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The world’s biggest killer is ischaemic heart disease, responsible for 16% of the world’s total deaths. Since 2000, the largest increase in deaths has been for this disease, rising by more than 2 million to 8.9 million deaths in 2019. Stroke and chronic obstructive pulmonary disease are the 2nd and 3rd leading causes of death, responsible for approximately 11% and 6% of total deaths respectively.
Lower respiratory infections remained the world’s most deadly communicable disease, ranked as the 4th leading cause of death. However, the number of deaths has gone down substantially: in 2019 it claimed 2.6 million lives, 460 000 fewer than in 2000.
Neonatal conditions are ranked 5th. However, deaths from neonatal conditions are one of the categories for which the global decrease in deaths in absolute numbers over the past two decades has been the greatest: these conditions killed 2 million newborns and young children in 2019, 1.2 million fewer than in 2000.
Deaths from noncommunicable diseases are on the rise. Trachea, bronchus and lung cancers deaths have risen from 1.2 million to 1.8 million and are now ranked 6th among leading causes of death.
In 2019, Alzheimer’s disease and other forms of dementia ranked as the 7th leading cause of death. Women are disproportionately affected. Globally, 65% of deaths from Alzheimer’s and other forms of dementia are women.
One of the largest declines in the number of deaths is from diarrhoeal diseases, with global deaths falling from 2.6 million in 2000 to 1.5 million in 2019.
Diabetes has entered the top 10 causes of death, following a significant percentage increase of 70% since 2000. Diabetes is also responsible for the largest rise in male deaths among the top 10, with an 80% increase since 2000.
Other diseases which were among the top 10 causes of death in 2000 are no longer on the list. HIV is one of them. Deaths from HIV and AIDS have fallen by 51% during the last 20 years, moving from the world’s 8th leading cause of death in 2000 to the 19th in 2019.
Kidney diseases have risen from the world’s 13th leading cause of death to the 10th. Mortality has increased from 813 000 in 2000 to 1.3 million in 2019.
Nearly 1 in 3 deaths from non-melanoma skin cancer is caused by working under the sun, according to joint estimates by the World Health Organization (WHO) and the International Labour Organization (ILO) published today. The research released in Environment Internationalfinds that outdoor workers carry a large and increasing burden of non-melanoma skin cancer and calls for action to prevent this serious workplace hazard and the loss of workers’ lives it causes.
According to the joint estimates, 1.6 billion people of working age (15 years or older) were exposed to solar ultraviolet radiation while working outdoors in 2019, equivalent to 28% of all working-age people. In 2019 alone, almost 19 000 people in 183 countries died from non-melanoma skin cancer due to having worked outdoors in the sun. The majority (65%) were male.
“Unprotected exposure to solar ultraviolet radiation at work is a major cause of occupational skin cancer,” said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “But there are effective solutions to protect workers from the sun’s harmful rays, and prevent their deadly effects.”
The estimates establish occupational exposure to solar ultraviolet radiation as the work-related risk factor with the third highest attributable burden of cancer deaths globally. Between 2000 and 2019, skin cancer deaths attributable to occupational exposure to sunlight almost doubled (increasing by 88% from 10 088 deaths in 2000 to 18 960 deaths in 2019).
“A safe and healthy working environment is a fundamental right at work,” said Gilbert F. Houngbo, ILO Director-General. “Death caused by unprotected exposure to solar ultraviolet radiation while working is largely preventable through cost-effective measures. It is urgent that governments, employers and workers and their representatives work together in a framework of well-defined rights, responsibilities and duties to reduce the occupational risk of UV exposure. This can save thousands of lives every year.”
From this research, WHO calls for more action to protect workers from hazardous outdoor work in the sunlight. As skin cancer develops after years or even decades of exposure, workers must be protected from solar ultraviolet radiation at work from young working age onwards. Governments should establish, implement and enforce policies and regulations that protect outdoor workers from sun-induced skin cancer by providing shade, shifting working hours away from the solar noon, providing education and training, and equipping workers with sunscreen and personal protective clothing (such as broad-brimmed hat, long-sleeved shirts and long trousers). Protective measures should be implemented when the ultraviolet index, a scale rating the amount of skin-damaging ultraviolet radiation, is 3 or higher.
WHO, ILO, the World Meteorological Organization and the United Nations Environment Programme recently launched the SunSmart Global UV App that outdoor workers can use to estimate their exposure to solar ultraviolet radiation.
In addition, measures to reduce skin cancer risks include raising workers’ awareness of when occupational exposure to solar ultraviolet radiation occurs and that it causes skin cancer, and by providing services and programmes to detect early signs of skin cancer.
Germany deepened its longstanding engagement with WHO on Thursday with two new agreements: one to contribute a further €40 million to WHO’s work in health emergencies, and a second to host the Berlin-based WHO Hub for Pandemic and Epidemic Intelligence.
With the new contribution, Germany has provided €53.5 million so far this year to support WHO’s response to more than 50 active health emergencies.
“This is important because climate disasters, conflicts, and the ongoing pandemic demand urgent action,” said Susanne Baumann, State Secretary of the Federal Foreign Office for Germany (GFFO), whose delegation met with WHO Director-General Dr Tedros Adhanom Ghebreyesus. “Our support is flexible and vital for saving lives around the globe.”
Through the GFFO, the country provides substantial funding to humanitarian crises in Afghanistan, Libya, Ukraine, Yemen, and to Ebola responses in Africa.
Germany is an all-time top donor to WHO’s Contingency Fund for Emergencies (CFE), having contributed €115 million since the CFE’s inception in 2015. The contributions have made a significant impact on the health of people caught up in humanitarian crises; this year alone, CFE funding allowed WHO to bring immediate, lifesaving support to victims of floods in Libya, conflict in Sudan, cholera and diphtheria outbreaks, and earthquakes in Türkiye and Syria.
Of the new €40 million contribution, €20 million goes to the WHO Health Emergencies Appeal 2023, €10 million to the Ukraine emergency, €10 million for emergencies in Africa.
New analysis confirms world seeing an upsurge of cholera
Current data for 2023 suggest that this global upsurge is continuing. Twenty-four countries are currently reporting active outbreaks, with some countries in the midst of acute crises.
The increased demand for cholera materials has been a challenge for disease control efforts globally. Since October 2022, the International Coordinating Group (ICG)—the body which manages emergency supplies of vaccines—has suspended the standard two-dose vaccination regimen in cholera outbreak response campaigns, using instead a single-dose approach.
WHO is supporting countries to respond to cholera outbreaks on an emergency footing through the strengthening of public health surveillance, case management, and prevention measures; providing essential medical supplies; coordinating field deployments with partners; and supporting risk communication and community engagement.