Seo, S.-B., Yoon, J. -B., Ko, E.Y., Noh, D. -Y., Kim, K. I., Kim, K. K., and Baek, S. H. (2012). Ezh2 Generates a Methyl Degron That Is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex. Molecular Cell. 48, 1-15. (Cover Article)

2. Oh, Y. M., Song, Y. J., Lee, S. B., Jeong, Y., Kim, B., Kim, G. W., Kim, K. E., Lee, J. M., Cho, M. Y., Choi, J., Nam, D. H., Song, P. H., Cheong, K. H., Kim, K. -A. (2012). A new anti-c-Met antibody selected by a mechanism-based dual-screening method: therapeutic potential in cancer. Mol Cells. 34, 523-9. 

2011

1. Kim, H., Lee, J. M., Lee, G., Bhin, J., Oh, S. K., Kim, K., Yim, H. Y., Kim, K. K., Hwang, D., Chung, J., and Baek, S. H. (2011). DNA Damage-induced RORα Is Crucial for p53 Stabilization and Increased Apoptosis. Molecular Cell. 44, 797-810.  (Cover Article)

----- The transition from academia to industry -----

2010

1. Lee, J. M., Kim, I. S. Kim, H., Lee, J. S., Kim, K., Yim, H. Y., Jeong, J., Kim, J. H., Kim, J.-Y., Lee, H., Seo, S.-B., Kim, H., Rosenfeld, M. G., Kim, K. I., and Baek, S. H. (2010). RORα Attenuates Wnt/β-Catenin Signaling by PKCα-dependent Phosphorylation in Colon Cancer. Molecular Cell. 37,183-195. (Top Ranking 2nd)

2. Lee, J. S., Kim, Y., Kim, I. S., Kim, B., Choi, H. J., Lee, J. M., Shin, H-J. R., Kim, J. H., Kim, J.-Y., Seo, S.-B., Lee, H., Binda, O., Gozani, O., Semenza, G. L., Kim, M., Kim, K. I., Hwang, D. H., and Baek, S. H. (2010). Negative Regulation of Hypoxic Responses via Induced Reptin Methylation. Molecular Cell. 39,71-85. (Cover Article)

3. Choi, H.J., Lee, J.M., Kim, H.K., Nam, H.J., Shin, H-J.R., Kim, D.H., Ko, E.Y., Noh, D.Y., Kim, K.I., Kim, J.H., and Baek, S.H. (2010) Bcl3-dependent Stabilization of CtBP1 is Crucial for the Inhibition of Apoptosis and Tumor Progression in Breast Cancer. Biochem. Biophys. Res. Comm., 400(3), 396-402

2008

1. Hwang, E.J.*, Lee, J.M.*, Jeong,J., Park,J.H., Yang,Y., Lim, J.S., Kim, J.H., Baek, S.H., and Kim,K.I. (2008). SUMOylation of RORα potentiates transcriptional activation function. Biochem. Biophys. Res. Comm. 378, 513-517. (* : Equal contribution)

2007

1. Kim, J. H., Lee, J. M., Nam, H. J., Choi, H. J., Yang, J. W., Lee, J. S., Kim, M. H., Kim, S.-I., Chung, C. H., Kim, K. I., and Baek, S. H. (2007). SUMOylation of a pontin chromatin-remodeling complex reveals a new signal integration code in prostate cancer. Proc. Natl. Acad. Sci. USA. 104, 20793-20798.

2006

1. Kim, J. H., Choi, H. J., Kim, B., Kim, M. H., Lee, J. M., Kim, I. S., Lee, M. H., Choi, S. J., Kim, K. I., Kim, S.-I., Chung, C. H., and Baek, S. H. (2006). Roles of SUMOylation of a Reptin Chromatin Remodeling Complex in Cancer Metastasis. Nature Cell Biol. 8, 631-639.