Embedded Files
1. Joung J., Kirchgatterer P., Singh A., Cho J.H., Nety S., Larson R., Deasy R., Tseng Y., Maus M., Zhang F. CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Nature Communications 13, 1606 (2022).
2. Cho J.H.*, Okuma A.*, Sofjan K., Lee S., Collins J.J., Wong W.W. Engineering Advanced Logic and Distributed Computing in Human Immune Cells. Nature Communications 12, 792 (2021).
3. Weinberg B.H., Cho J.H., Agarwal Y., Pham H., Caraballo L.D., Walkosz M., Ortega C., Trexler M., Tague N., Law B., Benman WKJ., Letendre J., Jacob Beal J., Wong W.W. (2019). High-performance chemical and light-inducible recombinases in mammalian cells and mice. Nature Communications. 10, 4845.
4. Cho J.H., Collins J.J., Wong W.W. (2018). Universal chimeric antigen receptors for multiplexed and logical control of T cell responses. Cell 173, 1426–1431.e11.
News coverage & Research highlights
- Souped-up T cells home in on cancer. Nature, (2018)
- Miura G., ZIPing around CARs. Nature Chemical Biology, 14, 637 (2018).
- Fierce Biotech article “CAR-T 2.0? A split, universal and programmable system”
- GEN News article “Controllable “Swiss Army Knife” CAR T Cells Solve Key Efficacy and Safety Issues”
- Medical Xpress article “Upgrading the immune system to fight cancer”
- ecancer News article “Customising CAR T methods to upgrade the immune system”
- Biocentury article “Senti co-founders describe tunable CAR T system”
- News Medical article “New CAR-T therapy could provide safer, more effective cancer treatment”
- BU Engineering News article “Upgrading the Immune System to Fight Cancer”
5. Cho J.H., Okuma A., Al-Rubaye D., Intisar E., Junghans R.P., Wong W.W. (2018). Engineering Axl specific CAR and SynNotch receptor for cancer therapy. Scientific Reports. 8, 4–11.
6. Brenner M.J.*, Cho J.H.*, Wong N.M.L.*, Wong W.W. (2018). Synthetic Biology: Immunotherapy by Design. Annual Review of Biomedical Engineering. (*co-first author)
7. Brenner M.J.*, Cho J.H.*, Wong W.W. (2017) Synthetic biology: Sensing with modular receptors. Nature Chemical Biology, 3(2):131-132. (*co-first author)
8. Aquino P., Honda B., Jaini S., Lyubetskaya A., Hosur K., Chiu J.G., Ekladious I., Hu D., Jin L., Sayeg M.K., Stettner A.I., Wang J., Wong B.G., Wong W.S., Alexander S.L., Ba C., Bensussen S.I., Bernstein D.B., Braff D., Cha S., Cheng D.I., Cho J.H. et al., (2017). Coordinated regulation of acid resistance in Escherichia coli. BMC Systems Biology, 11(1):1.
9. Chakravarti D., Cho J.H., Weinberg B.H., Wong N.M., Wong W.W. (2016). Synthetic biology approaches in cancer immunotherapy, genetic network engineering, and genome editing. Integrative Biology, 18;8(4):504-17
10. Yu, Q., Cho, J., Shivapooja, P., López, G.P. (2013) Nanopatterned Smart Polymer Surfaces for Controlled Attachment, Killing, and Release of Bacteria., ACS Applied Materials & Interfaces, 5,19,9295-9304
Page updated
Google Sites
Report abuse