Expanding from a local brand into an international e-commerce player is a bold move — and entering the United States market is often the ultimate goal. The US offers a vast customer base, high digital adoption, and a mature infrastructure for online commerce. But for businesses looking to go global, the key challenge is knowing where and how to launch successfully.
Whether you’re a local seller from Southeast Asia, a European startup, or a Middle Eastern brand with a loyal regional following, launching your online store in the United States requires careful platform selection. In 2025, the competition is fierce, but the opportunity is immense — and the tools are more powerful than ever.
Here are the top e-commerce platforms that help local businesses scale globally and build a thriving presence in the US.
Before choosing a platform, it’s important to understand why so many sellers worldwide set their sights on the US.
Massive Online Consumer Base: Over 270 million Americans are active online shoppers.
High Average Order Values: US customers tend to spend more per transaction.
Familiarity with Cross-Border Shopping: American consumers are increasingly comfortable buying from international brands.
Robust Infrastructure: Warehousing, payment systems, and customer service platforms are readily available.
Scalability: A foothold in the US can unlock long-term growth and brand credibility.
The transition from local to global is a strategic shift. And with the right e-commerce platform, it’s more achievable than ever.
Shopify is one of the best tools for local sellers who want to scale globally on their terms. It allows you to create a branded online store tailored for the US market, manage orders, accept payments in USD, and integrate with US-based logistics providers.
Shopify Highlights for Global Sellers:
Customizable storefront with .com domain targeting US shoppers
Localized checkout with tax and shipping calculators
Seamless integration with fulfillment centers and USPS, FedEx, or UPS
Supports major global payment gateways like Stripe, PayPal, and Wise
Connects to US social media and marketplace channels
Shopify is ideal for businesses that want to retain full ownership of their brand, data, and customer experience while selling internationally.
For immediate visibility and access to millions of US shoppers, Amazon is unmatched. Through Amazon Global Selling and Fulfillment by Amazon (FBA), local businesses can scale their operations in the US with speed and efficiency.
Why Amazon Works for Global Expansion:
Built-in trust and Prime delivery make conversions easier
FBA handles US warehousing, delivery, and returns
Access to advanced analytics and product promotion tools
Sell in high-traffic categories like electronics, home, and beauty
Eligible for Amazon Brand Registry to protect your IP
If your business already has a winning product in your home market, Amazon can help validate and scale it in the US rapidly.
Walmart has opened its online marketplace to select global sellers and offers strong support for those ready to meet its high standards. If accepted, sellers benefit from Walmart’s reputation, logistics power, and massive reach across the US.
Walmart Marketplace Features:
Access to 120M+ unique US visitors monthly
Fast, affordable shipping via Walmart Fulfillment Services (WFS)
Strong categories: home goods, groceries, electronics, personal care
Enhanced brand credibility among US shoppers
Detailed sales dashboards and advertising options
Walmart is ideal for established local brands looking to enter the US retail ecosystem in a reputable and scalable way.
Etsy is the go-to platform for handmade, artistic, vintage, or personalized items — and it’s especially popular with American buyers who value craftsmanship and authenticity. For local artisans and niche sellers, Etsy offers an organic path to global visibility.
Why Etsy Is Perfect for Going Global:
Low barrier to entry, no large inventory required
International seller support with tax and shipping tools
Integrated payments and US dollar conversion
High customer trust in seller-made goods
Categories include jewelry, stationery, clothing, home décor
If your local products carry a story or craft value, Etsy can connect you directly to passionate US buyers who value those qualities.
BigCommerce is a powerful SaaS platform designed for scaling businesses. It provides all the backend tools necessary to support US operations, from tax compliance and payments to integrations with US warehousing.
Key BigCommerce Benefits:
Multi-storefront capability to serve US and global markets
Fast, mobile-optimized storefronts
Native integrations with Amazon, eBay, Google Shopping, and Meta
Supports US shipping, tax, and B2B invoicing
Scalable for medium to large enterprises
BigCommerce suits sellers who already have traction locally and want to level up with a unified platform for managing US and global operations.
eBay remains a reliable platform for global sellers, particularly those dealing in refurbished, used, or rare items. It’s also a useful channel for new or branded goods in specialized categories.
eBay Strengths for International Launches:
Low entry cost with wide exposure
Built-in buyer protections and shipping solutions
Trusted by millions of US consumers across generations
Strong categories: electronics, collectibles, auto parts, fashion
Easy to test different markets without building a site
Sellers from all over the world — from tech refurbishers in China to vintage boutiques in Italy — have used eBay as a springboard into the US market.
Facebook and Instagram Shops let you sell directly on social platforms. US shoppers, particularly millennials and Gen Z, are increasingly buying via Instagram and Facebook ads — making Meta a key tool for launching online in America.
Social Commerce Advantages:
Highly targeted ad campaigns based on US interests and behavior
In-app shopping experience linked to your Shopify or website
Tools for influencer marketing and user-generated content
Direct messaging for customer engagement and support
Strong visual formats for fashion, beauty, and home goods
Meta Shops are particularly valuable for local DTC brands looking to create a buzz and build a loyal US audience from day one.
Localize Your Store: Use American English, US dollars, and region-specific sizing or standards.
Invest in Logistics: Choose fulfillment partners with US warehouses to ensure fast delivery.
Understand Tax Rules: Use automated tools to handle sales tax compliance across US states.
Build Customer Support: Offer support in US time zones and be responsive via email or chat.
Run US-Focused Marketing: Use paid ads and influencer collaborations targeting US audiences.
Launching in the US isn’t just about translating your store; it’s about transforming your business model for a new, fast-paced, and consumer-savvy market.
Q: Can a small business from outside the US sell online in America?
A: Absolutely. Platforms like Etsy, Shopify, Amazon, and eBay make it easier than ever for small businesses to sell in the US.
Q: What’s the best platform to start with if I have no US entity?
A: Shopify and Etsy are ideal starting points. Amazon also supports global sellers with the right documentation.
Q: Do I need to use a US fulfillment center?
A: It’s highly recommended for fast shipping and better customer experience, especially on Amazon and Walmart.
Q: How do I collect payments from US buyers?
A: Most platforms support Payoneer, Stripe, PayPal, and Wise, allowing seamless payments in USD.
Q: Is branding important for US buyers?
A: Very. US consumers trust brands with professional stores, clear policies, and consistent messaging.
Going from a local brand to a global seller takes vision, strategy, and the right tools. The US market is rich with opportunity — and today’s e-commerce platforms are built to help you launch confidently and compete globally.
Whether you're a solo artisan or an ambitious tech brand, choosing the right platform is your first step toward global success. With localized content, smart logistics, and great customer service, your local brand can become a global success story — starting with the United States.