2023
Cho J, Min HY, Lee HY. Isolation of slow-cycling cancer cells from lung patient-derived xenograft using carboxyfluorescein-succinimidyl ester retention-mediated cell sorting. STAR Protoc. (2023) 15;4(2):102167
2022
Min HY*, Cho J*, Sim JY*, Boo HJ*, Lee JS, Lee SB, Lee YJ, Kim SJ, Kim KP, Park IJ, Hong SM, Zhang XL, Zhang ZG, Park RW, Lee HY. S100A14: A novel negative regulator of cancer stemness and immune evasion by inhibiting STAT3-mediated programmed death-ligand 1 expression in colorectal cancer. Clin. Transl. Med. (2022) 12(7):e986. *co-first authors
Hyun SY, Min HY, Lee HJ, Cho J, Boo HJ, Noh M, Jang HJ, Lee HJ, Park CS, Park JS, Shin YK, Lee HY. Ninjurin1 drives lung tumor formation and progression by potentiating Wnt/β-Catenin signaling through Frizzled2-LRP6 assembly. J Exp Clin Cancer Res. (2022) 41(1):133.
2021
Le HT, Lee HJ, Cho J, Min HY, Lee JS, Lee SJ, Lee HY. Insulin-Like Growth Factor Binding Protein-3 Exerts Its Anti-Metastatic Effect in Aerodigestive Tract Cancers by Disrupting the Protein Stability of Vimentin. Cancers. (2021) 13(5):1041.
Cho J, Min HY, Lee HJ, Hyun SY, Sim JY, Noh M, Hwang SJ, Park SH, Boo HJ, Lee HJ, Hong S, Park RW, Shin YK, Hung MC, Lee HY. RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse. J Clin Invest. (2021) 131(1):e136779.
2020
Cho J*, Min HY*, Pei H, Wei X, Sim JY, Park SH, Hwang SJ, Lee HJ, Hong S, Shin YK, Lee HY. The ATF6-EGF pathway mediates the awakening of slow-cycling chemoresistant cells and tumor recurrence by stimulating tumor angiogenesis. Cancers. (2020) 12(7):1772. *co-first authors
Cho YH, Ro EJ, Yoon JS, Kwak DK, Cho J, Kang DW, Lee HY, Choi KY. Small molecule-induced simultaneous destabilization of β-catenin and RAS is an effective molecular strategy to suppress stemness of colorectal cancer cells. Cell Commun Signal. (2020) 18(1):38.
Cho J*, Lee HJ*, Hwang SJ, Min HY, Kang HN, Hyun SY, Sim JY, Lee HJ, Jang HJ, Suh YA, Hong S, Shin YK, Kim HR, Lee HY. The interplay between slow-cycling, chemoresistant cancer cells and fibroblasts creates a proinflammatory niche for tumor progression. Cancer Res. (2020) 80:2257–72. *co-first authors
Min HY, Pei H, Hyun SY, Boo HJ, Jang HJ, Cho J, Kim JH, Son J, Lee HY. Potent anticancer effect of the natural steroidal saponin Gracillin is produced by inhibiting glycolysis and oxidative phosphorylation-mediated bioenergetics. Cancers. (2020) 12(4):913.
2019
Park J, Cho YH, Shin WJ, Lee SK, Lee J, Kim T, Cha PH, Yang JS, Cho J, Min DS, Han G, Lee HY, Choi KY. A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer. Sci Rep. (2019) 9:648.
2015-2017
Min HY, Lee SC, Woo JK, Jung HJ, Park KH, Jeong HM, Hyun SY, Cho J, Lee W, Park JE, Kwon SJ, Lee HJ, Ni X, Shin YK, Johnson FM, Duvic M, Lee HY. Essential role of DNA methyltransferase 1-mediated transcription of insulin-like growth factor 2 in resistance to histone deacetylase inhibitors. Clin Cancer Res. (2017) 23(5):1299-1311.
Lee SC, Min HY, Jung HJ, Park KH, Hyun SY, Cho J, Woo JK, Kwon SJ, Lee HJ, Johnson FM, Lee HY. Essential role of insulin-like growth factor 2 in resistance to histone deacetylase inhibitors. Oncogene. (2016) 35(42):5515-26
Kim IK, Kim BS, Koh CH, Seok JW, Park JS, Shin KS, Bae EA, Lee GE, Jeon H, Cho J, Jung Y, Han D, Kwon BS, Lee HY, Chung Y, Kang CY. Glucocorticoid-induced tumor necrosis factor receptor-related protein co-stimulation facilitates tumor regression by inducing IL-9-producing helper T cells. Nat Med. (2015) 21(9):1010-7.
Min HY, Yun HJ, Lee JS, Lee HJ, Cho J, Jang HJ, Park SH, Liu D, Oh SH, Lee JJ, Wistuba II, Lee HY. Targeting the insulin-like growth factor receptor and Src signaling network for the treatment of non-small cell lung cancer. Mol Cancer. (2015) 14:113